PAI-1
El Plasminogen Activator Inhibitor-1 (PAI-1) es un inhibidor de la serina proteasa que regula la fibrinólisis al inhibir el activador del plasminógeno tisular (tPA) y la uroquinasa (uPA). Niveles elevados de PAI-1 están asociados con un mayor riesgo de trombosis, enfermedades cardiovasculares y síndrome metabólico. Los inhibidores de PAI-1 están siendo investigados por su potencial en el tratamiento de estas condiciones. En CymitQuimica, ofrecemos inhibidores de PAI-1 para apoyar su investigación en hematología, salud cardiovascular y enfermedades metabólicas.
Se han encontrado 26 productos de "PAI-1"
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Upamostat
CAS:Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.Fórmula:C32H47N5O6SPureza:99.41%Forma y color:SolidPeso molecular:629.81Ref: TM-T13257
1mg64,00€2mg94,00€5mg145,00€10mg226,00€25mg379,00€50mg538,00€100mg730,00€1mL*10mM (DMSO)163,00€Angstrom6
CAS:Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascadeFórmula:C39H62N10O15Pureza:99.36%Forma y color:SolidPeso molecular:910.97CT140
CT140 is a human IgG4 monoclonal antibody (mAb) that specifically targets PAI-1. The suggested isotype control for this compound is Human IgG4 kappa, Isotype Control.Forma y color:Odour LiquidGGACK hydrochloride
<p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Fórmula:C14H26Cl2N6O5Forma y color:SolidPeso molecular:428.13417Nattokinase
CAS:Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.Forma y color:SolidUK140
UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.Fórmula:C72H105N19O25S3Forma y color:SolidPeso molecular:1732.91Bicyclic UK18
CAS:Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.Fórmula:C77H118N26O25S3Forma y color:SolidPeso molecular:1904.116-Aminocaproic acid (Standard)
CAS:6-Aminocaproic acid (Standard) is the standard substance of 6-Aminocaproic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 6-Aminocaproic acid (EACA) is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Fórmula:C6H13NO2Forma y color:Fine White Crystalline Powder SolidPeso molecular:131.17TM5441
CAS:TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.Fórmula:C21H17ClN2O6Pureza:97.62% - 99.09%Forma y color:SolidPeso molecular:428.82Tiplaxtinin
CAS:<p>Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.</p>Fórmula:C24H16F3NO4Pureza:99.16% - 99.93%Forma y color:SolidPeso molecular:439.38UK-371804
CAS:UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.Fórmula:C14H16ClN5O4SPureza:95.81% - 99.77%Forma y color:SolidPeso molecular:385.83Ref: TM-T3442
1mg52,00€2mg66,00€5mg108,00€10mg180,00€25mg324,00€50mg487,00€100mg705,00€500mg1.473,00€1mL*10mM (DMSO)117,00€Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Fórmula:C18H20O5Pureza:99.33% - 99.86%Forma y color:SolidPeso molecular:316.35TM5007
CAS:TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).Fórmula:C24H20N2O6S4Pureza:96.91%Forma y color:SolidPeso molecular:560.69TM5275 sodium
CAS:TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).Fórmula:C28H27ClN3NaO5Pureza:98.8% - 99.74%Forma y color:SolidPeso molecular:543.98Ref: TM-T4255
2mg42,00€5mg65,00€10mg87,00€25mg169,00€50mg245,00€100mg353,00€200mg492,00€1mL*10mM (DMSO)71,00€Toddalolactone
CAS:Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.Fórmula:C16H20O6Pureza:99.8% - 99.85%Forma y color:SolidPeso molecular:308.33Ref: TM-T4S0592
2mg37,00€5mg52,00€10mg73,00€25mg105,00€50mg152,00€100mg215,00€200mg320,00€1mL*10mM (DMSO)63,00€MDI-2268
CAS:MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.Fórmula:C10H10F3N3O3Forma y color:SolidPeso molecular:277.20Diaplasinin
CAS:Diaplasinin (PAI-749) is a potent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with antithrombotic activity, used in cardiovascular disease research.Fórmula:C32H31N5OPureza:99.02%Forma y color:SolidPeso molecular:501.62Ref: TM-T25915
1mg60,00€5mg127,00€10mg188,00€25mg432,00€50mg747,00€100mg1.216,00€1mL*10mM (DMSO)140,00€UK-371804 HCl
CAS:UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-Fórmula:C14H17Cl2N5O4SPureza:98%Forma y color:SolidPeso molecular:422.29SK-216
CAS:SK-216,PAI-1 inhibitor. Reduces tumor angiogenesis. Inhibits VEGF-induced endothelial cell migration. Alleviates pulmonary fibrosis.Fórmula:C29H29NNa2O6Pureza:98.29%Forma y color:SolidPeso molecular:533.52p-Aminobenzamidine dihydrochloride
CAS:4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase typeFórmula:C7H11Cl2N3Pureza:99.00% - 99.56%Forma y color:SolidPeso molecular:208.088
