Beta amiloide
Beta amyloid inhibitors are compounds that specifically target and inhibit the formation or aggregation of beta-amyloid peptides, which are critically involved in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is one of the key pathological features of Alzheimer's, contributing to neuronal dysfunction, synaptic loss, and cognitive decline. By preventing the aggregation of beta-amyloid, these inhibitors are being actively researched as potential therapeutic agents aimed at slowing down or even halting the progression of Alzheimer's disease. At CymitQuimica, we offer a variety of high-quality beta-amyloid inhibitors to support your research in neurodegenerative disorders, protein aggregation, and the development of Alzheimer's therapies.
Se han encontrado 221 productos de "Beta amiloide"
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BI-1408
CAS:BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).Fórmula:C22H23FN6Pureza:99.63%Forma y color:SolidPeso molecular:390.46amyloid P-IN-1
CAS:amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, andFórmula:C30H44N2O14Pureza:99.76%Forma y color:SolidPeso molecular:656.68MAO-B-IN-9
CAS:MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.
Fórmula:C18H24N2O2Pureza:99.93%Forma y color:SolidPeso molecular:300.4Fenlean
CAS:"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."Fórmula:C26H27NO6Pureza:98.99%Forma y color:SolidPeso molecular:449.5Ref: TM-T31773
1mg73,00€2mg98,00€5mg165,00€10mg295,00€25mg532,00€50mg800,00€100mg954,00€200mg1.288,00€BMS 433796
CAS:BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer's disease.
Fórmula:C21H20F2N4O4Pureza:99.17%Forma y color:SolidPeso molecular:430.4NNC 26-9100
CAS:Somatostatin sst4 receptor agonistFórmula:C22H25BrCl2N6SPureza:98%Forma y color:SolidPeso molecular:556.35Aβ/tau aggregation-IN-3
CAS:Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functionalFórmula:C23H22N4O3Forma y color:SolidPeso molecular:402.45QM-FN-SO3
CAS:QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].Fórmula:C29H25N4NaO3S2Forma y color:SolidPeso molecular:564.65RAGE/SERT-IN-1
CAS:RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM andFórmula:C38H41ClN4OSForma y color:SolidPeso molecular:637.28Anti-amyloid agent-1
CAS:Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].Fórmula:C21H17F3N2O3Forma y color:SolidPeso molecular:402.37QR-0217
CAS:QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.Fórmula:C19H13NO3Forma y color:SolidPeso molecular:303.31ELND007
CAS:ELND007 is a Gamma secretase inhibitor.Fórmula:C19H14F4N4O2SForma y color:SolidPeso molecular:438.4PQM130
CAS:PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.Fórmula:C23H27NO4Pureza:98.73%Forma y color:SolidPeso molecular:381.46TRV-1387
CAS:TRV-1387, a benzofurazan derivative, inhibits the aggregation of tau and amyloid-β [1].Fórmula:C23H25F3N4O2Forma y color:SolidPeso molecular:446.47rTRD01
CAS:rTRD01 is a TDP-43 ligand that selectively binds to the RRM1 and RRM2 domains of TDP-43, exhibiting a dissociation constant (Kd) of 89 µM for TDP-43 102–269.Fórmula:C18H21FN4O2Forma y color:SolidPeso molecular:344.38γ-Secretase-IN-1
CAS:γ-Secretase-IN-1 is a γ-secretase inhibitor that displays partial antiproliferative activity against T-47D cells.Fórmula:C27H24F2N4O3Pureza:99.56%Forma y color:SolidPeso molecular:490.5Ref: TM-T3521
1mg120,00€5mg385,00€10mg618,00€25mg1.224,00€50mg1.648,00€100mg2.232,00€1mL*10mM (DMSO)416,00€MDR-1339
CAS:MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.Fórmula:C20H22O4Pureza:98.57%Forma y color:SolidPeso molecular:326.39Antioxidant agent-8
Antioxidant agent-8, an oral Aβ 1-42 inhibitor, reduces fibril aggregation & promotes disaggregation; it's neuroprotective & BBB permeable.Fórmula:C13H12O5Forma y color:SolidPeso molecular:248.232002-G12
CAS:2002-G12 (compound 5a) is an Aβ42 inhibitor that can reduce Aβ42 toxicity by 76%. It is applicable in Alzheimer's research.Fórmula:C20H16N6Forma y color:SolidPeso molecular:340.381γ-secretase modulator 5
Compound 22d is a GSM that crosses the blood-brain barrier, inhibits Aβ42 production (IC50: 60 nM), and may help study Alzheimer's.Forma y color:Solid
