PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Se han encontrado 179 productos para "PPAR".
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PPAR agonist 4
PPAR agonist4 (Compound 12) is an orally active PPAR agonist that activates PPARα, PPARδ, and PPARγ with EC50 values of 0.7 μM, 0.7 μM, and 1.8 μM, respectively. It also exhibits anti-hepatic fibrosis activity.Fórmula:C23H28F3N3O3Peso molecular:451.20828Anti-osteoporosis agent-10
Anti-osteoporosis agent-10 is an inhibitor of osteoporosis that suppresses the formation of osteoclasts with an IC50 of 0.042 μM. It also exhibits antagonistic activity towards PPARγ, with an EC50 value of 0.75 μM.Forma y color:Odour SolidPPAR agonist 6
PPAR agonist6 (compound 5a) acts as an agonist for PPAR, exhibiting EC50 values of 3.6 μM and 2.6 μM for PPARα and PPARβ/δ respectively. Additionally, PPAR agonist6 inhibits the transactivation of a TNFα-dependent NF-κB-driven reporter gene in L929 cells [1].Forma y color:Odour SolidLipid Metabolism Compound Library
A unique collection of xnum compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).Forma y color:Odour SolidRef: TM-L2510
1mgA consultar10μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultarSulotroban potassium
Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.Fórmula:C16H16KNO5SPureza:98.02%Forma y color:SoildPeso molecular:373.46MCC-555
CAS:MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects.Fórmula:C21H16FNO3SPureza:99.07% - 99.82%Forma y color:SolidPeso molecular:381.42Sulotroban
CAS:sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.Fórmula:C16H17NO5SPureza:98.86% - 99.98%Forma y color:SolidPeso molecular:335.37Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-
CAS:Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM.Fórmula:C24H23NO5SPureza:99.59%Forma y color:SolidPeso molecular:437.51WAY-620472
CAS:WAY-620472 is a PPAR regulator that can be used to alter the lifespan of eukaryotes.Fórmula:C23H21N5OSPureza:98.99%Forma y color:SolidPeso molecular:415.51CUDA
CAS:CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.Fórmula:C19H36N2O3Pureza:97.58%Forma y color:SolidPeso molecular:340.5Nuclear Receptor Compound Library
A unique collection of xnum nuclear receptor signaling targeted compounds for high throughput and high content screening;Forma y color:Odour SolidRef: TM-L1510
1mgA consultar10μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultarCC618
CAS:CC618 is a selective PPARβ/δ antagonist with an IC50 of 10.0 μM.Fórmula:C20H15F6N3O3S2Pureza:99.94%Forma y color:SolidPeso molecular:523.47Ref: TM-T9767
1mg102,00€5mg235,00€1mL*10mM (DMSO)268,00€10mg349,00€25mg532,00€50mg745,00€100mg999,00€AZD-9574
CAS:AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs.Fórmula:C21H22F2N6O2Pureza:98.46% - 99.39%Forma y color:SolidPeso molecular:428.44Hydrangeic acid
CAS:Hydrangeic acid is an orally effective stilbene-type glycolipid metabolism regulator that lowers blood glucose and lipids. This compound can be isolated from processed leaves of Hydrangea macrophylla var. thunbergii. It is linked to glucose-lipid metabolism and insulin sensitivity regulation. Hydrangeic acid does not directly activate PPARγ or PPARα; instead, it enhances the mRNA expression of adiponectin, PPARγ2, GLUT4, and fatty acid-binding protein aP2 while reducing TNF-α mRNA levels, thereby promoting adipogenesis, glucose uptake, and GLUT4 translocation in 3T3-L1 cells. Additionally, it suppresses the production of NO induced by inflammatory factors, improving insulin resistance. Hydrangeic acid is useful for research related to type 2 diabetes and does not cause liver weight gain.Fórmula:C15H12O4Peso molecular:256.26PPAR α/PPARA Protein, Human, Recombinant (His)
PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:31.36 kDa (predicted)CP-868388 free base
CAS:CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.Fórmula:C26H33NO5Pureza:99.84%Forma y color:White SolidPeso molecular:439.54Balaglitazone
CAS:Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.Fórmula:C20H17N3O4SPureza:99.74%Forma y color:SolidPeso molecular:395.43PPAR α/PPARA Protein, Mouse, Recombinant (His)
PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E.Forma y color:White Lyophilized PowderPeso molecular:31.49 kDa (predicted)Ref: TM-TMPY-06837
5µg101,00€10µg166,00€20µg266,00€50µg540,00€100µg954,00€200µg1.665,00€500µg4.078,00€Candesartan-D4
CAS:Candesartan-d4 is the deuterated Candesartan; AT1 receptor blocker and PPAR-γ agonist; antihypertensive; internal standard for PK analysis.Fórmula:C24H20N6O3Pureza:98%Forma y color:White SolidPeso molecular:444.479Cinnamyl Alcohol (Standard)
CAS:Cinnamyl Alcohol (Standard) is the standard substance of Cinnamyl Alcohol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.Fórmula:C9H10OPeso molecular:134.1751
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