Deshidrogenasa
Las deshidrogenasas son enzimas involucradas en las reacciones de oxidación-reducción de las vías metabólicas, desempeñando un papel central en la producción de energía y la respiración celular. Estas enzimas son cruciales para procesos como el ciclo del ácido cítrico, la glucólisis y la oxidación de ácidos grasos. Los inhibidores de deshidrogenasas son herramientas importantes en el estudio de enfermedades metabólicas, cáncer y estrés oxidativo. En CymitQuimica, ofrecemos una selección completa de inhibidores de deshidrogenasas para apoyar su investigación en metabolismo, biología del cáncer y bioquímica.
Se han encontrado 319 productos para "Deshidrogenasa".
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IGUANA-1
CAS:IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.Fórmula:C27H26ClN3O4Pureza:99.08%Forma y color:SolidPeso molecular:491.97Ref: TM-T73377
1mg49,00€5mg105,00€1mL*10mM (DMSO)111,00€10mg166,00€25mg301,00€50mg452,00€100mg658,00€LDH-IN-3
LDH-IN-3 (compound E38) is an inhibitor of lactate dehydrogenase (LDH) and a potential protective agent against ischemic neuronal damage in the eyes and brain. It functions through the HO-1/SIRT1 pathway.Fórmula:C32H27NO5Forma y color:SolidPeso molecular:505.56Succinate dehydrogenase-IN-4
Succinate dehydrogenase-IN-4 (Compound 4b) is an inhibitor of succinate dehydrogenase with an IC50 value of 3.38 μM. It exhibits antifungal activity against Physalospora piricola and Colletotrichum orbiculare, with EC50 values of 16.33 μM and 18.06 μM, respectively.Fórmula:C20H21N3O2S2Forma y color:SolidPeso molecular:399.53LDHA-IN-5
CAS:LDHA-IN-5 is a novel and potent inhibitor targeting both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), designed for the treatment of primaryFórmula:C27H22FN7O6S3Forma y color:SolidPeso molecular:655.7MTHFD2-IN-4 sodium
MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].Fórmula:C26H21F6N2NaO5Forma y color:SolidPeso molecular:578.44LDHA-IN-8
CAS:LDHA-IN-8, an inhibitor, inhibits the proliferation of pancreatic and lung cancer cells, decreasing the intracellular lactate content and increasing ROS levels.Fórmula:C15H14N4O2Pureza:99.73%Forma y color:Yellow SolidPeso molecular:282.3DSM705
CAS:DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.Fórmula:C19H19F3N6OForma y color:SolidPeso molecular:404.397SCD1 inhibitor-3
CAS:SCD1 inhibitor-3 (ML-270) is a highly effective and orally available compound that inhibits SCD1 with remarkable safety.Fórmula:C19H16FN7O2Pureza:99.5%Forma y color:SolidPeso molecular:393.37Ref: TM-T38683
1mg87,00€5mg177,00€1mL*10mM (DMSO)195,00€10mg281,00€25mg480,00€50mg692,00€100mg973,00€hDHODH-IN-13
CAS:hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications inForma y color:Solid(Rac)-BMS-816336
(Rac)-BMS-816336 is a racemic 11β-HSD1 inhibitor; IC50: 10 nM (human), 68 nM (mouse), metabolically stable.Fórmula:C21H27NO3Pureza:98%Forma y color:SolidPeso molecular:341.44DSM1465
DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.Fórmula:C17H12ClF6N5O2Forma y color:SolidPeso molecular:467.753PDK-IN-1
CAS:PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.Fórmula:C20H16BrN7OForma y color:SolidPeso molecular:450.29LDHA-IN-3
CAS:LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.Fórmula:C13H9F3SePureza:99.71%Forma y color:SolidPeso molecular:301.17Ref: TM-T39805
1mg52,00€5mg113,00€1mL*10mM (DMSO)124,00€10mg177,00€25mg371,00€50mg517,00€100mg707,00€200mg973,00€MTHFD2-IN-3
MTHFD2-IN-3 (compound 10), a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2), demonstrates significant efficacy in obstructing the activityFórmula:C22H19NO7SForma y color:SolidPeso molecular:441.45D-Lactate dehydrogenase
CAS:D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.Forma y color:SolidBMS-770767
CAS:BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.Fórmula:C19H18ClN3O2Forma y color:SolidPeso molecular:355.82MTHFD2-IN-1
MTHFD2-IN-1 (compound 12) is a potent inhibitor of methylenetetrahydrofolate dehydrogenase (MTHFD2) [1].Fórmula:C24H21NO6Forma y color:SolidPeso molecular:419.43IGUANA-1 free base
CAS:IGUANA-1: selective ALDH1 B1 inhibitor, IC50=30 nM, hinders SW480 cell growth with IC50=2.46/0.39 μM in adherent/spheroid forms, for cancer research.Fórmula:C26H24ClN3O2Forma y color:SolidPeso molecular:445.9411β-HSD1-IN-11
CAS:11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13Fórmula:C15H11F3O3SPureza:99.61%Forma y color:SolidPeso molecular:328.31Ref: TM-T60149
1mg109,00€1mL*10mM (DMSO)239,00€5mg241,00€10mg355,00€25mg532,00€50mg745,00€100mg1.018,00€500mg2.043,00€DHODH-IN-18
CAS:DHODH-IN-18 is a human DHODH inhibitor ( IC 50 = 0.2 nM).Fórmula:C21H16ClF5N6O4Forma y color:SolidPeso molecular:546.84
