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Células madre y Derivados

Células madre y Derivados

Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.

Subcategorías de "Células madre y Derivados"

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Se han encontrado 693 productos de "Células madre y Derivados"

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  • JAK-IN-18
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    JAK-IN-18

    CAS:
    <p>"JAK-IN-18: potent JAK inhibitor for eye, skin, respiratory disease research (WO2018204238A1, comp 1)."</p>
    Fórmula:C27H28F2N6O3
    Forma y color:Solid
    Peso molecular:522.55

    Ref: TM-T63658

  • JAK-IN-28
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    JAK-IN-28

    CAS:
    <p>JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].</p>
    Fórmula:C20H18ClN7O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:407.86

    Ref: TM-T79116

  • JAK-IN-30
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    JAK-IN-30

    CAS:
    <p>JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50</p>
    Fórmula:C19H26N8S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:398.53

    Ref: TM-T79235

  • PIMPC
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    PIMPC

    CAS:
    <p>PIMPC, a compound endowed with antioxidant and metal-chelating properties, acts as a novel inhibitor of glycogen synthase kinase 3 (GSK-3), and exhibits</p>
    Fórmula:C21H19N5O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:357.41

    Ref: TM-T79693

  • Aβ42-IN-2
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    Aβ42-IN-2

    CAS:
    <p>Aβ42-IN-2 is a γ-secretase modulator. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ 42. Aβ42-IN-2 can be used for the Alzheimer's disease research[1].</p>
    Fórmula:C24H26N6O2
    Pureza:98.09% - 99.87%
    Forma y color:Solid
    Peso molecular:430.5

    Ref: TM-T9641

  • γ-secretase modulator 2
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    γ-secretase modulator 2

    CAS:
    <p>Gamma-secretase modulator 2 selectively targets Alzheimer's by reducing Aβ(1-42), aiding in prevention and treatment.</p>
    Fórmula:C25H22F4N6O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:514.47

    Ref: TM-T11359

  • tCFA15
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    tCFA15

    CAS:
    <p>tCFA15: A trimethylated long-chain fatty alcohol with a 15-carbon side chain; may regulate Notch signaling and neuron differentiation.</p>
    Fórmula:C24H44O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:364.61

    Ref: TM-T13917

  • Chromenone 1
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    Chromenone 1

    CAS:
    <p>Chromenone 1 is a potent potentiator of osteogenic bone morphogenetic protein (BMP).</p>
    Fórmula:C18H10F3N3O2
    Pureza:99.83% - 99.93%
    Forma y color:Solid
    Peso molecular:357.29

    Ref: TM-T61301

  • γ-Secretase modulator 4
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    γ-Secretase modulator 4

    CAS:
    <p>γ-Secretase modulator 4 is a potent γ-secretase modulator, reduces the Aβ42 level with IC50s of 0.017 μM and 0.014 μM in mouse and human, respectively.</p>
    Fórmula:C23H19FN4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:402.42

    Ref: TM-T11361

  • TK4g
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    TK4g

    CAS:
    <p>TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) &amp; 15.80 nM (JAK3); promising for lymphoid diseases &amp; leukemia research.</p>
    Fórmula:C19H19N3O4S
    Forma y color:Solid
    Peso molecular:385.44

    Ref: TM-T61698

  • JAK1-IN-4
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    JAK1-IN-4

    CAS:
    <p>JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).</p>
    Fórmula:C26H32FN9O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:521.59

    Ref: TM-T15606

  • TyK2-IN-2
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    TyK2-IN-2

    CAS:
    <p>TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).</p>
    Fórmula:C16H18N6O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:310.35

    Ref: TM-T13232

  • GSK3-IN-2
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    GSK3-IN-2

    CAS:
    <p>GSK3-IN-2 is a potent GSK3 inhibitor for the treatment of diabetes and neurodegenerative diseases.</p>
    Fórmula:C17H19N3OS
    Pureza:98.8%
    Forma y color:Solid
    Peso molecular:313.42

    Ref: TM-T73270

  • JAK3/BTK-IN-2
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    JAK3/BTK-IN-2

    CAS:
    <p>JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.</p>
    Fórmula:C25H32N8O2
    Pureza:99.64% - 99.87%
    Forma y color:Solid
    Peso molecular:476.57

    Ref: TM-T9813

  • Aloisine B
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    Aloisine B

    CAS:
    <p>Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 µM and 0.75 µM, respectively.</p>
    Fórmula:C15H14ClN3
    Pureza:95.15%
    Forma y color:Solid
    Peso molecular:271.74

    Ref: TM-T69188

  • VT103
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    VT103

    CAS:
    <p>VT103, an oral TEAD1 palmitoylation inhibitor, shows promise against various cancers by disrupting YAP/TAZ-TEAD interactions.</p>
    Fórmula:C18H17F3N4O2S
    Pureza:99.58%
    Forma y color:Solid
    Peso molecular:410.41

    Ref: TM-T62077

  • Lorpucitinib
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    Lorpucitinib

    CAS:
    <p>Lorpucitinib (JNJ-64251330) is a JAK kinase inhibitor used in the study of inflammatory and gastrointestinal diseases.</p>
    Fórmula:C22H28N6O2
    Pureza:99.72%
    Forma y color:Solid
    Peso molecular:408.5

    Ref: TM-T62053

  • (2R,5S)-Ritlecitinib
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    (2R,5S)-Ritlecitinib

    CAS:
    <p>(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective inhibitor of JAK3 with IC 50 of 144.8 nM[1].</p>
    Fórmula:C15H19N5O
    Forma y color:Solid
    Peso molecular:285.34

    Ref: TM-T60565

  • Povorcitinib
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    Povorcitinib

    CAS:
    <p>Povorcitinib is a highly potent and selective JAK1 inhibitor with significant potential for the investigation of cutaneous lupus erythematosus (CLE) and Lichen planus (LP).</p>
    Fórmula:C23H22F5N7O
    Forma y color:Solid
    Peso molecular:507.469

    Ref: TM-T39113

  • TYK2-IN-11
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    TYK2-IN-11

    CAS:
    <p>TYK2-IN-11 (5B) selectively inhibits TYK2 (IC50: 0.016 nM) and JAK1 (IC50: 0.31 nM), aiding autoimmune and inflammatory disease research.</p>
    Fórmula:C18H17N5O3S
    Forma y color:Solid
    Peso molecular:383.42

    Ref: TM-T61658