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Células madre y Derivados

Células madre y Derivados

Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.

Subcategorías de "Células madre y Derivados"

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Se han encontrado 695 productos de "Células madre y Derivados"

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  • TCS 21311
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    TCS 21311

    CAS:
    <p>TCS 21311 (NIBR3049) selectively inhibits JAK3 (IC50: 8 nM) and PKCα/θ &amp; GSK3β; &gt;100x selective over JAK1, JAK2, TYK2.</p>
    Fórmula:C27H25F3N4O4
    Pureza:99.39% - ≥98%
    Forma y color:Solid
    Peso molecular:526.51

    Ref: TM-T17019

  • Lepzacitinib
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    Lepzacitinib

    CAS:
    <p>Lepzacitinib is a selective, inflammatory, small molecule JAK1/3(Janus kinase) inhibitor primarily used for the treatment of atopic dermatitis.</p>
    Fórmula:C18H21N5O3
    Pureza:99.85%
    Forma y color:Solid
    Peso molecular:355.39

    Ref: TM-T78207

  • ROCK2-IN-6 hydrochloride
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    ROCK2-IN-6 hydrochloride

    CAS:
    <p>ROCK2-IN-6 hydrochloride (Comp A)为一种选择性ROCK2抑制剂，适用于研究ROCK介导的疾病、自身免疫性病症与炎症。</p>
    Fórmula:C26H22ClF2N7O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:521.95

    Ref: TM-T78205

  • TGFβ-IN-5
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    TGFβ-IN-5

    CAS:
    <p>TGFβ-IN-5 (WAY-641966) is a potent TGFβ inhibitor with anti-prion activity for the study of fibroproliferative diseases associated with TGF-β signaling.</p>
    Fórmula:C20H16N4
    Pureza:99.29% - 99.5%
    Forma y color:Solid
    Peso molecular:312.37

    Ref: TM-T77786

  • ROCK-IN-8
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    ROCK-IN-8

    CAS:
    <p>ROCK-IN-8 (Example 4), a ROCK inhibitor, exhibits anti-inflammatory properties and is suitable for respiratory and gastro-intestinal disease research,</p>
    Fórmula:C30H25FN4O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:556.61

    Ref: TM-T79809

  • Nezulcitinib
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    Nezulcitinib

    CAS:
    <p>Nezulcitinib (TD-0903) is an inhaled pan-JAK inhibitor targeting COVID-19-related acute lung injury.</p>
    Fórmula:C30H37N7O2
    Forma y color:Solid
    Peso molecular:527.66

    Ref: TM-T63709

  • Chroman 1
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    Chroman 1

    CAS:
    <p>Chroman 1 is a potent inhibitor of ROCK1 (IC50 = 52 pM) and ROCK2 (IC50 = 1 pM).</p>
    Fórmula:C24H28N4O4
    Pureza:99.67% - 99.84%
    Forma y color:Solid
    Peso molecular:436.5

    Ref: TM-T14960

  • BMS-932481
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    BMS-932481

    CAS:
    <p>BMS-932481 is a γ-secretase modulator.</p>
    Fórmula:C24H24FN7O
    Forma y color:Solid
    Peso molecular:445.49

    Ref: TM-T26864

  • GSK-3β inhibitor 8
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    GSK-3β inhibitor 8

    CAS:
    <p>GSK-3β inhibitor 8 (GSK3β Inhibitor XVIII) is a potent and selective GSK-3β inhibitor with an IC50 value of 64 nM.GSK-3β inhibitor 8 is a thienopyrimidine</p>
    Fórmula:C20H20ClN5OS
    Pureza:98.46%
    Forma y color:Solid
    Peso molecular:413.92

    Ref: TM-T35556

  • JAK-IN-4
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    JAK-IN-4

    CAS:
    <p>JAK-IN-4 is a prodrug of a JAK inhibitor, effective in murine collagen induced arthritis model.</p>
    Fórmula:C18H21N4Na2O6P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:466.341

    Ref: TM-T11705

  • ROCK2-IN-2
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    ROCK2-IN-2

    CAS:
    <p>ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of &lt;1 μM).</p>
    Fórmula:C18H12N6OS
    Pureza:99.65%
    Forma y color:Solid
    Peso molecular:360.39

    Ref: TM-T12747

  • Casein kinase 1δ-IN-10
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    Casein kinase 1δ-IN-10

    CAS:
    <p>Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).</p>
    Fórmula:C21H17N3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:359.38

    Ref: TM-T79697

  • FM-479
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    FM-479

    CAS:
    <p>FM-479, a structural analog of FM-381, lacks inhibition of JAK3/kinases within 100-300 nM, serving as FM-381's negative control.</p>
    Fórmula:C25H26N6O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:442.523

    Ref: TM-T22333

  • STAT3-IN-B9
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    STAT3-IN-B9

    CAS:
    <p>STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.</p>
    Fórmula:C20H13NO5S
    Pureza:98.19%
    Forma y color:Solid
    Peso molecular:379.39

    Ref: TM-T28865

  • TP0427736
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    TP0427736

    CAS:
    <p>TP0427736: ALK5 inhibitor, IC50=2.72 nM, 300x &gt; ALK3 selectivity; counters TGF-β in human cells, extends anagen in mice.</p>
    Fórmula:C14H10N4S2
    Pureza:97.26%
    Forma y color:Solid
    Peso molecular:298.39

    Ref: TM-T24897

  • ML115
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    ML115

    CAS:
    <p>ML115 is a potent and selective activator of transcription 3 (STAT3), with abn EC50 of 2.0 nM, and is inactive against the related STAT1 and NFκB anti-targets.</p>
    Fórmula:C15H15ClN2O4
    Pureza:99.97%
    Forma y color:Solid
    Peso molecular:322.74

    Ref: TM-T35544

  • MRK-560
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    MRK-560

    CAS:
    <p>MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.</p>
    Fórmula:C19H17ClF5NO4S2
    Pureza:98.87%
    Forma y color:Solid
    Peso molecular:517.92

    Ref: TM-T16133

  • LX7101
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    LX7101

    CAS:
    <p>LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 &lt;1 nM).</p>
    Fórmula:C23H29N7O3
    Pureza:99.08%
    Forma y color:Solid
    Peso molecular:451.52

    Ref: TM-T15798

  • Itacnosertib (hydrocholide)
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    Itacnosertib (hydrocholide)

    CAS:
    <p>Itacnosertib hydrochloride acts as an inhibitor targeting JAK2, ACVR1 (ALK2), and ALK5 [1].</p>
    Fórmula:C26H29ClN8O
    Forma y color:Solid
    Peso molecular:505.01

    Ref: TM-T84696

  • BMS-983970
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    BMS-983970

    CAS:
    <p>BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.</p>
    Fórmula:C26H26F4N4O3
    Forma y color:Solid
    Peso molecular:518.5

    Ref: TM-T14683