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GluR

GluR

Inhibidores del Receptor de Glutamato son compuestos que bloquean la actividad de los receptores de glutamato, los principales receptores de neurotransmisores excitatorios en el cerebro. Estos receptores desempeñan un papel crucial en la transmisión sináptica, la plasticidad, el aprendizaje y la memoria. La desregulación de la señalización de glutamato está asociada con varios trastornos neurológicos, como la epilepsia, el accidente cerebrovascular y las enfermedades neurodegenerativas. Los inhibidores de los receptores de glutamato son esenciales para investigar los mecanismos de la excitotoxicidad y desarrollar estrategias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de receptores de glutamato para apoyar su investigación en la función sináptica, la neuroprotección y los trastornos cognitivos.

Se han encontrado 265 productos de "GluR"

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  • Basimglurant

    CAS:
    Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).
    Fórmula:C18H13ClFN3
    Pureza:98.35%
    Forma y color:Solid
    Peso molecular:325.77

    Ref: TM-T12717

    1mg
    71,00€
    5mg
    152,00€
    10mg
    222,00€
    25mg
    358,00€
    50mg
    532,00€
    100mg
    665,00€
    200mg
    898,00€
    1mL*10mM (DMSO)
    167,00€
  • Decoglurant

    CAS:
    Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.
    Fórmula:C21H11F6N5
    Pureza:99.77%
    Forma y color:Solid
    Peso molecular:447.34

    Ref: TM-T15090

    1mg
    52,00€
    5mg
    111,00€
    10mg
    164,00€
    25mg
    294,00€
    50mg
    411,00€
    100mg
    572,00€
    200mg
    772,00€
    1mL*10mM (DMSO)
    152,00€
  • VU0650786

    CAS:
    VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.
    Fórmula:C18H15ClFN5O2
    Pureza:99.09%
    Forma y color:Solid
    Peso molecular:387.8

    Ref: TM-T13318

    1mg
    90,00€
    5mg
    222,00€
    10mg
    313,00€
    25mg
    530,00€
    50mg
    757,00€
    100mg
    1.044,00€
    1mL*10mM (DMSO)
    245,00€
  • DHPG

    CAS:
    DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.
    Fórmula:C8H9NO4
    Pureza:99.55%
    Forma y color:Solid
    Peso molecular:183.16

    Ref: TM-T11032

    5mg
    50,00€
    10mg
    74,00€
    25mg
    125,00€
    50mg
    220,00€
  • Org-26576

    CAS:
    Org-26576 is a positive allosteric modulator of the AMPA receptor.
    Fórmula:C11H12N2O2
    Pureza:99.67%
    Forma y color:Solid
    Peso molecular:204.23

    Ref: TM-T16402

    5mg
    44,00€
    10mg
    66,00€
    25mg
    99,00€
    50mg
    142,00€
    100mg
    244,00€
    200mg
    359,00€
    1mL*10mM (DMSO)
    48,00€
  • LY339434 HCl


    LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)
    Fórmula:C18H20ClNO4
    Pureza:97.10% - 97.19%
    Forma y color:Soild
    Peso molecular:349.81

    Ref: TM-T27947L

    1mg
    175,00€
    5mg
    388,00€
    10mg
    572,00€
    25mg
    888,00€
    50mg
    1.224,00€
    100mg
    1.648,00€
    500mg
    3.312,00€
  • Piracetam

    CAS:
    Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.
    Fórmula:C6H10N2O2
    Pureza:97.16%
    Forma y color:Crystals From Isopropanol Solid
    Peso molecular:142.16

    Ref: TM-T0426

    1g
    34,00€
    1mL*10mM (DMSO)
    52,00€
  • γ-DGG acetate(6729-55-1 free base)

    CAS:
    gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.
    Fórmula:C9H16N2O7
    Pureza:99.81%
    Forma y color:Solid
    Peso molecular:264.23

    Ref: TM-T15369L

    25mg
    44,00€
    50mg
    50,00€
  • (R)-ADX-47273

    CAS:

    (R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).

    Fórmula:C20H17F2N3O2
    Pureza:99.87%
    Forma y color:Solid
    Peso molecular:369.36

    Ref: TM-T13441

    2mg
    42,00€
    5mg
    65,00€
    10mg
    94,00€
    25mg
    170,00€
    50mg
    259,00€
    100mg
    391,00€
    200mg
    545,00€
  • (R)-3,4-DCPG HCl


    (R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal

    Fórmula:C10H10ClNO6
    Pureza:98.80% - 99.89%
    Forma y color:Soild
    Peso molecular:275.64

    Ref: TM-T23215L

    1mg
    115,00€
    5mg
    250,00€
    10mg
    369,00€
    25mg
    562,00€
  • AZD-8529 mesylate

    CAS:
    AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).
    Fórmula:C25H28F3N5O6S
    Pureza:99.19%
    Forma y color:Solid
    Peso molecular:583.58

    Ref: TM-T10432L

    1mg
    57,00€
    5mg
    120,00€
    10mg
    188,00€
    25mg
    432,00€
    50mg
    747,00€
    100mg
    1.093,00€
    200mg
    1.454,00€
    1mL*10mM (DMSO)
    156,00€
  • KM02894

    CAS:
    KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.
    Fórmula:C7H9N3OS2
    Pureza:99.98%
    Forma y color:Solid
    Peso molecular:215.3

    Ref: TM-T77581

    25mg
    34,00€
  • NBQX disodium

    CAS:
    NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.
    Fórmula:C12H6N4Na2O6S
    Pureza:97.32% - 97.6%
    Forma y color:Solid
    Peso molecular:380.2415

    Ref: TM-T25853

    1mg
    42,00€
    5mg
    88,00€
    10mg
    120,00€
    25mg
    235,00€
    50mg
    354,00€
    100mg
    530,00€
    1mL*10mM (DMSO)
    96,00€
  • LY3027788

    CAS:
    LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.
    Fórmula:C25H31F2NO11S
    Forma y color:Solid
    Peso molecular:591.58

    Ref: TM-T38792

    5mg
    873,00€
  • LY3027788 hydrochloride

    CAS:
    LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.
    Fórmula:C25H32ClF2NO11S
    Forma y color:Solid
    Peso molecular:628.03

    Ref: TM-T38790

    5mg
    873,00€
  • LY2812223

    CAS:
    LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).
    Fórmula:C10H12N4O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:284.29

    Ref: TM-T15809

    25mg
    A consultar
    50mg
    A consultar
    100mg
    A consultar
  • ML353


    ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.
    Fórmula:C19H15FN2O
    Pureza:99.98% - 99.98%
    Forma y color:Soild
    Peso molecular:306.33

    Ref: TM-T67917

    5mg
    49,00€
    10mg
    79,00€
    25mg
    120,00€
    50mg
    164,00€
    100mg
    230,00€
    200mg
    314,00€
    1mL*10mM (DMSO)
    52,00€
  • GYKI-47261 dihydrochloride

    CAS:
    GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.
    Fórmula:C18H17Cl3N4
    Pureza:98.32% - 99.14%
    Forma y color:Solid
    Peso molecular:395.71

    Ref: TM-T38601

    1mg
    285,00€
    5mg
    689,00€
    10mg
    947,00€
    25mg
    1.458,00€
  • mGluR5 modulator 1

    CAS:
    mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.
    Fórmula:C18H19ClFN3O2
    Forma y color:Solid
    Peso molecular:363.82

    Ref: TM-T38659

    5mg
    922,00€
  • JF-NP-26


    Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.
    Forma y color:Solid

    Ref: TM-T38229

    5mg
    359,00€