
GluR
Inhibidores del Receptor de Glutamato son compuestos que bloquean la actividad de los receptores de glutamato, los principales receptores de neurotransmisores excitatorios en el cerebro. Estos receptores desempeñan un papel crucial en la transmisión sináptica, la plasticidad, el aprendizaje y la memoria. La desregulación de la señalización de glutamato está asociada con varios trastornos neurológicos, como la epilepsia, el accidente cerebrovascular y las enfermedades neurodegenerativas. Los inhibidores de los receptores de glutamato son esenciales para investigar los mecanismos de la excitotoxicidad y desarrollar estrategias neuroprotectoras. En CymitQuimica, ofrecemos una gama de inhibidores de receptores de glutamato para apoyar su investigación en la función sináptica, la neuroprotección y los trastornos cognitivos.
Se han encontrado 255 productos de "GluR"
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Troriluzole
CAS:<p>Troriluzole is a glutamate modulator with anticancer activity and is used in the study of spinocerebellar ataxia.</p>Fórmula:C15H16F3N5O4SPureza:97.14%Forma y color:SolidPeso molecular:419.38Dipraglurant
CAS:<p>Dipraglurant: a blood-brain permeable mGluR5 NAM, orally active, selective, IC50 = 21 nM, treats PD-LID.</p>Fórmula:C16H12FN3Pureza:98.7%Forma y color:SolidPeso molecular:265.29LSN2463359
CAS:<p>LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.</p>Fórmula:C16H15N3OPureza:99.26%Forma y color:SolidPeso molecular:265.31(E/Z)-SIB-1893
CAS:<p>(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893.</p>Fórmula:C14H13NPureza:99.92%Forma y color:SolidPeso molecular:195.26Dasolampanel
CAS:<p>Dasolampanel (NGX-426) is an ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study of chronic pain disorders.</p>Fórmula:C17H20ClN5O3Pureza:98.70%Forma y color:SolidPeso molecular:377.83LY-2300559
CAS:<p>LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.</p>Fórmula:C26H26O6Pureza:99.51%Forma y color:SolidPeso molecular:434.48Valiglurax
CAS:<p>Valiglurax (VU2957), potent mGlu4 PAM, crosses blood-brain barrier, orally available; promising for Parkinson's treatment.</p>Fórmula:C16H10F3N5Pureza:98.29%Forma y color:SolidPeso molecular:329.28CBiPES hydrochloride
CAS:<p>CBiPES hydrochloride (CBiPES HCl) is an orthosteric modulator of the mGlu2 receptor and is used to study neurological disorders like epilepsy.</p>Fórmula:C21H20ClN3O2SPureza:99.66%Forma y color:SolidPeso molecular:413.92CPCCOEt
CAS:<p>CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1b</p>Fórmula:C13H13NO4Pureza:99.91%Forma y color:SolidPeso molecular:247.25S 18986
CAS:<p>S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors, showcasing cognitive-enhancing properties in</p>Fórmula:C10H12N2O2SPureza:99.64%Forma y color:SolidPeso molecular:224.28VU 0285683
CAS:<p>VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.</p>Fórmula:C14H7FN4OPureza:99.98%Forma y color:SolidPeso molecular:266.23ABP688
CAS:<p>ABP688 is a non-competitive and selective mGluR5 antagonist(Ki = 1.7 nM). ABP688 can be used as a PET tracer for clinical imaging.</p>Fórmula:C15H16N2OPureza:98.63%Forma y color:SolidPeso molecular:240.3AZD 9272
CAS:<p>AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.</p>Fórmula:C14H6F2N4OPureza:98.29%Forma y color:SolidPeso molecular:284.22AZD6538
CAS:<p>AZD6538 is an mGluR5 negative allosteric modulator used in the study of CNS-related diseases such as Alzheimer's disease.</p>Fórmula:C15H6FN5OPureza:98.68%Forma y color:SolidPeso molecular:291.24MNI 137
CAS:<p>MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.</p>Fórmula:C15H9BrN4OPureza:97.49%Forma y color:SolidPeso molecular:341.16VU0029251
CAS:<p>VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.</p>Fórmula:C10H11N3S2Forma y color:SolidPeso molecular:237.34MTPG
CAS:<p>Group II/group III metabotropic glutamate receptor antagonist</p>Fórmula:C10H11N5O2Pureza:98%Forma y color:SolidPeso molecular:233.23L-AP4
CAS:<p>L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).</p>Fórmula:C4H10NO5PPureza:98%Forma y color:White To Off-White Crystalline PowderPeso molecular:183.1mGluR5 antagonist-1
CAS:<p>mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].</p>Fórmula:C23H18N4O2Forma y color:SolidPeso molecular:382.41VU0360172
CAS:<p>VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).</p>Fórmula:C18H15FN2OPureza:99.56%Forma y color:SolidPeso molecular:294.32
