Células madre y Derivados

Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.

Subcategorías de "Células madre y Derivados"

Mostrar 2 subcategorías más

Se han encontrado 689 productos de "Células madre y Derivados"

Pureza (%)

100

productos por página.

+ Info
Solcitinib
CAS:
- 1206163-45-2
Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.
Fórmula:C₂₂H₂₃N₅O₂
Pureza:99.61% - 99.82%
Forma y color:Solid
Peso molecular:389.45
Ref: TM-T3620
+ Info
RO8191
CAS:
- 691868-88-9
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
Fórmula:C₁₄H₅F₆N₅O
Pureza:98% - 98.85%
Forma y color:Solid
Peso molecular:373.21
Ref: TM-T22142
+ Info
IWR-1
CAS:
- 1127442-82-3
IWR-1 (IWR-1-endo), a Wnt pathway inhibitor, stabilizes the Axin destruction complex(EC50=0.2 uM).
Fórmula:C₂₅H₁₉N₃O₃
Pureza:99.19% - 99.82%
Forma y color:Solid
Peso molecular:409.44
Ref: TM-T2651
+ Info
TED-347
CAS:
- 2378626-29-8
TED-347 is an irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.
Fórmula:C₁₅H₁₁ClF₃NO
Pureza:99.9%
Forma y color:Solid
Peso molecular:313.7
Ref: TM-T8421
+ Info
SD-208
CAS:
- 627536-09-8
SD-208 (ALK5 Inhibitor V), a selective TGF-βRI (ALK5) inhibitor (IC50: 48 nM), is >100-fold selectivity over TGF-βRII.
Fórmula:C₁₇H₁₀ClFN₆
Pureza:98.72% - 99.65%
Forma y color:Solid
Peso molecular:352.75
Ref: TM-T2109
+ Info
Fz7-21
CAS:
- 2247635-23-8
Fz7-21, a peptide antagonist of FZD7, inhibits Wnt/β-catenin signaling (IC50=50-100nM) in cells with WNT3A.
Fórmula:C₈₃H₁₁₄N₁₈O₂₃S₂
Pureza:99.8%
Forma y color:Solid
Peso molecular:1796.03
Ref: TM-TP1263
+ Info
PF-4800567
CAS:
- 1188296-52-7
PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ.
Fórmula:C₁₇H₁₈ClN₅O₂
Pureza:99.76%
Forma y color:Solid
Peso molecular:359.81
Ref: TM-T5056
+ Info
IWP L6
CAS:
- 1427782-89-5
IWP L6 (Porcn Inhibitor III) is an extremely effective Porcn inhibitor (EC50: 0.5 nM).
Fórmula:C₂₅H₂₀N₄O₂S₂
Pureza:99.51% - >99.99%
Forma y color:Solid
Peso molecular:472.58
Ref: TM-T2683
+ Info
Avagacestat
CAS:
- 1146699-66-2
Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM,
Fórmula:C₂₀H₁₇ClF₄N₄O₄S
Pureza:98.87% - 99.73%
Forma y color:Solid
Peso molecular:520.89
Ref: TM-T6249
+ Info
KY02111
CAS:
- 1118807-13-8
KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.
Fórmula:C₁₈H₁₇ClN₂O₃S
Pureza:97.71% - 98.3%
Forma y color:Solid
Peso molecular:376.86
Ref: TM-T2052
+ Info
MRT-14
CAS:
- 1263131-83-4
MRT-14 is a potent Smo antagonist and can be used in several types of cancers linked to abnormal Hh signaling studies.
Fórmula:C₂₄H₂₄N₄O₅
Pureza:99.54%
Forma y color:Solid
Peso molecular:448.47
Ref: TM-T9531
+ Info
RO495
CAS:
- 1258296-60-4
RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assays
Fórmula:C₁₇H₁₄Cl₂N₆O
Pureza:97.94%
Forma y color:Solid
Peso molecular:389.24
Ref: TM-T22416
+ Info
Filgotinib
CAS:
- 1206161-97-8
Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.
Fórmula:C₂₁H₂₃N₅O₃S
Pureza:98.03% - ≥95%
Forma y color:Solid
Peso molecular:425.5
Ref: TM-T1929
+ Info
Cardiogenol C
CAS:
- 671225-39-1
Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.
Fórmula:C₁₃H₁₆N₄O₂
Pureza:98.46%
Forma y color:Solid
Peso molecular:260.29
Ref: TM-T2161
+ Info
IQ 1
CAS:
- 331001-62-8
IQ 1 has multiple roles, such as maintaining the multifunctionality of mouse ESCs, decreasing Wnt-stimulated phosphorylation, blocking PP2A/Nkd interactions.
Fórmula:C₂₁H₂₂N₄O₂
Pureza:98.57% - ≥95%
Forma y color:Solid
Peso molecular:362.42
Ref: TM-T3635
+ Info
SR-3677
CAS:
- 1072959-67-1
SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).
Fórmula:C₂₂H₂₄N₄O₄
Pureza:98.46%
Forma y color:Solid
Peso molecular:408.45
Ref: TM-TQ0187
+ Info
BDP5290
CAS:
- 1817698-21-7
BDP5290 is a potent inhibitor of both ROCK and MRCK(IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.)
Fórmula:C₁₇H₁₈ClN₇O
Pureza:97.22%
Forma y color:Solid
Peso molecular:371.82
Ref: TM-T7301
+ Info
SAR-20347
CAS:
- 1450881-55-6
SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).
Fórmula:C₂₁H₁₈ClFN₄O₄
Pureza:98.99% - 99.77%
Forma y color:Solid
Peso molecular:444.84
Ref: TM-T4210
+ Info
LY3200882
CAS:
- 1898283-02-7
LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI).
Fórmula:C₂₄H₂₉N₅O₃
Pureza:99.46% - 99.63%
Forma y color:Solid
Peso molecular:435.52
Ref: TM-T5125
+ Info
JAK-IN-5 hydrochloride
CAS:
- 2751323-21-2
JAK-IN-5 hydrochloride is a JAK inhibitor [1].
Fórmula:C₂₇H₃₂ClFN₆O
Forma y color:Solid
Peso molecular:511.03
Ref: TM-T11710L