
Ácido graso sintasa
La sintasa de ácidos grasos (FAS) es un complejo multi-enzimático responsable de la síntesis de ácidos grasos de cadena larga. La sobreexpresión de FAS está asociada con varios trastornos metabólicos, incluyendo la obesidad, la diabetes y el cáncer. Inhibir FAS puede reducir la biosíntesis de lípidos e inducir apoptosis en células cancerosas, lo que la convierte en un objetivo prometedor para la terapia contra el cáncer y la investigación de enfermedades metabólicas. En CymitQuimica, ofrecemos una variedad de inhibidores de FAS para apoyar su investigación en oncología, metabolismo y desarrollo terapéutico.
Se han encontrado 37 productos de "Ácido graso sintasa"
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Denifanstat
CAS:Denifanstat (FASN-IN-2) is a FASN inhibitor with selective and oral activity. Denifanstat has been used in studies of steatohepatitis. Cost effective and quality assured.Fórmula:C27H29N5OPureza:98.33% - 99.35%Forma y color:SolidPeso molecular:439.55PF429242 dihydrochloride
CAS:<p>PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).</p>Fórmula:C25H37Cl2N3O2Pureza:99.68%Forma y color:SolidPeso molecular:482.49trans-C75
CAS:trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).Fórmula:C14H22O4Pureza:98.88% - 99.57%Forma y color:White To Off-White SolidPeso molecular:254.32FASN-IN-3
CAS:FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).Fórmula:C24H24N4OPureza:97.41%Forma y color:SolidPeso molecular:384.47CTL-12
CTL-12, a fatty acid synthase (FASN) inhibitor (IC50: 2.5 μM), induces apoptosis and disrupts the cell cycle at the Sub-G1/S phase.Fórmula:C22H21ClN4O4Forma y color:SolidPeso molecular:440.88Fasnall HCl
Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites.Fórmula:C19H23ClN4SPureza:99.97%Forma y color:SoildPeso molecular:374.93IPI-9119
CAS:IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).Fórmula:C24H19F2N5O5Pureza:99.81%Forma y color:SolidPeso molecular:495.43FASN-IN-4 tosylate
CAS:FASN-IN-4 tosylate: Fatty acid synthase inhibitor, IC50 10 nM; blocks SARS-CoV-2, EC50 18.6 nM.Fórmula:C33H35N3O7S2Forma y color:SolidPeso molecular:649.78Betulin ditosylate
CAS:<p>Betulinditosylate is a derivative of Betulin, which functions as an SREBP inhibitor.</p>Fórmula:C44H62O6S2Forma y color:SolidPeso molecular:751.09FASN/SCD-IN-1
FASN/SCD-IN-1 is a Silybin derivative and an orally active inhibitor of fatty acid synthase (FASN) and stearoyl-CoA desaturase (SCD). In vitro, FASN/SCD-IN-1 demonstrates the ability to inhibit lipid deposition, reduce the transcription levels of FASN and SCD, and exhibits antioxidant, anti-inflammatory, and antifibrotic activities. It shows significant hepatoprotective effects in rat models of acute liver injury and improves pathological features such as steatosis, inflammation, and fibrosis in a mouse model of myeloproliferative-associated steatohepatitis (MASH). FASN/SCD-IN-1 can be used for MASH research.Forma y color:Odour SolidCTL-06
CTL-06, a Fatty Acid Synthase (FASN) inhibitor with an IC50 of 3 μM, induces apoptosis, while CTL-12 impedes cell cycle progression in the Sub-G1/S phase andFórmula:C21H21ClN4O4Forma y color:SolidPeso molecular:428.87ACSS2-IN-2
CAS:MTB-9655 inhibits ACSS2 with 3.8 nM IC50, useful in research of viral, metabolic, neuropsychiatric diseases, inflammation, and cancer.Fórmula:C21H19F2N3O4Pureza:99.5%Forma y color:SoildPeso molecular:415.39Lipid Metabolism Compound Library
<p>A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).</p>Forma y color:Odour SolidFASN Protein, Human, Recombinant (His)
FASN Protein, Human, Recombinant (His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:35.26 kDa (predicted)Anti-FASN Antibody (6U56)
Anti-FASN Antibody (6U56) is an antibody targeting FASN. Anti-FASN Antibody (6U56) can be used in ELISA, IF, FCM.Forma y color:Odour LiquidGSK2194069
CAS:GSK2194069: Fatty acid synthase inhibitor, β-keto reductase-specific, IC50 7.7 nM, hampers cancer cell proliferation.Fórmula:C25H24N4O3Pureza:98.759% - 99.84%Forma y color:SolidPeso molecular:428.48BI 99179
CAS:<p>BI 99179 is a selective and potent inhibitor of type I fatty acid synthase (FAS), a tool compound for targeting FAS for cancer research.</p>Fórmula:C23H25N3O3Pureza:98.73%Forma y color:SolidPeso molecular:391.46FASN Protein, Mouse, Recombinant (His)
FASN Protein, Mouse, Recombinant (His) is expressed in E.Pureza:≥ 95 % as determined by SDS-PAGE. - ≥ 95 % as determined by SDS-PAGE.Forma y color:Lyophilized PowderPeso molecular:34.23 kDa (predicted)FT113
CAS:FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activityFórmula:C22H20FN3O4Pureza:97.05%Forma y color:SolidPeso molecular:409.41Fas C-Terminal Tripeptide Acetate
Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.Fórmula:C18H33N3O8Pureza:99.12%Forma y color:SolidPeso molecular:419.47

