AChR
Los inhibidores del receptor de acetilcolina (AChR) son compuestos que bloquean la actividad de los receptores de acetilcolina, que son críticos para la neurotransmisión en los sistemas nerviosos central y periférico. Los AChRs juegan un papel vital en la contracción muscular, la memoria y las funciones cognitivas. Los inhibidores de los AChRs se utilizan para estudiar afecciones como la miastenia gravis, la enfermedad de Alzheimer y otros trastornos neurológicos. Al modular la actividad de los AChRs, estos inhibidores pueden ayudar a desentrañar las complejidades de la señalización colinérgica en el cerebro. En CymitQuimica, ofrecemos una gama de inhibidores de AChR para apoyar su investigación en neurociencia, farmacología y enfermedades neurodegenerativas.
Se han encontrado 625 productos para "AChR".
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TAK-071
CAS:TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM).Fórmula:C24H24FN3O3Pureza:98.02% - 99.82%Forma y color:SolidPeso molecular:421.4641Temephos
CAS:Temephos is an organothiophosphate insecticide and cholinesterase inhibitor for treating water with disease-carrying insects.Fórmula:C16H20O6P2S3Pureza:≥95%Forma y color:Transparent OilPeso molecular:466.47Dicyclomine hydrochloride
CAS:Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence.Fórmula:C19H36ClNO2Pureza:99.81%Forma y color:SolidPeso molecular:345.948DL-trihexyphenidyl hydrochloride
CAS:DL-trihexyphenidyl hydrochloride (Trihexyphenidyl HCl) is a muscarinic antagonist.Fórmula:C20H32ClNOPureza:99.63% - 99.71%Forma y color:White SolidPeso molecular:337.93Diphenmanil methylsulfate
CAS:Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors.Fórmula:C21H27NO4SPureza:98% - 99.27%Forma y color:White SolidPeso molecular:389.508VU 0365114
CAS:VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).Fórmula:C22H14F3NO3Pureza:99.86%Forma y color:Red SolidPeso molecular:397.35Methscopolamine
CAS:Methscopolamine (Hyoscine methyl bromide) (Pamine), as a natural plant alkaloid, is a muscarinic acetylcholine receptor blocker.Fórmula:C18H24BrNO4Pureza:99.12% - ≥98%Forma y color:White SolidPeso molecular:398.291Promethazine hydrochloride
CAS:Promethazine HCl: First-gen antihistamine, H1 and mACh blocker, affects 5-HT2A/C, D2, α1 receptors.Fórmula:C17H20N2S·HClPureza:99.85%Forma y color:Crystals In Water Has A Ph Of 3 5-5 0 (Ntp 1992)Peso molecular:320.88Pirenzepine dihydrochloride
CAS:Pirenzepine dihydrochloride (LS519) is a selective M1 muscarinic receptor antagonist, inhibiting gastric secretion.Fórmula:C19H21N5O2·2HClPureza:99.48% - 99.62%Forma y color:SolidPeso molecular:424.328-Aminoadenine
CAS:8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.Fórmula:C5H6N6Pureza:99.82%Forma y color:SolidPeso molecular:150.14Adiphenine hydrochloride
CAS:Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.Fórmula:C20H26ClNO2Pureza:97.76% - 99.53%Forma y color:White Or Almost White PowderPeso molecular:347.879Benzethonium chloride
CAS:Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.Fórmula:C27H42ClNO2Pureza:99.91%Forma y color:White SolidPeso molecular:448.081MK-7622
CAS:MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.Fórmula:C25H25N3O2Pureza:99.77% - 99.8%Forma y color:SolidPeso molecular:399.4849Pyrantel tartrate
CAS:Pyrantel tartrate (Banminth) is broad spectrum anthelmintic for livestock.Fórmula:C15H20N2O6SPureza:99.96%Forma y color:White CrystalsPeso molecular:356.394(Rac)-ABT-202 dihydrochloride
CAS:(Rac)-ABT-202 dihydrochloride is a racemate of ABT-202. ABT-202 is an nicotinic acetylcholine receptors (nAChRs) agonist and can be used as an analgesic.Fórmula:C9H15Cl2N3Pureza:98.72%Forma y color:SolidPeso molecular:236.142Bethanechol chloride
CAS:Bethanechol chloride: muscarinic agonist, boosts smooth muscle tone, used post-abdominal surgery & for urinary retention; may cause hypotension & bronchospasm.Fórmula:C7H17N2O2·ClPureza:95% - 99.98%Forma y color:White SolidPeso molecular:196.68Deschloroclozapine
CAS:Deschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist.Fórmula:C18H20N4Pureza:99.61% - 99.98%Forma y color:Yellow SolidPeso molecular:292.3782Acetamiprid
CAS:Acetamiprid: nAChR agonist, global neonicotinoid insecticide linked to neuromuscular/reproductive issues.Fórmula:C10H11ClN4Pureza:99.66% - 99.89%Forma y color:White PowderPeso molecular:222.674Carbachol
CAS:Carbachol (Carbamoylcholine chloride), an analog of acetylcholine, serves as a valuable tool in the investigation of various physiological responses mediated by nicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors. These responses include smooth muscle contraction, gut motility, and neuronal signaling. Known for its agonistic properties, Carbachol activates both nAChR and mAChR, with reported Ki values ranging from 10 to 10,000 nM for different receptor types and experimental preparations.Fórmula:C6H15ClN2O2Pureza:99.81% - >99.99%Forma y color:SolidPeso molecular:182.65Orphenadrine Citrate
CAS:Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.Fórmula:C24H31NO8Pureza:99.58%Forma y color:White SolidPeso molecular:461.5048
