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Células madre y Derivados

Células madre y Derivados

Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.

Subcategorías de "Células madre y Derivados"

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Se han encontrado 693 productos de "Células madre y Derivados"

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  • CJJ300

    CAS:
    <p>CJJ300 is a TGF-β inhibitor disrupting TGF-β-TβR complex formation, with an IC50 of 5.3 μM, and halts cell migration.</p>
    Fórmula:C30H33N3
    Pureza:99.80%
    Forma y color:Solid
    Peso molecular:435.6
  • EP009

    CAS:
    <p>EP009, a novel, selective, and orally active inhibitor of JAK3, induces therapeutic response in T-cell malignancies.</p>
    Fórmula:C14H24O2
    Forma y color:Solid
    Peso molecular:224.34
  • OICR-0547

    CAS:
    <p>OICR-0547 is an inactive derivative of OICR-9429 and is commonly used as a negative control for OICR-9429.</p>
    Fórmula:C28H29F3N4O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:542.55
  • CK2α-IN-1

    CAS:
    <p>CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and can</p>
    Fórmula:C16H11N3O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:341.34
  • CK2-IN-4

    CAS:
    <p>CK2-IN-4 is a protein kinase (CK2) inhibitor with an IC50 value of 8.6 µM.</p>
    Fórmula:C18H11N3O4S
    Pureza:99.72%
    Forma y color:Solid
    Peso molecular:365.36
  • JAK3/BTK-IN-1

    CAS:
    <p>JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important</p>
    Fórmula:C25H28N8O
    Pureza:97.89%
    Forma y color:Solid
    Peso molecular:456.54
  • inS3-54-A26

    CAS:
    <p>inS3-54-A26 is an inhibitor of the DNA-binding domain of STAT3. inS3-54-A26 suppresses tumor growth, metastasis and the gene expression of STAT3.</p>
    Fórmula:C25H19ClN2O2
    Pureza:99.57%
    Forma y color:Solid
    Peso molecular:414.88
  • JAK-IN-14

    CAS:
    <p>JAK-IN-14 (compound 16) is a specific JAK1 inhibitor. It prevents JAK1 phosphorylation by binding to the active site of JAK in immune, inflammation and cancer.</p>
    Fórmula:C19H15FN4O
    Pureza:98.27%
    Forma y color:Solid
    Peso molecular:334.35
  • Tyk2-IN-5

    CAS:
    <p>Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).</p>
    Fórmula:C21H19FN8O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:434.43
  • H-1152

    CAS:
    <p>H-1152 is a potent, specific, ATP-competitive, and cell permeable ROCK inhibitor (Ki = 1.6 nM).</p>
    Fórmula:C16H21N3O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:319.42
  • TEAD-IN-2

    CAS:
    <p>TEAD-IN-2 is a potent and bifunctional TEAD inhibitor to induce TEAD protein degradation via the ubiquitination pathway, with anticancer potential.</p>
    Fórmula:C16H18BrF3N2O
    Forma y color:Solid
    Peso molecular:391.23
  • CAY10746

    CAS:
    <p>CAY10746 selectively inhibits ROCK I/II with IC50s: 0.014/0.003 μM, useful for diabetic retinopathy research.</p>
    Fórmula:C26H23N3O5
    Pureza:99.04%
    Forma y color:Solid
    Peso molecular:457.48
  • ELN318463

    CAS:
    <p>ELN 318463 selectively inhibits γ-secretase; EC50: 12 nM (PS1), 656 nM (PS2); 51x more selective for PS1; targets APP.</p>
    Fórmula:C19H20BrClN2O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:471.8
  • JAK3-IN-12

    CAS:
    <p>JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.</p>
    Fórmula:C19H19N5O4S
    Forma y color:Solid
    Peso molecular:413.45
  • GSK-3β inhibitor 12

    CAS:
    <p>GSK-3β inhibitor 12 is a selective GSK-3β inhibitor.GSK-3β inhibitor 12 inhibits 49.11% of 25 μM GSK-3β activity and 37.11% of 50 μM GSK-3β activity.GSK-3β</p>
    Fórmula:C14H13N3OS
    Pureza:98.58%
    Forma y color:Solid
    Peso molecular:271.34
  • SR-1277

    CAS:
    <p>SR-1277 is a potent, highly selective and ATP-competitive CK1δ/ε inhibitor, regulating Wee1 activity at the G2/M cell-cycle interface, and antiproliferative.</p>
    Fórmula:C21H19N9O3S
    Forma y color:Solid
    Peso molecular:477.5
  • JAK-IN-11

    CAS:
    <p>JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.</p>
    Fórmula:C23H22FN5O4S
    Pureza:99.75%
    Forma y color:Solid
    Peso molecular:483.52
  • LY-411575 isomer 1

    CAS:
    <p>LY-411575 isomer 1 is a potent γ-secretase inhibitor. LY-411575 isomer 1 is an isomer of LY411575.</p>
    Fórmula:C26H23F2N3O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:479.48
  • AF-2112


    <p>AF-2112, a TEAD inhibitor derived from Flufenamic acid, significantly diminishes the expression of CTGF, Cyr61, Axl, and NF2.</p>
    Fórmula:C21H18FNO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:351.37
  • TEAD-IN-6

    CAS:
    <p>TEAD-IN-6 (Example 11-1) is a TEAD modulator that inhibits the YAP1/TAZ-TEAD interaction, and has applications in cancer research [1].</p>
    Fórmula:C19H17F3N4O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:438.42