Células madre y Derivados

Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.

Subcategorías de "Células madre y Derivados"

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Se han encontrado 695 productos de "Células madre y Derivados"

Pureza (%)

100

productos por página.

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Pacritinib hydrochloride
CAS:
- 1228923-43-0
Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.
Fórmula:C₂₈H₃₂N₄O₃·xClH
Forma y color:Solid
Ref: TM-T64283
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(E)-SIS3
CAS:
- 521984-48-5
(E)-SIS3 (SIS3) is a Smad3 inhibitor (IC50=3 μM) selective.inhibits the differentiation of fibroblasts into myofibroblasts via TGF-β1. High-Quality, Low-Cost!
Fórmula:C₂₈H₂₇N₃O₃·HCl
Pureza:95.64% - 98%
Forma y color:Solid
Peso molecular:489.99
Ref: TM-T3636
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AZD2858
CAS:
- 486424-20-8
AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway.
Fórmula:C₂₁H₂₃N₇O₃S
Pureza:98% - 99.25%
Forma y color:Solid
Peso molecular:453.52
Ref: TM-T1957
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Wnt-C59
CAS:
- 1243243-89-1
Wnt-C59 (C59)(C59) is a highly effective and specific Wnt signaling antagonis with PORCN enzymatic activity.
Fórmula:C₂₅H₂₁N₃O
Pureza:99.56% - 99.95%
Forma y color:Solid
Peso molecular:379.45
Ref: TM-T2242
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SAR407899
CAS:
- 923359-38-0
SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.
Fórmula:C₁₄H₁₆N₂O₂
Pureza:99.42%
Forma y color:Solid
Peso molecular:244.29
Ref: TM-T7391
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SRI-011381 hydrochloride
CAS:
- 2070014-88-7
SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
Fórmula:C₂₀H₃₂ClN₃O
Pureza:99.32% - 99.41%
Forma y color:Solid
Peso molecular:365.94
Ref: TM-T5129
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FLLL32
CAS:
- 1226895-15-3
FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).
Fórmula:C₂₈H₃₂O₆
Pureza:97% - 97.90%
Forma y color:Solid
Peso molecular:464.55
Ref: TM-T6838
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Gusacitinib HCl
CAS:
- 2228989-14-6
Gusacitinib (ASN-002/EN-3351), a potent SYK/JAK inhibitor, has strong antitumor activity in various cancers.
Fórmula:C₂₄H₂₉ClN₈O₂
Forma y color:Solid
Peso molecular:497
Ref: TM-T69766
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SR-3029
CAS:
- 1454585-06-8
SR-3029 is a potent and highly specific CK1δ/CK1ε inhibitor.
Fórmula:C₂₃H₁₉F₃N₈O
Pureza:99.64%
Forma y color:Solid
Peso molecular:480.45
Ref: TM-T3972
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MRT-14
CAS:
- 1263131-83-4
MRT-14 is a potent Smo antagonist and can be used in several types of cancers linked to abnormal Hh signaling studies.
Fórmula:C₂₄H₂₄N₄O₅
Pureza:99.54%
Forma y color:Solid
Peso molecular:448.47
Ref: TM-T9531
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RO495
CAS:
- 1258296-60-4
RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assays
Fórmula:C₁₇H₁₄Cl₂N₆O
Pureza:97.94%
Forma y color:Solid
Peso molecular:389.24
Ref: TM-T22416
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(E/Z)-Zotiraciclib
CAS:
- 937270-47-8
(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.
Fórmula:C₂₃H₂₄N₄O
Pureza:97.75% - 99.92%
Forma y color:Solid
Peso molecular:372.46
Ref: TM-T21503
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ROCK-IN-2
CAS:
- 867017-68-3
ROCK-IN-2 (Azaindole 1) is a selective and ATP-competitive ROCK inhibitor with IC50 of 0.6 and 1.1 nM for human ROCK-1 and ROCK-2.
Fórmula:C₁₈H₁₃ClF₂N₆O
Pureza:97.29%
Forma y color:Solid
Peso molecular:402.79
Ref: TM-TQ0110
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Fz7-21
CAS:
- 2247635-23-8
Fz7-21, a peptide antagonist of FZD7, inhibits Wnt/β-catenin signaling (IC50=50-100nM) in cells with WNT3A.
Fórmula:C₈₃H₁₁₄N₁₈O₂₃S₂
Pureza:99.8%
Forma y color:Solid
Peso molecular:1796.03
Ref: TM-TP1263
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G5-7
CAS:
- 939681-36-4
G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.
Fórmula:C₂₂H₁₉F₂NO₃
Pureza:97.3%
Forma y color:Solid
Peso molecular:383.39
Ref: TM-T8742
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Decernotinib
CAS:
- 944842-54-0
Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.
Fórmula:C₁₈H₁₉F₃N₆O
Pureza:99.28% - >99.99%
Forma y color:Solid
Peso molecular:392.38
Ref: TM-T2636
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γ-secretase modulator 1 hydrochloride
CAS:
- 2741571-83-3
gamma-secretase inhibitior-1 is a gamma-secretase modulator that is useful to Alzheimer's disease [1].
Fórmula:C₂₄H₂₅ClN₄OS
Pureza:98%
Forma y color:Solid
Peso molecular:453
Ref: TM-T11358L
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Gandotinib
CAS:
- 1229236-86-5
LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).
Fórmula:C₂₃H₂₅ClFN₇O
Pureza:99.33% - 99.86%
Forma y color:Solid
Peso molecular:469.94
Ref: TM-T2638
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Wnt pathway activator 1
CAS:
- 1360540-81-3
Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM.
Fórmula:C₁₈H₁₆O₄
Pureza:99.93%
Forma y color:Solid
Peso molecular:296.32
Ref: TM-T17256
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AMG-47a
CAS:
- 882663-88-9
AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.
Fórmula:C₂₉H₂₈F₃N₅O₂
Pureza:98%
Forma y color:Solid
Peso molecular:535.56
Ref: TM-T7123