Células madre y Derivados
Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.
Subcategorías de "Células madre y Derivados"
- Gamma-secretasa(62 productos)
- Hedgehog / Smoothened(49 productos)
- Hippo pathway(7 productos)
- JAK(243 productos)
- Porcupine (Puerco espín)(9 productos)
- ROCK(61 productos)
- STAT(100 productos)
- Células madre(191 productos)
- TGF-beta / Smad(60 productos)
- Wnt / beta-catenina(61 productos)
Mostrar 2 subcategorías más
Se han encontrado 474 productos de "Células madre y Derivados"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
(Z)-LFM-A13
CAS:(Z)-LFM-A13(IC50=2.5 μM), a specific Bruton's tyrosine kinase (BTK), is more than 100-fold specificity than other protein kinases, such as JAK1, JAK2, HCK, EGFR, and IRK.Fórmula:C11H8Br2N2O2Pureza:99.88%Forma y color:SolidPeso molecular:360VP3.15 dihydrobromide
CAS:VP3.15 dihydrobromide: potent, oral, CNS-penetrant PDE7/GSK3 inhibitor; IC50s: PDE7- 1.59 μM, GSK- 0.88 μM.Fórmula:C20H24Br2N4OSPureza:99.67% - ≥95%Forma y color:SolidPeso molecular:528.3LGK974
CAS:LGK974 (NVP-LGK974) is a selective PORCN inhibitor that blocks Wnt signaling, used in metastatic colorectal and head/neck cancer trials. IC50: 0.4 nM.Fórmula:C23H20N6OPureza:98.8% - >99.99%Forma y color:SolidPeso molecular:396.44Ref: TM-T2618
1mg46,00€2mg62,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg156,00€25mg288,00€50mg515,00€100mg737,00€PF-670462
CAS:PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1ε in isolated enzyme preparations.Fórmula:C19H22Cl2FN5Pureza:99.42% - 99.72%Forma y color:SolidPeso molecular:410.32MYF-01-37
CAS:MYF-01-37 (1-[3-Methyl-3-[3-(trifluoromethyl)anilino]pyrrolidin-1-yl]prop-2-en-1-one) is a novel covalent TEAD inhibitor.Fórmula:C15H17F3N2OPureza:99.46% - 99.5%Forma y color:SolidPeso molecular:298.3Ref: TM-T22372
2mg38,00€5mg57,00€1mL*10mM (DMSO)63,00€10mg90,00€25mg166,00€50mg281,00€100mg421,00€500mg888,00€AT9283
CAS:AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).Fórmula:C19H23N7O2Pureza:99.83% - 99.98%Forma y color:SolidPeso molecular:381.43Ref: TM-T3068
2mg39,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg111,00€25mg231,00€50mg371,00€100mg595,00€200mg833,00€CEP-33779
CAS:CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.Fórmula:C24H26N6O2SPureza:98.24% - ≥95%Forma y color:SolidPeso molecular:462.57Ref: TM-T6122
1mg43,00€2mg56,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg137,00€25mg231,00€50mg356,00€100mg530,00€500mg1.153,00€Baricitinib phosphate
CAS:Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.Fórmula:C16H20N7O6PSPureza:99.4% - 99.91%Forma y color:SolidPeso molecular:469.41Ref: TM-T2360
5mg40,00€1mL*10mM (DMSO)46,00€10mg52,00€25mg73,00€50mg93,00€100mg105,00€200mg157,00€500mg260,00€WHI-P97 HCl
WHI-P97 HCl is a potent and selective JAK-3 inhibitor.Fórmula:C16H14Br2ClN3O3Pureza:99.49%Forma y color:SolidPeso molecular:491.56Ref: TM-T4657L
2mg34,00€5mg48,00€1mL*10mM (DMSO)73,00€10mg86,00€25mg138,00€50mg182,00€100mg261,00€200mg371,00€SJ000291942
CAS:SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.Fórmula:C16H15FN2O4Pureza:99.66%Forma y color:SolidPeso molecular:318.3Ref: TM-T4662
1mg34,00€2mg44,00€5mg63,00€1mL*10mM (DMSO)71,00€10mg100,00€25mg205,00€50mg349,00€100mg557,00€200mg790,00€ZINC00881524
CAS:ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.
Fórmula:C21H20N2O3SPureza:99.48%Forma y color:SolidPeso molecular:380.46Abrocitinib
CAS:Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).Fórmula:C14H21N5O2SPureza:99.09% - 99.91%Forma y color:SolidPeso molecular:323.41LSKL, Inhibitor of Thrombospondin TSP-1 2TFA
LSKL, Inhibitor of Thrombospondin TSP-1 acetate is activation of TGF-β .Fórmula:C25H44F6N6O9Pureza:99.75%Forma y color:SolidPeso molecular:686.64Ref: TM-T7676
2mg42,00€5mg54,00€10mg84,00€1mL*10mM (DMSO)93,00€25mg138,00€50mg207,00€100mg316,00€200mg442,00€SC99
CAS:SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.Fórmula:C15H8Cl2FN3OPureza:99.56%Forma y color:SolidPeso molecular:336.15Ref: TM-T8719
1mg43,00€5mg87,00€1mL*10mM (DMSO)94,00€10mg133,00€25mg227,00€50mg344,00€100mg429,00€200mg597,00€Kartogenin
CAS:Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.Fórmula:C20H15NO3Pureza:96.25% - 97.79%Forma y color:SolidPeso molecular:317.34TBB
CAS:TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).
Fórmula:C6HBr4N3Pureza:98.51% - 99.45%Forma y color:Off-White SolidPeso molecular:434.71ITD-1
CAS:ITD-1 is a potent and highly selective TGFβ pathway inhibitor.Fórmula:C27H29NO3Pureza:99.89% - >99.99%Forma y color:SolidPeso molecular:415.52WP1066
CAS:WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Fórmula:C17H14BrN3OPureza:98.92% - 99.73%Forma y color:SolidPeso molecular:356.22Galunisertib
CAS:Galunisertib (LY2157299) is a selective TGF-β receptor type I (TGF-βRI) inhibitor. Galunisertib has antitumor activity. Cost-effective and quality-assured.Fórmula:C22H19N5OPureza:97.09% - 99.98%Forma y color:SolidPeso molecular:369.42Ref: TM-T2510
5mg46,00€10mg52,00€1mL*10mM (DMSO)52,00€25mg84,00€50mg114,00€100mg178,00€200mg269,00€500mg442,00€1g657,00€
