PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Se han encontrado 164 productos de "PPAR"
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GED-0507-34 Levo
CAS:<p>GED-0507-34 Levo,(S)-3-(4-Aminophenyl)-2-methoxypropanoic acid,an orally available PPARγ modulator for amelioration of inflammation-driven intestinal fibrosis.</p>Fórmula:C10H13NO3Pureza:98.19%Forma y color:SolidPeso molecular:195.22Fenofibric acid
CAS:<p>Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.</p>Fórmula:C17H15ClO4Pureza:99.36%Forma y color:White Or Almost White Crystalline PowderPeso molecular:318.75Magnolol
CAS:<p>Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.</p>Fórmula:C18H18O2Pureza:99.49%Forma y color:A Bioactive Compound Found In The Bark Of The Houpu MagnoliaPeso molecular:266.33Clofibric acid
CAS:<p>Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.</p>Fórmula:C10H11ClO3Pureza:99.47% - 99.8%Forma y color:Pale Yellow SolidPeso molecular:214.65NTP42
CAS:<p>NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)</p>Fórmula:C25H23F2N3O5SPureza:97.55%Forma y color:SolidPeso molecular:515.53LY518674
CAS:<p>LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis.</p>Fórmula:C23H27N3O4Pureza:98.87%Forma y color:SolidPeso molecular:409.48Daidzein
CAS:<p>Daidzein (Isoflavone) is an isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein.</p>Fórmula:C15H10O4Pureza:98.08%Forma y color:SolidPeso molecular:254.24EHP-101
CAS:<p>EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.</p>Fórmula:C28H35NO3Pureza:98.36%Forma y color:SolidPeso molecular:433.58Retinoic acid
CAS:<p>Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.</p>Fórmula:C20H28O2Pureza:97.21% - 99.6%Forma y color:Yellow-Orange PowderPeso molecular:300.44MK-0533
CAS:<p>MK-0533 is a novel PPARγ partial agonist for the prevention of vascular endothelial dysfunction (VED) and VED-related cardiovascular disease.</p>Fórmula:C28H24F3NO6Pureza:99.03%Forma y color:SoildPeso molecular:527.49MA-0204
CAS:<p>MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human,</p>Fórmula:C25H27F3N2O4Pureza:97.8%Forma y color:SolidPeso molecular:476.49NSC-87877
CAS:<p>NSC-87877 inhibits Shp2 (IC50=0.318μM), Shp1 (IC50=0.355μM), and DUSP26 phosphatases.</p>Fórmula:C19H13N3O7S2Pureza:97.35%Forma y color:SolidPeso molecular:459.45Arhalofenate
CAS:<p>Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.</p>Fórmula:C19H17ClF3NO4Pureza:98.97%Forma y color:SolidPeso molecular:415.79Candesartan
CAS:<p>Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.</p>Fórmula:C24H20N6O3Pureza:98.3% - 99.55%Forma y color:Colorless Solid CrystallinePeso molecular:440.47Pioglitazone hydrochloride
CAS:<p>Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic</p>Fórmula:C19H20N2O3S·HClPureza:99.64% - >99.99%Forma y color:White Crystals Or Crystalline PowderPeso molecular:392.90Anandamide
CAS:<p>Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also</p>Fórmula:C22H37NO2Pureza:95.037% - 99.22%Forma y color:Light Yellow OilPeso molecular:347.53Muraglitazar
CAS:<p>Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia.</p>Fórmula:C29H28N2O7Pureza:99.17%Forma y color:SolidPeso molecular:516.54Oleoylethanolamide
CAS:<p>Oleoylethanolamide (N-Oleoylethanolamide) is a high affinity endogenous agonist of PPAR-α.</p>Fórmula:C20H39NO2Pureza:99.98%Forma y color:SolidPeso molecular:325.53Mifobate
CAS:<p>Mifobate (SR-202) 是一种有效且特异性的 PPARγ拮抗剂，可选择性抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性，IC50为140 μM，具有抗肥胖和抗糖尿病作用。</p>Fórmula:C11H17ClO7P2Pureza:99.12%Forma y color:SolidPeso molecular:358.65Pioglitazone
CAS:<p>Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!</p>Fórmula:C19H20N2O3SPureza:95% - 99.57%Forma y color:White PowderPeso molecular:356.44
