
GluR
Inhibidores del Receptor de Glutamato son compuestos que bloquean la actividad de los receptores de glutamato, los principales receptores de neurotransmisores excitatorios en el cerebro. Estos receptores desempeñan un papel crucial en la transmisión sináptica, la plasticidad, el aprendizaje y la memoria. La desregulación de la señalización de glutamato está asociada con varios trastornos neurológicos, como la epilepsia, el accidente cerebrovascular y las enfermedades neurodegenerativas. Los inhibidores de los receptores de glutamato son esenciales para investigar los mecanismos de la excitotoxicidad y desarrollar estrategias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de receptores de glutamato para apoyar su investigación en la función sináptica, la neuroprotección y los trastornos cognitivos.
Se han encontrado 265 productos de "GluR"
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Mavoglurant racemate
CAS:Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. Mavoglurant (racemate) is the racemate of mavoglurant.Fórmula:C19H23NO3Pureza:98%Forma y color:SolidPeso molecular:313.39(1S,3R)-ACPD
CAS:(1S,3R)-ACPD is a group I and II mGlu receptor agonist.Fórmula:C7H11NO4Pureza:98%Forma y color:SolidPeso molecular:173.17L-CCG-l
CAS:group II metabotropic glutamate receptor agonistFórmula:C6H9NO4Pureza:98%Forma y color:SolidPeso molecular:159.14Foliglurax monohydrochloride
CAS:Foliglurax monohydrochloride, an antiparkinsonian, is a selective brain-penetrant mGluR4 PAM with an EC50 of 79 nM.Fórmula:C23H24ClN3O3SForma y color:SolidPeso molecular:457.97Desmethyl-YM 298198
CAS:mGlu1-selective antagonistFórmula:C17H21ClN4OSPureza:98%Forma y color:SolidPeso molecular:364.89Auglurant
CAS:Auglurant is a novel and selective mGlu5 antagonist (IC50: 11 nM (rat) and an IC50: 14 nM (human)). Auglurant has an acceptable CNS penetration.Fórmula:C16H12FN5O2Forma y color:SolidPeso molecular:325.3LY-2300559
CAS:LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.Fórmula:C26H26O6Pureza:99.22%Forma y color:SolidPeso molecular:434.48Ref: TM-T27932
1mg315,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€CBiPES hydrochloride
CAS:CBiPES hydrochloride (CBiPES HCl) is an orthosteric modulator of the mGlu2 receptor and is used to study neurological disorders like epilepsy.Fórmula:C21H20ClN3O2SPureza:99.66%Forma y color:SolidPeso molecular:413.92ABP688
CAS:ABP688 is a non-competitive and selective mGluR5 antagonist(Ki = 1.7 nM). ABP688 can be used as a PET tracer for clinical imaging.Fórmula:C15H16N2OPureza:98.63%Forma y color:SolidPeso molecular:240.3CPCCOEt
CAS:CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1bFórmula:C13H13NO4Pureza:99.91%Forma y color:SolidPeso molecular:247.25AZD 9272
CAS:AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.Fórmula:C14H6F2N4OPureza:98.29%Forma y color:SolidPeso molecular:284.22(E/Z)-SIB-1893
CAS:(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893.Fórmula:C14H13NPureza:99.96%Forma y color:SolidPeso molecular:195.26AZD6538
CAS:AZD6538 is an mGluR5 negative allosteric modulator used in the study of CNS-related diseases such as Alzheimer's disease.Fórmula:C15H6FN5OPureza:98.68%Forma y color:SolidPeso molecular:291.24Dasolampanel
CAS:Dasolampanel (NGX-426) is an ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study of chronic pain disorders.Fórmula:C17H20ClN5O3Pureza:98.70%Forma y color:SolidPeso molecular:377.83MNI 137
CAS:MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.Fórmula:C15H9BrN4OPureza:97.49%Forma y color:SolidPeso molecular:341.16Troriluzole
CAS:Troriluzole is a glutamate modulator with anticancer activity and is used in the study of spinocerebellar ataxia.Fórmula:C15H16F3N5O4SPureza:97.14%Forma y color:SolidPeso molecular:419.38Ref: TM-T17174
1mg94,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg356,00€25mg655,00€50mg1.044,00€100mg1.558,00€Dipraglurant
CAS:Dipraglurant: a blood-brain permeable mGluR5 NAM, orally active, selective, IC50 = 21 nM, treats PD-LID.Fórmula:C16H12FN3Pureza:98.7%Forma y color:SolidPeso molecular:265.29Ref: TM-T15134
1mg92,00€5mg215,00€1mL*10mM (DMSO)260,00€10mg313,00€25mg685,00€50mg1.009,00€100mg1.341,00€Valiglurax
CAS:Valiglurax (VU2957), potent mGlu4 PAM, crosses blood-brain barrier, orally available; promising for Parkinson's treatment.Fórmula:C16H10F3N5Pureza:98.29%Forma y color:SolidPeso molecular:329.28LSN2463359
CAS:LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.Fórmula:C16H15N3OPureza:99.26%Forma y color:SolidPeso molecular:265.31Ref: TM-T27854
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg80,00€25mg161,00€50mg245,00€100mg363,00€200mg515,00€S 18986
CAS:S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties inFórmula:C10H12N2O2SPureza:99.64%Forma y color:SolidPeso molecular:224.28
