Beta amiloide
Beta amyloid inhibitors are compounds that specifically target and inhibit the formation or aggregation of beta-amyloid peptides, which are critically involved in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is one of the key pathological features of Alzheimer's, contributing to neuronal dysfunction, synaptic loss, and cognitive decline. By preventing the aggregation of beta-amyloid, these inhibitors are being actively researched as potential therapeutic agents aimed at slowing down or even halting the progression of Alzheimer's disease. At CymitQuimica, we offer a variety of high-quality beta-amyloid inhibitors to support your research in neurodegenerative disorders, protein aggregation, and the development of Alzheimer's therapies.
Se han encontrado 220 productos de "Beta amiloide"
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BuChE-IN-2
CAS:BuChE-IN-2 inhibits BuChE (IC50: 1.28 μM), NO (0.67 μM), Aβ, ROS, chelates Cu2+, penetrates BBB, used in Alzheimer's research.Fórmula:C28H20F4N6O3Forma y color:SolidPeso molecular:564.49TC-E 5006
CAS:γ-secretase modulatorFórmula:C29H29F4NO2Pureza:98%Forma y color:SolidPeso molecular:499.54q-FTAA
CAS:q-FTAA targets Aβ1-42 fibrils (330-630 nM) and ADPBC (300-500 nM), useful in Alzheimer's disease research.Fórmula:C21H14O6S4Forma y color:SolidPeso molecular:490.59JNJ-40418677
CAS:JNJ-40418677 is a γ-secretase modulator that selectively blocks γ-site cleavage of the APP without affecting the processing of Notch.Fórmula:C26H22F6O2Pureza:98%Forma y color:SolidPeso molecular:480.44OAB-14
CAS:OAB-14, a Bexarotene derivative, enhances β-amyloid clearance and cognitive function in APP/PS1 mice, improving Alzheimer's symptoms.Fórmula:C32H46N4O2Forma y color:SolidPeso molecular:518.73LC kinetic stabilizer-2
CAS:LC Kinetic Stabilizer-2 is a powerful stabilizer for amyloidogenic immunoglobulin light chains (LC), demonstrating significant efficacy with an EC50 of 24 nM.Fórmula:C28H31N3O3Forma y color:SolidPeso molecular:457.56YIAD-0205
CAS:YIAD-0205, an orally administered inhibitor of Aβ(1-42) aggregation, has exhibited in vivo efficacy in a 5XFAD transgenic mouse model that harbors five familialFórmula:C26H16Br2ClN3Forma y color:SolidPeso molecular:565.69Glutaminyl Cyclase Inhibitor 5
Glutaminyl Cyclase Inhibitor 5 is a potent, selective inhibitor of human glutaminyl cyclase (hQC), demonstrating an inhibition concentration half-max (IC 50) ofFórmula:C22H30N6OForma y color:SolidPeso molecular:394.51AY1511
CAS:AY1511 is a low cytotoxic inhibitor of amyloid β (Aβ) aggregation [1].Fórmula:C17H14O6Forma y color:SolidPeso molecular:314.29BTA-1
CAS:BTA-1 is an uncharged derivative of thioflavin-T that has high affinity for Aβ fibrils and shows very good brain entry and clearance [1].Fórmula:C14H12N2SForma y color:SolidPeso molecular:240.32THK-523
CAS:THK-523 selectively binds to tau in Alzheimer's, potent in vitro/vivo. 18F-THK523 excels in tau imaging.Fórmula:C17H15FN2OForma y color:SolidPeso molecular:282.31TML-6
CAS:TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.Fórmula:C30H37NO7Pureza:99.71%Forma y color:SolidPeso molecular:523.62Ref: TM-T37148
1mg94,00€5mg222,00€10mg356,00€25mg708,00€50mg1.063,00€100mg1.674,00€1mL*10mM (DMSO)256,00€ELND006
CAS:ELND006, an oral Alzheimer's drug, has improved bioavailability as a nanosuspension, and food doesn't affect it.Fórmula:C20H14F5N3O2SForma y color:SolidPeso molecular:455.4BI-1408
CAS:BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).Fórmula:C22H23FN6Pureza:99.63%Forma y color:SolidPeso molecular:390.46MK-3328
CAS:MK-3328, a potential Alzheimer's drug, binds β-Amyloid with strong affinity (IC50:10.5 nM) and may serve as a PET ligand to gauge plaque load.
Fórmula:C14H9FN4OPureza:99.70% - >99.99%Forma y color:SolidPeso molecular:268.25Ref: TM-T16094
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€MAO-B-IN-9
CAS:MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.
Fórmula:C18H24N2O2Pureza:99.93%Forma y color:SolidPeso molecular:300.4Glutaminyl Cyclase Inhibitor 1
CAS:Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor (IC50: 0.5 μM) that can be used to study neurological disorders.Fórmula:C21H24FN3O2Pureza:99.81%Forma y color:SolidPeso molecular:369.43amyloid P-IN-1
CAS:amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, andFórmula:C30H44N2O14Pureza:99.76%Forma y color:SolidPeso molecular:656.68Aleplasinin
CAS:Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolyticFórmula:C28H27NO3Pureza:99.21%Forma y color:SolidPeso molecular:425.52Ref: TM-T29856
1mg57,00€5mg120,00€10mg188,00€25mg432,00€50mg655,00€100mg1.035,00€200mg1.388,00€1mL*10mM (DMSO)133,00€Ezeprogind disulfate
CAS:Ezeprogind disulfate: neurotrophic inducer targeting neurodegeneration causes like Abeta, tau; for neurological disorder research.Fórmula:C25H48N6O8S2Pureza:99.72%Forma y color:SolidPeso molecular:624.81
