
GluR
Inhibidores del Receptor de Glutamato son compuestos que bloquean la actividad de los receptores de glutamato, los principales receptores de neurotransmisores excitatorios en el cerebro. Estos receptores desempeñan un papel crucial en la transmisión sináptica, la plasticidad, el aprendizaje y la memoria. La desregulación de la señalización de glutamato está asociada con varios trastornos neurológicos, como la epilepsia, el accidente cerebrovascular y las enfermedades neurodegenerativas. Los inhibidores de los receptores de glutamato son esenciales para investigar los mecanismos de la excitotoxicidad y desarrollar estrategias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de receptores de glutamato para apoyar su investigación en la función sináptica, la neuroprotección y los trastornos cognitivos.
Se han encontrado 255 productos de "GluR"
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LSP1-2111
CAS:<p>LSP1-2111 is a mGlu4 receptor subtype agonist.</p>Fórmula:C12H17N2O9PForma y color:SolidPeso molecular:364.25Lu-AF11205
CAS:<p>Lu-AF11205 is a potent positive allosteric modulator (PAM) of mGlu5 receptor.</p>Fórmula:C17H16N2OSPureza:98%Forma y color:SolidPeso molecular:296.39(RS)-4-Carboxyphenylglycine
CAS:<p>(RS)-4-Carboxyphenylglycine is a racemic mixture. (S)-4-Carboxyphenylglycine is a selective mGlu1α receptor antagonist.</p>Fórmula:C9H9NO4Pureza:99.04% - >99.99%Forma y color:SolidPeso molecular:195.17(R)-4-Carboxyphenylglycine
CAS:<p>(R)-4-Carboxyphenylglycine is a NMDA receptor antagonist.</p>Fórmula:C9H9NO4Pureza:98%Forma y color:SolidPeso molecular:195.17VU0652835
CAS:<p>VU0652835 is a negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGlu5) (IC50: 81 nM).</p>Fórmula:C16H19N3O3SPureza:98%Forma y color:SolidPeso molecular:333.41JNJ-55511118
CAS:<p>JNJ-55511118 is a TARP γ8 allosteric modulator with anticonvulsant activity, which can be used in research on chronic operant alcohol self-administration.</p>Fórmula:C14H8ClF3N2O2Forma y color:SolidPeso molecular:328.67DCB
CAS:<p>DCB is an mGluR5 allosteric ligand that blocks mGluR modulation, countering DMeOB and DFB effects.</p>Fórmula:C14H10Cl2N2Pureza:99.12% - 99.9%Forma y color:SolidPeso molecular:277.15ML337
CAS:<p>ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.</p>Fórmula:C21H20FNO3Pureza:99.83%Forma y color:SolidPeso molecular:353.39LY382884
CAS:<p>LY382884 is a selective and potent GluR5 kainate receptor antagonist with anxiolytic activity.LY382884 blocks blockade of mossy fibre LTP induction.</p>Fórmula:C18H23NO4Pureza:98.32% - 98.71%Forma y color:SolidPeso molecular:317.38TC-N 22A
CAS:<p>TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier.</p>Fórmula:C14H13N5SPureza:99.95%Forma y color:SolidPeso molecular:283.35CPPHA
CAS:<p>CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.</p>Fórmula:C22H15ClN2O4Pureza:98.07%Forma y color:SolidPeso molecular:406.82ML289
CAS:<p>ML289 is a potent CNS-penetrant mGlu3 modulator with IC50 of 0.66 μM, >15-fold selectivity over mGlu2, and inactive against mGlu5.</p>Fórmula:C22H23NO3Pureza:99.54%Forma y color:SolidPeso molecular:349.42Foliglurax
CAS:<p>Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).</p>Fórmula:C23H23N3O3SPureza:98%Forma y color:SolidPeso molecular:421.51VU6001376
CAS:<p>VU6001376 is an effective and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (EC50: 50.1 nM).</p>Fórmula:C18H14F2N6OSPureza:98%Forma y color:SolidPeso molecular:400.41Ro 67-4853
CAS:<p>Ro 67-4853 is a positive allosteric modulator of mGluR1, selectively enhancing the response to the agonist (S)-3,5-dihydroxy-phenylglycine (DHPG).</p>Fórmula:C19H19NO4Pureza:98.57%Forma y color:SolidPeso molecular:325.36VU0155041 sodium
CAS:<p>VU0155041 sodium is a positive allosteric modulator of mGluR4 that promotes extinction in male rats.</p>Fórmula:C14H14Cl2NNaO3Pureza:98%Forma y color:SolidPeso molecular:338.16HexylHIBO
CAS:<p>HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.</p>Fórmula:C12H20N2O4Pureza:99.55%Forma y color:SolidPeso molecular:256.3(S)-MCPG
CAS:<p>(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.</p>Fórmula:C10H11NO4Pureza:98.72%Forma y color:SolidPeso molecular:209.20DMeOB
CAS:<p>DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.</p>Fórmula:C16H16N2O2Pureza:98.34%Forma y color:SolidPeso molecular:268.31A-794282
CAS:<p>A-794282 is a selective antagonist of mGluR1.</p>Fórmula:C19H18N4OSPureza:99.87%Forma y color:SolidPeso molecular:350.44
