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Células madre y Derivados

Células madre y Derivados

Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.

Subcategorías de "Células madre y Derivados"

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Se han encontrado 695 productos de "Células madre y Derivados"

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  • WZ-2-033
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    WZ-2-033

    CAS:
    <p>WZ-2-033 is a potent STAT3 inhibitor. It inhibits proliferation, colony survival, migration, and invasion of MDA-MB-231, HCC70, and MDA-MB231-4175 cells, with IC50 values of 0.7, 1.3, and 1.3 μM respectively.</p>
    Fórmula:C25H18F3N3O4S
    Forma y color:Solid
    Peso molecular:513.49

    Ref: TM-T200925

  • STAT3-IN-8
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    STAT3-IN-8

    CAS:
    <p>"STAT3-IN-8 (compound H172) is a potent inhibitor of STAT3 with potential applications in cancer research [1]."</p>
    Fórmula:C19H7F7N2O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:444.26

    Ref: TM-T71550

  • PF-06263276
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    PF-06263276

    CAS:
    <p>PF-06263276 selectively inhibits pan-JAK with IC50: JAK1 (2.2 nM), JAK2 (23.1 nM), JAK3 (59.9 nM), TYK2 (29.7 nM).</p>
    Fórmula:C31H31FN8O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:566.63

    Ref: TM-T16488

  • PF-06648671
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    PF-06648671

    CAS:
    <p>PF-06648671 is a γ-secretase modulator for the treatment of neurodegenerative and/or neurological disorders.</p>
    Fórmula:C25H23ClF4N4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:538.92

    Ref: TM-T24621

  • TGFβ1-IN-1
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    TGFβ1-IN-1

    CAS:
    <p>TGFβ1-IN-1 is a TGF-β1 inhibitor that inhibits the production of TGF-β1-induced fibrosis markers (α-SMA and fibronectin) and can be used in cancer research.</p>
    Fórmula:C22H24N2O3
    Pureza:99.89% - 99.89%
    Forma y color:Solid
    Peso molecular:364.438

    Ref: TM-T61389

  • GSK-3β inhibitor 20
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    GSK-3β inhibitor 20

    CAS:
    <p>GSK-3β inhibitor20 (compound 3A) is an effective inhibitor of GSK-3β, exhibiting an IC50 value of 74.4 nM.</p>
    Fórmula:C22H21N5O2S
    Forma y color:Solid
    Peso molecular:419.50

    Ref: TM-T200457

  • HDAC6-IN-9
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    HDAC6-IN-9

    CAS:
    <p>HDAC6-IN-9 is a γ-secretase modulator that can significantly reduce the level of Aβ42 in mouse brain and can be used to study neurological diseases.</p>
    Fórmula:C19H16N2O3
    Pureza:98.84%
    Forma y color:Solid
    Peso molecular:320.34

    Ref: TM-T60856

  • DAPM
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    DAPM

    CAS:
    <p>DAPM (gamma-Secretase Inhibitor XVI) is a Notch pathway inhibitor with anticancer activity and antiproliferative effects.</p>
    Fórmula:C20H20F2N2O4
    Pureza:99.76%
    Forma y color:Solid
    Peso molecular:390.38

    Ref: TM-T86161

  • Aβ42-IN-1
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    Aβ42-IN-1

    CAS:
    <p>Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).</p>
    Fórmula:C29H27ClN4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:499

    Ref: TM-T10211

  • Tyk2-IN-20
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    Tyk2-IN-20

    CAS:
    <p>Tyk2-IN-20 (Example 289) is an effective inhibitor of Tyk2 with an IC50 value below 5 nM. Additionally, it inhibits JAK1, JAK2, and JAK3 with IC50 values under 100 nM. This compound is utilized for the research of inflammatory diseases.</p>
    Fórmula:C24H25N7O2
    Forma y color:Solid
    Peso molecular:443.50

    Ref: TM-T201155

  • TYK2 ligand 2
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    TYK2 ligand 2

    CAS:
    <p>TYK2ligand 2 is the TYK2 ligand of PROTACTYD-68. TYD-68 is a highly potent and selective CRBN-recruiting TYK2 PROTAC degrader with a DC50 value of 0.42 nM.</p>
    Fórmula:C24H20FN7O4
    Forma y color:Solid
    Peso molecular:489.458

    Ref: TM-T206678

  • TEAD-IN-20
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    TEAD-IN-20

    CAS:
    <p>TEAD-IN-20 is a TEAD inhibitor with IC50 values of 0.021 μM in TEAD4 FRET and 0.044 μM in TEAD4 MCF7-Tead cell lines. It has potential applications in cancer research.</p>
    Fórmula:C20H19F3N4O3
    Forma y color:Solid
    Peso molecular:420.39

    Ref: TM-T207373

  • Logo de CymitQuimica
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    JAK-IN-19

    <p>JAK-IN-19 inhibits JAK (pIC50: 7.2, 7.7), less so for VEGFR2 (7.0) and Aurora B (5.8).</p>
    Fórmula:C26H36FN5O2
    Forma y color:Solid
    Peso molecular:469.59

    Ref: TM-T63026

  • iBFAR2
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    iBFAR2

    CAS:
    <p>iBFAR2, an inhibitor of BFAR, restores the CD8+ tumor-resident memory T cell subset against solid tumors. It promotes the binding of JAK2-STAT1 and enhances the phosphorylation of STAT1.</p>
    Fórmula:C19H15F3N2O2
    Forma y color:Solid
    Peso molecular:360.33

    Ref: TM-T204531

  • CEE321
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    CEE321

    CAS:
    <p>CEE321 is an effective pan-JAK inhibitor with an IC50 of 54 nM. It effectively inhibits biomarkers associated with atopic dermatitis.</p>
    Fórmula:C18H16ClN5O
    Forma y color:Solid
    Peso molecular:353.806

    Ref: TM-T204824

  • Cenacitinib
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    Cenacitinib

    CAS:
    <p>Cenacitinib is an effective inhibitor of Janus kinase (Janus kinase) and possesses anti-inflammatory activity.</p>
    Fórmula:C19H19F2N7O3
    Forma y color:Solid
    Peso molecular:431.40

    Ref: TM-T201149

  • (R)-9b
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    (R)-9b

    CAS:
    <p>(R)-9b is an effective inhibitor of the ACK1 tyrosine kinase (IC50=56 nM) and exhibits anticancer activity. It selectively targets ACK1 but also inhibits kinases in the JAK family, specifically JAK2 and Tyk2. (R)-9b is used in research related to hormone-regulated cancers, such as prostate cancer and breast cancer.</p>
    Fórmula:C20H27ClN6O
    Forma y color:Solid
    Peso molecular:402.92

    Ref: TM-T201776

  • Carboxylesterase-IN-3
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    Carboxylesterase-IN-3

    CAS:
    <p>Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.</p>
    Fórmula:C11H6Cl2N4OS
    Pureza:97.49% - 98.47%
    Forma y color:Solid
    Peso molecular:313.16

    Ref: TM-T60788

  • STAT3-IN-35
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    STAT3-IN-35

    CAS:
    <p>STAT3-IN-35 is a STAT3 inhibitor that binds to the SH2 domain. This compound inhibits the phosphorylation of STAT3 and exhibits antiproliferative activity in triple-negative breast cancer (TNBC) cell lines. Additionally, STAT3-IN-35 has demonstrated toxicity and potent antitumor activity in TNBC xenograft models.</p>
    Fórmula:C21H23NO4
    Forma y color:Solid
    Peso molecular:353.41

    Ref: TM-T200468

  • YLIU-4-105-1
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    YLIU-4-105-1

    CAS:
    <p>YLIU-4-105-1 is a type II JAK2 inhibitor. Demonstrating in vivo pharmacological activity, YLIU-4-105-1 reduces splenic weight, decreases blood reticulocyte counts in a dose-dependent manner, and inhibits pSTAT5.</p>
    Fórmula:C32H34F3N7O2
    Forma y color:Solid
    Peso molecular:605.65

    Ref: TM-T201176