Lipoxigenasa
Las lipoxigenasas son una familia de enzimas que catalizan la oxigenación de ácidos grasos poliinsaturados, llevando a la producción de mediadores lipídicos bioactivos como los leucotrienos y las lipoxinas. Estos mediadores desempeñan roles cruciales en la inflamación, las respuestas inmunitarias y el cáncer. Los inhibidores de la lipoxigenasa se utilizan para estudiar su papel en enfermedades inflamatorias, asma y cáncer. En CymitQuimica, ofrecemos una variedad de inhibidores de lipoxigenasa para apoyar su investigación en inflamación, oncología y metabolismo de los lípidos.
Se han encontrado 151 productos para "Lipoxigenasa".
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ThioLox
CAS:ThioLox, a 15-LOX-1 inhibitor (IC50: 12 μM), has anti-inflammatory, neuroprotective benefits, and guards against glutamate toxicity.Fórmula:C15H18N2OSPureza:99.98%Forma y color:SolidPeso molecular:274.381Zileuton
CAS:Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Fórmula:C11H12N2O2SPureza:98.72% - 99.86%Forma y color:White SolidPeso molecular:236.295-LOX/NO-IN-1
5-LOX/NO-IN-1 (Compound 7e) is a dual inhibitor of 5-LOX and nitric oxide release. It exhibits an IC50 value of 2.833 μM for 5-LOX and demonstrates anti-inflammatory properties.Fórmula:C22H18N6O4Forma y color:SolidPeso molecular:430.4215-LOX-1 inhibitor 1
CAS:9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.Fórmula:C22H21ClN2O4Forma y color:SolidPeso molecular:412.866mPGES-1/5-LOX-IN-1
mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.Fórmula:C20H22N4O6SForma y color:SolidPeso molecular:446.12601Myxochelin A
CAS:Myxochelin A from A. disciformis fights Gram-positive bacteria, inhibits 5-LO with IC50 of 1.9 μM, and is cytotoxic to colon cancer cells.Fórmula:C20H24N2O7Forma y color:SolidPeso molecular:404.419CMI977
CAS:CMI977 is a potent inhibitor of 5-Lipoxygenase (5-LO).Fórmula:C16H19FN2O4Pureza:98%Forma y color:SolidPeso molecular:322.33KKII5
CAS:KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers ofFórmula:C16H14N2SPureza:99.44%Forma y color:SolidPeso molecular:266.361h15-LOX-2 inhibitor 2
Compound 10 (h15-LOX-2 inhibitor 2) suppresses h15-LOX activity, exhibiting IC 50 and K i values of 26.9 μM and 16.4 μM, respectively.Fórmula:C22H30Cl2N6O3Forma y color:SolidPeso molecular:497.42DKI5
CAS:DKI5, a LOX-1 inhibitor with 22.5 μM IC50, may exhibit anti-inflammatory, antioxidant, and anti-lipid peroxidation effects in vitro.Fórmula:C8H10N4SPureza:97.08%Forma y color:White SolidPeso molecular:194.26CBS-1114 HCl
CAS:CBS-1114 HCl: 5-lipoxygenase inhibitor, anti-inflammatory, improves heart function, reduces heart's fat.Fórmula:C13H14ClN3Pureza:99.93%Forma y color:SoildPeso molecular:247.7231-Naphthyl 3,5-dinitrobenzoate
CAS:1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.Fórmula:C17H10N2O6Pureza:99.79%Forma y color:SolidPeso molecular:338.2711Lagunamycin
CAS:Lagunamycin is used as a novel 5-lipoxygenase inhibitor.Fórmula:C19H21N3O4Forma y color:SolidPeso molecular:355.3913-epi-12-oxo Phytodienoic Acid
CAS:13-epi-12-oxo PDA is a lipoxygenase derivative of α-linolenic acid in green plant leaves, often isomerizing during extraction and storage.Fórmula:C18H28O3Forma y color:SolidPeso molecular:292.41E 6080 HCl
CAS:E 6080 HCl is a 5-lipoxygenase inhibitor and can be used to study bronchial diseases.Fórmula:C17H20ClN3O3S2Pureza:99.78%Forma y color:White SolidPeso molecular:413.945-Lipoxygenase-IN-3
CAS:Compound 14, a <1 μM 5-lipoxygenase inhibitor, researches inflammation, cancer, stroke, Alzheimer's.Fórmula:C19H16ClN5OForma y color:SolidPeso molecular:365.82(±)15-HEDE
CAS:(±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.Fórmula:C20H36O3Forma y color:SolidPeso molecular:324.505Ruthenoleuton
Ruthenoleuton is a 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 3.49 μM and a Ki of 0.80 μM. It possesses antioxidant properties and is applicable in research on inflammatory diseases.Fórmula:C13H16N2O2RuForma y color:SolidPeso molecular:333.35ZD-2138
CAS:ZD-2138: Selective 5-LOX inhibitor, eases allergen-induced asthma attacks and airway constriction in guinea pigs.Fórmula:C23H24FNO4Pureza:99.68% - >99.99%Forma y color:SolidPeso molecular:397.4394BLX3887
CAS:BLX3887 selectively inhibits 15-LO-1 (IC50 = 32 nM), not 15-LO-2, less on 5-LO/12-LO, and affects eosinophils and dendritic cells.Fórmula:C10H5Cl3FN3OForma y color:White SolidPeso molecular:308.52
