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Lipoxigenasa

Lipoxigenasa

Las lipoxigenasas son una familia de enzimas que catalizan la oxigenación de ácidos grasos poliinsaturados, llevando a la producción de mediadores lipídicos bioactivos como los leucotrienos y las lipoxinas. Estos mediadores desempeñan roles cruciales en la inflamación, las respuestas inmunitarias y el cáncer. Los inhibidores de la lipoxigenasa se utilizan para estudiar su papel en enfermedades inflamatorias, asma y cáncer. En CymitQuimica, ofrecemos una variedad de inhibidores de lipoxigenasa para apoyar su investigación en inflamación, oncología y metabolismo de los lípidos.

Se han encontrado 124 productos de "Lipoxigenasa"

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  • Meclofenoxate hydrochloride

    CAS:
    <p>Meclofenoxate HCl (Lucidril) boosts memory and cognition; it's a DIMETHYLAMINOETHANOL and p-chlorophenoxyacetic acid ester.</p>
    Fórmula:C12H16ClNO3·HCl
    Pureza:97.05%
    Forma y color:White Crystal Powder
    Peso molecular:294.17
  • Diethylcarbamazine citrate

    CAS:
    <p>Diethylcarbamazine citrate treats filariasis, targeting W. bancrofti and L. loa by inhibiting arachidonic acid in microfilaria.</p>
    Fórmula:C10H21N3O·C6H8O7
    Pureza:99.61%
    Forma y color:White Crystalline Powder And Animals (Epa 1998)
    Peso molecular:391.42
  • Zileuton

    CAS:
    <p>Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.</p>
    Fórmula:C11H12N2O2S
    Pureza:98.72% - 99.43%
    Forma y color:Crystalline Solid
    Peso molecular:236.29
  • Lagunamycin

    CAS:
    <p>Lagunamycin is used as a novel 5-lipoxygenase inhibitor.</p>
    Fórmula:C19H21N3O4
    Forma y color:Solid
    Peso molecular:355.39
  • Damnacanthol


    <p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>
    Fórmula:C16H12O5
    Forma y color:Solid
    Peso molecular:284.267
  • 13-epi-12-oxo Phytodienoic Acid

    CAS:
    <p>13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.</p>
    Fórmula:C18H28O3
    Forma y color:Solid
    Peso molecular:292.41
  • DKI5

    CAS:
    <p>DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.</p>
    Fórmula:C8H10N4S
    Pureza:98%
    Forma y color:Soild
    Peso molecular:194.26
  • 15-LOX-1 inhibitor 1

    CAS:
    <p>9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, &amp; cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.</p>
    Fórmula:C22H21ClN2O4
    Forma y color:Solid
    Peso molecular:412.87
  • (-)-Dihydroguaiaretic acid


    <p>(-)-Dihydroguaiaretic acid is a useful organic compound for research related to life sciences and the catalog number is T126154.</p>
    Fórmula:C20H26O4
    Forma y color:Solid
    Peso molecular:330.424
  • 1-Naphthyl 3,5-dinitrobenzoate

    CAS:
    <p>1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.</p>
    Fórmula:C17H10N2O6
    Pureza:99.79%
    Forma y color:Solid
    Peso molecular:338.27
  • ZD-2138

    CAS:
    <p>ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.</p>
    Fórmula:C23H24FNO4
    Pureza:99.68% - >99.99%
    Forma y color:Solid
    Peso molecular:397.44
  • Ruthenoleuton


    <p>Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.</p>
    Fórmula:C13H16N2O2Ru
    Forma y color:Solid
    Peso molecular:333.35
  • E 6080 HCl

    CAS:
    <p>E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.</p>
    Fórmula:C17H20ClN3O3S2
    Pureza:99.80%
    Forma y color:Soild
    Peso molecular:413.94
  • 5-Lipoxygenase-IN-3

    CAS:
    <p>Compound 14, a &lt;1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.</p>
    Fórmula:C19H16ClN5O
    Forma y color:Solid
    Peso molecular:365.82
  • CBS-1114 HCl

    CAS:
    <p>CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.</p>
    Fórmula:C13H14ClN3
    Pureza:99.36%
    Forma y color:Soild
    Peso molecular:247.72
  • CMI977

    CAS:
    <p>CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).</p>
    Fórmula:C16H19FN2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:322.33
  • (±)15-HEDE

    CAS:
    <p>(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.</p>
    Fórmula:C20H36O3
    Forma y color:Solid
    Peso molecular:324.505
  • h15-LOX-2 inhibitor 2


    <p>Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.</p>
    Fórmula:C22H30Cl2N6O3
    Forma y color:Solid
    Peso molecular:497.42
  • KKII5

    CAS:
    <p>KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of</p>
    Fórmula:C16H14N2S
    Pureza:99.34%
    Forma y color:Solid
    Peso molecular:266.36
  • Caffeoylcalleryanin

    CAS:
    <p>Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.</p>
    Fórmula:C22H24O11
    Forma y color:Solid
    Peso molecular:464.4