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Células madre y Derivados

Células madre y Derivados

Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.

Subcategorías de "Células madre y Derivados"

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Se han encontrado 693 productos de "Células madre y Derivados"

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  • GDC-4379
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    GDC-4379

    CAS:
    <p>GDC-4379 is a JAK1 inhibitor that can be used to study asthma.</p>
    Fórmula:C21H18ClF2N7O3
    Forma y color:Solid
    Peso molecular:489.86

    Ref: TM-T63280

  • CP-690550A
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    CP-690550A

    CAS:
    <p>Cp-690550a is a novel JAK3 inhibitor, which is used to treat rheumatoid arthritis, graft rejection, psoriasis, and other immune-mediated diseases.</p>
    Fórmula:C15H21N5O2
    Forma y color:Solid
    Peso molecular:303.36

    Ref: TM-T31074

  • Yhhu-3792
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    Yhhu-3792

    CAS:
    <p>Yhhu-3792 activates Notch, boosts Hes3/Hes5, enhances NSC renewal, expands NSC pool, and may improve memory.</p>
    Fórmula:C24H24N4O2
    Forma y color:Solid
    Peso molecular:400.47

    Ref: TM-T61930

  • Thi-DPPY
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    Thi-DPPY

    CAS:
    <p>Thi-DPPY: Potent JAK3/BTK inhibitor (IC50: 1.38/62.4 nM), anti-proliferative, anti-inflammatory, potential in IPF research.</p>
    Fórmula:C28H28ClN5O4S
    Forma y color:Solid
    Peso molecular:566.07

    Ref: TM-T64008

  • Peficitinib hydrobromide
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    Peficitinib hydrobromide

    CAS:
    <p>Peficitinib hydrobromide is used in the treatment of Psoriasis and Rheumatoid Arthritis.</p>
    Fórmula:C18H23BrN4O2
    Forma y color:Solid
    Peso molecular:407.312

    Ref: TM-T33905

  • PF-00956980
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    PF-00956980

    CAS:
    <p>PF-00956980: reversible JAK inhibitor, IC50: JAK1 (2.2μM), JAK2 (23.1μM), JAK3 (59.9μM), for lung/skin inflammation research.</p>
    Fórmula:C18H26N6O
    Forma y color:Solid
    Peso molecular:342.44

    Ref: TM-T71089

  • γ-Secretase modulator 11
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    γ-Secretase modulator 11

    CAS:
    <p>5-{8-[(3,4'-Difluoro[1,1'-biphenyl]-4-yl)methoxy]-2-methylimidazo[1,2-a]pyridin-3-yl}-N-methylpyridine-2-carboxamide (1o) exhibited high in vitro potency and</p>
    Fórmula:C28H22F2N4O2
    Forma y color:Solid
    Peso molecular:484.5

    Ref: TM-T63216

  • SYK/JAK-IN-1
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    SYK/JAK-IN-1

    CAS:
    <p>SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.</p>
    Fórmula:C24H26N8O3
    Forma y color:Solid
    Peso molecular:474.52

    Ref: TM-T63086

  • TUL01101
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    TUL01101

    CAS:
    <p>TUL01101, a selective oral JAK1 inhibitor (IC50: 3 nM), also targets JAK2, JAK3, TYK2; for rheumatoid arthritis research.</p>
    Fórmula:C22H25F2N5O2
    Forma y color:Solid
    Peso molecular:429.46

    Ref: TM-T73392

  • JAK3i
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    JAK3i

    CAS:
    <p>JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.</p>
    Fórmula:C18H15FN4O3
    Pureza:98.61% - 99.81%
    Forma y color:Solid
    Peso molecular:354.34

    Ref: TM-T27650

  • TK4b
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    TK4b

    CAS:
    <p>TK4b, a JAK inhibitor, targets leukemia/lymphoid diseases, with IC50s: 18.42 nM (JAK3) &amp; 19.40 nM (JAK2).</p>
    Fórmula:C21H22N2O2
    Forma y color:Solid
    Peso molecular:334.41

    Ref: TM-T61020

  • BRD0209
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    BRD0209

    CAS:
    <p>BRD0209 is a highly selective and potent GSK3 inhibitor.</p>
    Fórmula:C22H25N3O
    Pureza:99.92%
    Forma y color:Solid
    Peso molecular:347.45

    Ref: TM-T26894

  • JA310
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    JA310

    CAS:
    <p>JA310 is a highly selective inhibitor of the MST3 kinase, demonstrating significant cellular potency with an EC50 value of 106 nM [1].</p>
    Fórmula:C17H19N7O
    Forma y color:Solid
    Peso molecular:337.38

    Ref: TM-T86752

  • RR-11a
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    RR-11a

    CAS:
    <p>RR-11a is a synthetic enzyme Legumain inhibitor.</p>
    Fórmula:C24H28N6O10
    Pureza:98%
    Forma y color:Solid
    Peso molecular:560.51

    Ref: TM-T12769

  • BPN-15606
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    BPN-15606

    CAS:
    <p>BPN-15606, an oral γ-secretase modulator, reduces Aβ42/Aβ40 with IC50 of 7/17 nM; promising PK/PD, lowers Aβ in rodent CNS.</p>
    Fórmula:C23H23FN6O
    Forma y color:Solid
    Peso molecular:418.47

    Ref: TM-T10589L

  • Peficitinib hydrochloride
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    Peficitinib hydrochloride

    CAS:
    <p>Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).</p>
    Fórmula:C18H23ClN4O2
    Forma y color:Solid
    Peso molecular:362.86

    Ref: TM-T61365

  • JAK-2/3-IN-2
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    JAK-2/3-IN-2

    CAS:
    <p>JAK-2/3-IN-2 (Compound 3h) is a potent JAK2 &amp; JAK3 inhibitor with IC50s of 23.85 nM (JAK2) &amp; 18.9 nM (JAK3).</p>
    Fórmula:C19H19ClN2OS
    Forma y color:Solid
    Peso molecular:358.89

    Ref: TM-T61323

  • Aβ42-IN-1 free base
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    Aβ42-IN-1 free base

    CAS:
    <p>Aβ42-IN-1 free base (compound 1v), an orally active γ-secretase modulator with high brain exposure, effectively lowers Aβ42 levels, exhibiting an IC 50 of 0.091</p>
    Fórmula:C29H26N4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:462.54

    Ref: TM-T10443

  • JAK-IN-20
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    JAK-IN-20

    CAS:
    <p>JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.</p>
    Fórmula:C28H30FN7O2
    Forma y color:Solid
    Peso molecular:515.58

    Ref: TM-T63581

  • ELN318463 racemate
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    ELN318463 racemate

    CAS:
    <p>ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor.</p>
    Fórmula:C19H20BrClN2O3S
    Pureza:99.69%
    Forma y color:Solid
    Peso molecular:471.8

    Ref: TM-T11178L