BACE
Los inhibidores de BACE son compuestos que tienen como objetivo la enzima Beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE), que es crucial para la producción de beta-amiloide, una proteína asociada con la formación de placas amiloides en la enfermedad de Alzheimer. Al inhibir BACE, estos compuestos buscan reducir la producción de beta-amiloide y su acumulación en el cerebro, lo que podría ralentizar la progresión de la enfermedad de Alzheimer. Los inhibidores de BACE son un enfoque principal en el desarrollo de estrategias terapéuticas para las enfermedades neurodegenerativas. En CymitQuimica, ofrecemos inhibidores de BACE para apoyar su investigación en la enfermedad de Alzheimer, la biología amiloide y la neurodegeneración.
Se han encontrado 37 productos de "BACE"
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Elenbecestat
CAS:Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.Fórmula:C19H18F3N5O2SPureza:99.95%Forma y color:SolidPeso molecular:437.44Ref: TM-T11175
1mg66,00€5mg144,00€10mg236,00€25mg492,00€50mg710,00€100mg973,00€1mL*10mM (DMSO)158,00€BACE1 Protein, Human, Recombinant (hFc)
BACE1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:75.2 kDa (predicted, pro-form); 72.6 kDa (predicted, mature-form); 85-100 kDa (reducing condition, due to glycosylation)Ref: TM-TMPY-00651
1mg4.207,00€5µg77,00€10µg109,00€20µg174,00€50µg350,00€100µg668,00€200µg1.017,00€500µg2.071,00€Anti-BACE1 Antibody-FITC (8D358)
Anti-BACE1 Antibody-FITC (8D358) is a FITC-conjugated Rabbit antibody targeting BACE1. Anti-BACE1 Antibody-FITC (8D358) can be used in FCM.Forma y color:Odour LiquidAnti-BACE1 Antibody-PE (8D358)
Anti-BACE1 Antibody-PE (8D358) is a PE-conjugated Rabbit antibody targeting BACE1. Anti-BACE1 Antibody-PE (8D358) can be used in FCM.Forma y color:Odour LiquidAnti-BACE1 Antibody (2Z488)
Anti-BACE1 Antibody (2Z488) is a Mouse antibody targeting BACE1. Anti-BACE1 Antibody (2Z488) can be used in ELISA.Forma y color:Odour LiquidAnti-BACE1 Antibody (2J206)
Anti-BACE1 Antibody (2J206) is an antibody targeting BACE1. Anti-BACE1 Antibody (2J206) can be used in ELISA, WB.Forma y color:Odour LiquidAnti-BACE1 Antibody (8A762)
Anti-BACE1 Antibody (8A762) is a Rabbit antibody targeting BACE1. Anti-BACE1 Antibody (8A762) can be used in ELISA.Forma y color:Odour LiquidAnti-BACE1 Antibody (3R945)
Anti-BACE1 Antibody (3R945) is a Mouse antibody targeting BACE1. Anti-BACE1 Antibody (3R945) can be used in ELISA.Forma y color:Odour LiquidAnti-BACE1 Antibody (8D358)
Anti-BACE1 Antibody (8D358) is a Rabbit antibody targeting BACE1. Anti-BACE1 Antibody (8D358) can be used in FCM,ICC/IF.Forma y color:Odour LiquidBACE1 Protein, Human, Recombinant
BACE1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 49 kDa and the accession number is A0A024R3D7.Forma y color:Lyophilized PowderPeso molecular:49 kDa (predicted); 65 kDa (reducing condition, due to glycosylation)BACE1 Protein, Human, Recombinant (His)
BACE1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Forma y color:Lyophilized PowderPeso molecular:49.5 kDa (predicted); 55-70 kDa (reducing condition, due to glycosylation)Ref: TM-TMPY-00752
1mg3.046,00€5µg77,00€10µg110,00€20µg167,00€50µg334,00€100µg654,00€200µg909,00€500µg1.598,00€Sophoflavescenol
CAS:Sophoflavescenol: PDE5 inhibitor (K(i) 0.005 µM), antioxidant, anti-inflammatory, pro-apoptotic, potential antitumor, mild side effects.Fórmula:C21H20O6Pureza:99.65%Forma y color:SolidPeso molecular:368.38Aloeresin D
CAS:Aloeresin D, a natural chromone glycoside, inhibits β-Secretase (BACE1) activity (IC50: 39 μM).
Fórmula:C29H32O11Pureza:98.11% - 99.57%Forma y color:SolidPeso molecular:556.56Eslicarbazepine Acetate
CAS:Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use as an adjunctive therapy for partial-onset seizures.Fórmula:C17H16N2O3Pureza:99.58% - >99.99%Forma y color:White To Off-White SolidPeso molecular:296.32Ref: TM-T3285
5mg35,00€10mg52,00€25mg87,00€50mg117,00€100mg161,00€200mg254,00€500mg371,00€1mL*10mM (DMSO)52,00€LX2343
CAS:LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.Fórmula:C22H19ClN2O6SPureza:99.45%Forma y color:SolidPeso molecular:474.91Ref: TM-T4398
2mg34,00€5mg50,00€10mg79,00€25mg130,00€50mg216,00€100mg323,00€200mg447,00€1mL*10mM (DMSO)55,00€Scoulerine
CAS:Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1).Fórmula:C19H21NO4Pureza:98.62%Forma y color:SolidPeso molecular:327.37Aloenin
CAS:1. Aloenin (Aloenin A) and aloe-emodin are active principles for inhibition of c-ADH and c-ALDH activities in vitro.
Fórmula:C19H22O10Pureza:99.42% - 99.69%Forma y color:SolidPeso molecular:410.37Umibecestat HCl
CAS:Umibecestat HCl (CNP520 HCl) is an efficient β-secretase (BACE1/BACE2) inhibitor that reduces Aβ levels in mice and rats.Fórmula:C19H16Cl2F7N5O2Pureza:99.92%Forma y color:SolidPeso molecular:550.26Tenuifolin
CAS:Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.Fórmula:C36H56O12Pureza:97.37% - 99.54%Forma y color:SolidPeso molecular:680.82LY2886721
CAS:LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.Fórmula:C18H16F2N4O2SPureza:99% - 99.75%Forma y color:SolidPeso molecular:390.41
