AhR

Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells.

BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from …

Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis.

Diosmin is a bioflavonoid that strengthens vascular walls.

Mexiletine Hydrochloride is the hydrochloride salt form of mexiletine, a local anesthetic and antiarrhythmic (Class …

GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit …

WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.

3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.

MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM …

Phortress is a high affinity AhR ligand that elicits antitumor activity by inducing transcription of …

D-Kynurenine is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and …

PDM 2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist.

Butyl benzyl phthalate is used as a plasticizer for PVC.

CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, …

YL-109, a novel anticancer agent, can inhibit breast Y cell growth and invasiveness in vitro …

Skatole is produced by intestinal bacteria. Skatole regulates intestinal epithelial cellular functions through activating aryl …

PD98059 is a non-ATP competitive MEK inhibitor (IC50: 2/50 μM for MEK1/MEK2).

Indole-3-pyruvic Acid is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone …

Indole-3-carbinol, a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and …

Prochloraz is a broad-spectrum contact imidazole fungicide. Prochloraz inhibits human placental microsomal aromatase in vitro …

Pifithrin-α is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.

VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with …

5-fluoro 203 is a cytotoxic molecule leading to cell death by forming DNA adducts. 5-fluoro …

Indoxyl sulfate (potassium salt) is an agonist for the human aryl hydrocarbon receptor (AHR). The …

StemRegenin 1 is an aryl hydrocarbon receptor (AhR) inhibitor.

Brevifolincarboxylic acid is a natural product isolated from Polygonum capitatum, it has inhibitory effect on …

Carbidopa Hydrate is an inhibitor of DOPA decarboxylase, preventing the conversion of levodopa to dopamine.

CH-223191 is a potent and specific antagonist for aryl hydrocarbon receptor (AhR).

FICZ is a potent aryl agonist for the hydrocarbon receptor (AhR, Kd: 70 pM).

AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of …

Carbidopa is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE …

L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate …

Tapinarof is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.

PDM 11 is an antagonist of aryl hydrocarbon receptor (AhR)

ITE is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) (Ki : 3 nM), …

1,4-Chrysenequinone is an activator of aryl hydrocarbon receptor (AhR).

(-)-Perillaldehyde shows antibacterial activity.