IDO
La indoleamina 2,3-dioxigenasa (IDO) es una enzima involucrada en el catabolismo del triptófano, que lleva a la producción de quinurenina y otros metabolitos. La IDO juega un papel en la tolerancia inmune y a menudo está sobreexpresada en el cáncer y en condiciones inflamatorias crónicas. Los inhibidores de IDO se están explorando como posibles agentes inmunoterapéuticos en el cáncer y en enfermedades autoinmunes. En CymitQuimica, ofrecemos inhibidores de IDO para apoyar su investigación en inmunología, oncología y regulación metabólica.
Se han encontrado 84 productos de "IDO"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
PCC0208009
CAS:PCC0208009 (IDO-IN-2) is an IDO inhibitor.Fórmula:C29H35N7OPureza:99.89%Forma y color:SolidPeso molecular:497.63IDO5L
CAS:IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM).Fórmula:C9H7ClFN5O2Pureza:99.49% - 99.75%Forma y color:SolidPeso molecular:271.64PF-06840003
CAS:PF-06840003 (EOS200271) is a specific and oral active IDO-1 inhibitor.Fórmula:C12H9FN2O2Pureza:99.10%Forma y color:SolidPeso molecular:232.21Necrostatin 2 racemate
CAS:<p>Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.</p>Fórmula:C13H12ClN3O2Pureza:98% - 99.5%Forma y color:SolidPeso molecular:277.71DP00477
CAS:DP00477, a potent inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), exhibits an inhibitory concentration (IC50) of 7.0 µM.Fórmula:C17H11ClF3N3OSForma y color:SolidPeso molecular:397.8IDO-IN-12
CAS:IDO-IN-12 is an inhibitor of indoleamine 2,3-dioxygenase (IDO).Fórmula:C13H11BrFN5O3SPureza:99.727%Forma y color:SolidPeso molecular:416.23IACS-8968 S-enantiomer
CAS:IACS-8968 S-enantiomer is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).Fórmula:C17H18F3N5O2Pureza:98%Forma y color:SolidPeso molecular:381.35IACS-8968
CAS:IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).Fórmula:C17H18F3N5O2Pureza:98%Forma y color:SolidPeso molecular:381.35IDO1-IN-18
CAS:IDO1-IN-18 (Compound 14) is a potent inhibitor of IDO1. IDO1-IN-18 has potential for cancer disease research.Fórmula:C23H18F4N2O3Forma y color:SolidPeso molecular:446.39IDO-IN-8
CAS:IDO-IN-8 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM).Fórmula:C18H21FN2O2Pureza:98%Forma y color:SolidPeso molecular:316.37IDO-IN-6
CAS:IDO-IN-6 is an indoleamine 2,3-dioxygenase (IDO) inhibitor.Fórmula:C18H21FN2O2Pureza:98%Forma y color:SolidPeso molecular:316.37IDO1-IN-2
CAS:IDO1-IN-2 is a potent and selective IDO1 inhibitor with IC50s of 81 nM, 59 nM (mouse), and 28 nM (rat), respectively. It has anti-cancer activity.Fórmula:C15H17FN6O4Pureza:98%Forma y color:SolidPeso molecular:364.33IDO-IN-3
CAS:IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 290 nM).Fórmula:C11H12BrFN6O2Forma y color:SolidPeso molecular:359.15IDO-IN-11
CAS:IDO-IN-11 is an indoleamine-2,3-dioxygenase (IDO) inhibitor with IC50s of 0.18 μM (Kinase) and 0.014 μM (Hela Cell).Fórmula:C19H23BrFN7O4SPureza:98%Forma y color:SolidPeso molecular:544.4IDO1/TDO-IN-3
CAS:IDO1/TDO-IN-3 inhibits IDO1 (IC50: 0.005 μM) and TDO (IC50: 0.004 μM) with strong anti-tumor activity and low toxicity.Fórmula:C16H6ClF2N3O2Forma y color:SolidPeso molecular:345.69IDO-IN-4
CAS:IDO-IN-4 is an indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor.Fórmula:C26H35N3O3Forma y color:SolidPeso molecular:437.57IDO1-IN-16
CAS:IDO1-IN-16 (I-1) is an IDO1 inhibitor that targets holo-IDO1 (IC50: 127 nM).Fórmula:C25H35BrFN5O2Forma y color:SolidPeso molecular:536.48IACS-8968 R-enantiomer
CAS:IACS-8968 R-enantiomer is the R-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor (pIC50s: 6.43 for IDO and <5 for TDO).Fórmula:C17H18F3N5O2Pureza:98%Forma y color:SolidPeso molecular:381.35IDO1/TDO-IN-2
CAS:IDO1/TDO-IN-2: IDO1/TDO inhibitor; IC50s: IDO1, 0.1μM; TDO, 0.07μM; potential for cancer research.Fórmula:C16H9N3O2Forma y color:SolidPeso molecular:275.26IDO/TDO-IN-1
CAS:IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM).Fórmula:C25H24FN5Pureza:98%Forma y color:SolidPeso molecular:413.49
