Células madre y Derivados

Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.

Subcategorías de "Células madre y Derivados"

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Se han encontrado 694 productos de "Células madre y Derivados"

Pureza (%)

100

productos por página.

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TT-10
CAS:
- 2230640-94-3
TT-10 (TAZ-K) activates YAP-TEAD; useful in heart disease with cardiomyocyte loss research.
Fórmula:C₁₁H₁₀FN₃OS₂
Pureza:99.29%
Forma y color:Solid
Peso molecular:283.35
Ref: TM-T69760
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FzM1
CAS:
- 1680196-54-6
FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2)
Fórmula:C₂₁H₁₆N₂O₂S
Pureza:99.37% - 99.89%
Forma y color:Solid
Peso molecular:360.43
Ref: TM-T24076
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LM-41
CAS:
- 2996821-30-6
LM-41 is a TEAD binding agent with potential anticancer activity for the study of breast cancer.
Fórmula:C₁₉H₁₄FNO₂
Pureza:99.73%
Forma y color:Solid
Peso molecular:307.32
Ref: TM-T79427
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GSK-3β inhibitor 2
CAS:
- 1702428-31-6
GSK-3β inhibitor 2 (5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy-) is a BBB-crossing and selective inhibitor of GSK-3β (IC50
Fórmula:C₁₄H₁₄N₄O₃S
Pureza:99.08%
Forma y color:Solid
Peso molecular:318.35
Ref: TM-T11471
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CRT0066854 hydrochloride
CAS:
- 2250019-91-9
CRT0066854 HCl inhibits atypical PKCs; IC50: PKCι 132 nM, PKCζ 639 nM, ROCK-II 620 nM.
Fórmula:C₂₄H₂₇Cl₂N₅S
Pureza:99.63%
Forma y color:Solid
Peso molecular:488.48
Ref: TM-T10888
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DIF-3
CAS:
- 113411-17-9
DIF-3 activates GSK-3β, degrades cyclin D1/c-Myc, and inhibits Wnt/β-catenin in DLD-1 cells, curbing HeLa cell proliferation.
Fórmula:C₁₃H₁₇ClO₄
Pureza:99.57%
Forma y color:Solid
Peso molecular:272.72
Ref: TM-T60485
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Rhodblock 6
CAS:
- 886625-06-5
Rhodblock 6 is a Rho kinase inhibitor, blocking phosphorylated MRLC localization by targeting ROCK activity.
Fórmula:C₁₂H₁₃N₃O
Pureza:98.27%
Forma y color:Solid
Peso molecular:215.25
Ref: TM-T26078
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CID-5056270
CAS:
- 681173-76-2
CID-5056270 has anticancer activity and can inhibit lung cancer, anal cancer, bladder cancer, cervical cancer, vulvar cancer, penile cancer, Burkitt's lymphoma
Fórmula:C₁₇H₁₃N₃O₃S
Pureza:99.6%
Forma y color:Solid
Peso molecular:339.37
Ref: TM-T23888
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JAK1-IN-8
CAS:
- 1973485-18-5
JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).
Fórmula:C₂₂H₂₃FN₄O₃S
Pureza:98.4%
Forma y color:Solid
Peso molecular:442.51
Ref: TM-T35899
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EHT 1610
CAS:
- 1425945-60-3
EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively.
Fórmula:C₁₈H₁₄FN₅O₂S
Pureza:98.59%
Forma y color:Solid
Peso molecular:383.4
Ref: TM-T15204
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FzM1.8
CAS:
- 2204290-85-5
FzM1.8: allosteric FZD4 agonist, pEC50=6.4; boosts TCF/LEF, activates WNT/β-catenin with no WNT needed.
Fórmula:C₁₈H₁₄N₂O₄
Pureza:99.89%
Forma y color:Solid
Peso molecular:322.31
Ref: TM-T15363
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XL413 xHCl
CAS:
- 1169562-71-3
BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215
Fórmula:C₁₄H₁₂ClN₃O₂·xHCl
Pureza:99.37% - 99.67%
Forma y color:Solid
Peso molecular:326.18
Ref: TM-T71339
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PI-828
CAS:
- 942289-87-4
PI-828 (LY 294002), a PI3K inhibitor, researches PI3K function and aids stem cell differentiation into mesoderm.
Fórmula:C₁₉H₁₈N₂O₃
Pureza:99.95%
Forma y color:Solid
Peso molecular:322.36
Ref: TM-T16528
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Butyzamide
CAS:
- 1110767-45-7
Butyzamide: oral Mpl activator, non-peptide, antagonizes TPO receptors, boosts hMpl, Ba/F3 cells, and enhances platelets in mice.
Fórmula:C₂₉H₃₂Cl₂N₂O₅S
Pureza:99.51% - 99.83%
Forma y color:Soild
Peso molecular:591.55
Ref: TM-T67894
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LEQ506
CAS:
- 1204975-42-7
LEQ506 is a Smo inhibitor with IC50s of 2 nM and 4 nM for hSmo and mSmo, respectively.
Fórmula:C₂₅H₃₂N₆O
Pureza:99.76%
Forma y color:Solid
Peso molecular:432.56
Ref: TM-T11838
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BIP-135
CAS:
- 941575-71-9
BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor.
Fórmula:C₂₁H₁₃BrN₂O₃
Pureza:99.93%
Forma y color:Solid
Peso molecular:421.24
Ref: TM-T14613
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SJ000063181
CAS:
- 945189-68-4
SJ000063181 activates BMP signaling (EC50 ≤1μM), usable as probe in zebrafish embryos.
Fórmula:C₁₄H₁₄ClFN₂O₂
Pureza:99.94%
Forma y color:Solid
Peso molecular:296.72
Ref: TM-T60644
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GSK-3 Inhibitor XIII
CAS:
- 404828-14-4
GSK-3 InhibitorXIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.
Fórmula:C₁₈H₁₅N₅
Pureza:99.85% - 99.86%
Forma y color:Solid
Peso molecular:301.35
Ref: TM-T78578
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IHMT-MST1-58
CAS:
- 2414484-25-4
IHMT-MST1-58 is a STE20-like protein 1 kinase (MST1) inhibitor (IC50:23 nM) with high efficiency, selectivity and oral activity.
Fórmula:C₂₁H₂₂N₆O₃S
Pureza:98.31% - 99.92%
Forma y color:Solid
Peso molecular:438.5
Ref: TM-T62512
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JAK-IN-24
CAS:
- 2042629-43-4
JAK-IN-24: JAK inhibitor, IC50: 0.534 nM (4 μM ATP), 24 nM (1mM ATP), STAT5 phosphorylation IC50: 86.171 nM.
Fórmula:C₂₀H₂₅N₅O₂
Forma y color:Solid
Peso molecular:367.44
Ref: TM-T73330