Células madre y Derivados
Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.
Subcategorías de "Células madre y Derivados"
- Gamma-secretasa(59 productos)
- Hedgehog / Smoothened(44 productos)
- Hippo pathway(6 productos)
- JAK(245 productos)
- Porcupine (Puerco espín)(9 productos)
- ROCK(70 productos)
- STAT(98 productos)
- Células madre(486 productos)
- TGF-beta / Smad(58 productos)
- Wnt / beta-catenina(66 productos)
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Se han encontrado 695 productos de "Células madre y Derivados"
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TTP 22
CAS:<p>TTP 22: ATP-competitive CK2 inhibitor; IC50/Ki: 0.1 μM/40 nM; >250x selective over JNK3, ROCK1, MET.</p>Fórmula:C16H14N2O2S2Pureza:97.08% - 97.78%Forma y color:SolidPeso molecular:330.42SH-4-54
CAS:<p>SH-4-54 is a most potent, small molecule, nonphosphorylated STAT3 inhibitor.</p>Fórmula:C29H27F5N2O5SPureza:98% - 99.12%Forma y color:SolidPeso molecular:610.59TDZD-8
CAS:<p>TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.</p>Fórmula:C10H10N2O2SPureza:97.13% - 99.61%Forma y color:White SolidPeso molecular:222.26JI130
CAS:<p>JI130 hinders Hes1 transcription repression; notably shrinks pancreatic tumor volume in mice.</p>Fórmula:C23H24N2O3Pureza:99.61%Forma y color:SolidPeso molecular:376.45GS87
CAS:<p>GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.</p>Fórmula:C16H11N5O2SPureza:98.86%Forma y color:SolidPeso molecular:337.36Tegatrabetan
CAS:<p>Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.</p>Fórmula:C28H36N4O6S2Pureza:98.01% - 99.18%Forma y color:SolidPeso molecular:588.74Baricitinib
CAS:<p>Baricitinib (INCB028050) is an orally JAK1 and JAK2 inhibitor. Baricitinib has anti-inflammatory and anti-tumor activity. Cost-effective and quality-assured.</p>Fórmula:C16H17N7O2SPureza:99% - >99.99%Forma y color:SolidPeso molecular:371.42Hydroxyfasudil
CAS:<p>Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).</p>Fórmula:C14H17N3O3SPureza:98.13%Forma y color:SolidPeso molecular:307.37Porcn-IN-1
CAS:<p>Porcn-IN-1 (Porcupine-IN-1) is an effective porcupine inhibitor (IC50: 0.5±0.2 nM).</p>Fórmula:C25H19FN4OPureza:99.15%Forma y color:SolidPeso molecular:410.44Thiazovivin
CAS:<p>Thiazovivin, a ROCK inhibitor (IC50: 0.5 μM), increases the survival rate of hESC.</p>Fórmula:C15H13N5OSPureza:98.00%Forma y color:SolidPeso molecular:311.36GDC-0214
CAS:<p>GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).</p>Fórmula:C28H28ClF2N9O3Pureza:99.75%Forma y color:SolidPeso molecular:612.03IWP-O1
CAS:<p>IWP-O1 is a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.</p>Fórmula:C26H20N6OPureza:99.12%Forma y color:SolidPeso molecular:432.482,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:<p>2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.</p>Fórmula:C16H13Cl2N3O2Pureza:98.77%Forma y color:SolidPeso molecular:350.2(E/Z)-GO289
CAS:<p>(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2.</p>Fórmula:C17H15BrN4O2SPureza:98.1%Forma y color:SolidPeso molecular:419.3BIO-013077-01
CAS:<p>BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.</p>Fórmula:C17H13N5Pureza:99.87%Forma y color:SolidPeso molecular:287.32AS-252424
CAS:<p>AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.</p>Fórmula:C14H8FNO4SPureza:99.06% - 99.09%Forma y color:SolidPeso molecular:305.28Filgotinib
CAS:<p>Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.</p>Fórmula:C21H23N5O3SPureza:98.03% - ≥95%Forma y color:SolidPeso molecular:425.5Upadacitinib
CAS:<p>Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.</p>Fórmula:C17H19F3N6OPureza:98.96% - 99.94%Forma y color:SolidPeso molecular:380.37KenPaullone
CAS:<p>KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation.</p>Fórmula:C16H11BrN2OPureza:97.14% - 98.99%Forma y color:Tan SolidPeso molecular:327.18Crenigacestat
CAS:<p>Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most of the tumor cell lines tested.</p>Fórmula:C22H23F3N4O4Pureza:97.27% - 98.99%Forma y color:SolidPeso molecular:464.44
