Células madre y Derivados
Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.
Subcategorías de "Células madre y Derivados"
- Gamma-secretasa(59 productos)
- Hedgehog / Smoothened(44 productos)
- Hippo pathway(6 productos)
- JAK(245 productos)
- Porcupine (Puerco espín)(9 productos)
- ROCK(70 productos)
- STAT(98 productos)
- Células madre(486 productos)
- TGF-beta / Smad(58 productos)
- Wnt / beta-catenina(66 productos)
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Se han encontrado 695 productos de "Células madre y Derivados"
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Casein kinase 1δ-IN-7
CAS:<p>Casein kinase 1δ-IN-7 is a Casein kinase 1δ inhibitor for neurodegenerative diseases such as Alzheimer's disease.</p>Fórmula:C17H14N4O2SPureza:98.6%Forma y color:SolidPeso molecular:338.38SJ1008030
CAS:<p>SJ1008030, a JAK2 PROTAC, degrades JAK2; EC50: 5.4 nM, IC50: 32.09 nM in MHH-CALL-4 cells for leukemia research.</p>Fórmula:C42H43N13O7SForma y color:SolidPeso molecular:873.94JAK1/TYK2-IN-1
CAS:<p>JAK1/TYK2-IN-1 is a dual inhibitor of TYK2 and JAK1 ( IC 50 = 29 and 41 nM respectively).</p>Fórmula:C18H20F3N7OForma y color:SolidPeso molecular:407.401YAP/TEAD-IN-1
<p>YAP/TEAD-IN-1 (compound 4) is a potent inhibitor of YAP and TEAD, exhibiting antioxidant properties. It demonstrates antiproliferative effects on tumor cells while showing minimal cytotoxic activity towards normal human cells.</p>Fórmula:C32H30N8OForma y color:SolidPeso molecular:542.634FDA-Approved Kinase Inhibitor Library
<p>A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.</p>Forma y color:LiquidEpigenetics Compound Library
<p>Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new</p>Forma y color:Odour SolidCIA-1 (Free base)
CAS:<p>CIA-1, a COUP-TFII inhibitor, has IC50 of 1.2-7.6 μM in prostate cancer cells; inhibits tumor growth in mouse prostate cancer.</p>Fórmula:C17H19N3O2SPureza:99%Forma y color:SolidPeso molecular:329.42Tyrosine Kinase Inhibitor Library
<p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>Forma y color:Odour SolidKinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Forma y color:Odour SolidYAP-IN-1
<p>YAP-IN-1 (Compound (+)-1) is an autophagy inhibitor specifically targeting YAP1. It binds to the Hippo pathway transcription factor YAP1 with a Kd of 9.13 μM, promoting its degradation through the chaperone-mediated autophagy (CMA) pathway. This process inhibits the Rab7-mediated fusion of autophagosomes with lysosomes and decreases autophagy levels without affecting lysosomal function. YAP-IN-1 shows potential for cancer research, including in hepatocellular carcinoma and breast cancer.</p>Forma y color:Odour SolidSJ10542
CAS:<p>SJ10542: potent JAK2/3-targeting PG-PROTAC; DC50s: JAK2 - 14 nM, JAK3 - 11 nM, JAK2-fusion ALL - 24 nM; CRBN recruiter.</p>Fórmula:C41H46N12O5SForma y color:SolidPeso molecular:818.95FRM-024
CAS:<p>FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment of</p>Fórmula:C22H22ClN5O2Forma y color:SolidPeso molecular:423.91(R),2(S)-epoxy Cannabidiol
CAS:<p>1(R),2(S)-epoxy Cannabidiol (Compound 2a) is a structural analog of phytocannabinoids, exhibiting significant inhibitory activity on the Wnt/β-catenin pathway. It holds potential for research as a neuroprotective agent.</p>Fórmula:C21H30O3Forma y color:SolidPeso molecular:330.46Foxy-5 Ammonium Salt
<p>Foxy-5 Ammonium Salt, a WNT5A mimetic, blocks epithelial cancer cell migration without β-catenin impact and curbs prostate cancer spread.</p>Fórmula:C26H46N7O12S2Pureza:97.70%Forma y color:SolidPeso molecular:712.26YAP-TEAD-IN-1 acetate
<p>YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.</p>Fórmula:C95H148ClN23O23S2Pureza:98.11% - 99.57%Forma y color:SoildPeso molecular:2079.92Carboxylesterase-IN-2
CAS:<p>Carboxylesterase-IN-2 is a potent Carboxylesterase Notum inhibitor (IC50 <= 10 nM).Carboxylesterase-IN-2 has potential for the study of cancer diseases.</p>Fórmula:C13H12N4OSPureza:99.92%Forma y color:SoildPeso molecular:272.33Fresolimumab
CAS:<p>Fresolimumab (GC1008) is a human monoclonal antibody targeting active TGFβ1, TGFβ2, TGFβ3, studied for cancer and focal segmental glomerulosclerosis.</p>Pureza:> 95% - > 95%Forma y color:LiquidPeso molecular:144.4 kDaTEAD-IN-19
<p>TEAD-IN-19 (Compound 1l) is a transcriptional inhibitor of TEAD, showing inhibition rates of 38.5%, 36.2%, 57.8%, and 71.3% for TEAD1, TEAD2, TEAD3, and TEAD4, respectively, at 10 μM. It exhibits strong antiproliferative and antimigratory effects on prostate cancer cell lines and significantly reduces the expression of TEAD-regulated downstream genes. TEAD-IN-19 holds potential for research in the field of cancer therapeutics.</p>Forma y color:Odour SolidNotch 1 TFA
<p>Notch 1 TFA encodes a member of the NOTCH family of proteins.</p>Fórmula:C64H98N15F3O25S3Pureza:98%Forma y color:SolidPeso molecular:1614.81LH168
<p>LH168 is a potent and selective probe for WDR5, with a SPR Kd value of 13 nM.</p>Fórmula:C29H31F3N6O2SForma y color:SolidPeso molecular:584.66
