
GluR
Inhibidores del Receptor de Glutamato son compuestos que bloquean la actividad de los receptores de glutamato, los principales receptores de neurotransmisores excitatorios en el cerebro. Estos receptores desempeñan un papel crucial en la transmisión sináptica, la plasticidad, el aprendizaje y la memoria. La desregulación de la señalización de glutamato está asociada con varios trastornos neurológicos, como la epilepsia, el accidente cerebrovascular y las enfermedades neurodegenerativas. Los inhibidores de los receptores de glutamato son esenciales para investigar los mecanismos de la excitotoxicidad y desarrollar estrategias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de receptores de glutamato para apoyar su investigación en la función sináptica, la neuroprotección y los trastornos cognitivos.
Se han encontrado 265 productos de "GluR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Foliglurax
CAS:Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).Fórmula:C23H23N3O3SPureza:98%Forma y color:SolidPeso molecular:421.51VU6001376
CAS:VU6001376 is an effective and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (EC50: 50.1 nM).Fórmula:C18H14F2N6OSPureza:98%Forma y color:SolidPeso molecular:400.41LY392098
CAS:LY392098 (AMPA receptor modulator-3) is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.Fórmula:C18H22FNO2SPureza:99.86%Forma y color:SolidPeso molecular:335.44Ref: TM-T27951
1mg39,00€5mg93,00€1mL*10mM (DMSO)96,00€10mg133,00€25mg215,00€50mg306,00€100mg414,00€200mg573,00€NS 1209
CAS:NS 1209 (SPD 502) is a AMPA receptor antagonist.Fórmula:C24H27N4NaO7SPureza:98%Forma y color:SolidPeso molecular:538.55Ro 67-4853
CAS:Ro 67-4853 is a positive allosteric modulator of mGluR1, selectively enhancing the response to the agonist (S)-3,5-dihydroxy-phenylglycine (DHPG).Fórmula:C19H19NO4Pureza:98.57%Forma y color:SolidPeso molecular:325.36VU0155041 sodium
CAS:VU0155041 sodium is a positive allosteric modulator of mGluR4 that promotes extinction in male rats.Fórmula:C14H14Cl2NNaO3Pureza:98%Forma y color:SolidPeso molecular:338.16HexylHIBO
CAS:HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.Fórmula:C12H20N2O4Pureza:99.55%Forma y color:SolidPeso molecular:256.3(S)-MCPG
CAS:(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.Fórmula:C10H11NO4Pureza:98.72%Forma y color:SolidPeso molecular:209.20MFZ 10-7 hydrochloride
CAS:MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAMFórmula:C15H10ClFN2Pureza:98%Forma y color:SolidPeso molecular:272.71DMeOB
CAS:DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.Fórmula:C16H16N2O2Pureza:98.34%Forma y color:SolidPeso molecular:268.31BMT-145027
CAS:BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 nM).Fórmula:C23H14ClF3N4Pureza:99.62%Forma y color:SolidPeso molecular:438.83A-794282
CAS:A-794282 is a selective antagonist of mGluR1.Fórmula:C19H18N4OSPureza:99.87%Forma y color:SolidPeso molecular:350.44(RS)-4-Carboxy-3-hydroxyphenylglycine
CAS:broad spectrum EAA agonist/antagonistFórmula:C9H9NO5Pureza:98%Forma y color:SolidPeso molecular:211.17Ro4491533
CAS:Ro4491533 is a potent and selective negative allosteric modulator for group II of the metabotropic glutamate receptors (mGluR2/3).Fórmula:C24H20F3N3OForma y color:SolidPeso molecular:423.43MMPIP
CAS:allosteric mGlu7-selective receptor antagonistFórmula:C19H15N3O3Pureza:98%Forma y color:SolidPeso molecular:333.34LSP4-2022
CAS:LSP4-2022, a mGlu4 selective agonist, increases behavioral despair in mouse models of antidepressant action.Fórmula:C13H18NO8PPureza:100%Forma y color:SolidPeso molecular:347.26VU0409106
CAS:VU0409106 is a potent, mGlu5-selective inhibitor.Fórmula:C15H11FN4O2SPureza:98%Forma y color:SolidPeso molecular:330.34Remeglurant
CAS:Remeglurant is used as a selective antagonist of the mGlu5 receptor.Fórmula:C17H15BrN4OForma y color:SolidPeso molecular:371.23IEM 1925 dihydrobromide
CAS:AMPA receptor antagonistFórmula:C17H30Br2N2Pureza:98%Forma y color:SolidPeso molecular:422.24PHCCC(4Me)
CAS:THCCC, a PHCCC analog, is a dual metabotropic glutamate receptor 2/3 negative/positive allosteric modulator.Fórmula:C18H16N2O3Forma y color:SolidPeso molecular:308.33
