Células madre y Derivados
Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.
Subcategorías de "Células madre y Derivados"
- Gamma-secretasa(62 productos)
- Hedgehog / Smoothened(49 productos)
- Hippo pathway(7 productos)
- JAK(243 productos)
- Porcupine (Puerco espín)(9 productos)
- ROCK(61 productos)
- STAT(100 productos)
- Células madre(189 productos)
- TGF-beta / Smad(60 productos)
- Wnt / beta-catenina(61 productos)
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Se han encontrado 472 productos de "Células madre y Derivados"
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YAP/TAZ inhibitor-2
CAS:Potent oral TEAD-YAP/TAZ inhibitor-2 with 3 nM EC50; exhibits anti-proliferative and antitumor effects.Fórmula:C19H14F4N4OPureza:98.65%Forma y color:SoildPeso molecular:390.33Ref: TM-T60218
1mg87,00€2mg113,00€5mg177,00€1mL*10mM (DMSO)197,00€10mg281,00€25mg475,00€50mg687,00€100mg964,00€500mg1.918,00€RO7185876
CAS:RO7185876 is a selective gamma secretase modulator, which can be used in the study of Alzheimer's disease.Fórmula:C25H28F3N7Pureza:99.50%Forma y color:SolidPeso molecular:483.532VT107
CAS:VT107 is a potent pan-TEAD autopalmitoylation inhibitor. VT-107 can be used in cancer therapy research.Cost-effective and quality-assured.Fórmula:C25H20F3N3OPureza:99.72% - 99.92%Forma y color:SolidPeso molecular:435.44Ref: TM-T35545
1mg130,00€5mg314,00€1mL*10mM (DMSO)343,00€10mg477,00€25mg768,00€50mg1.045,00€100mg1.406,00€200mg1.882,00€Sulindac EP Impurity C-d3
CAS:Sulindac EP Impurity C-d3 is a deuterated compound of Sulindac EP Impurity C. Sulindac EP Impurity C has a CAS number of 32004-67-4. (E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM) that selectively reduces Aβ42 production in favor of shorter Aβ species. (E/Z)-Sulindac sulfide can be used for researching Alzheimer's disease [1].Fórmula:C20H14D3FO2SForma y color:SolidPeso molecular:343.43NVP-BSK805
CAS:NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.Fórmula:C27H28F2N6OPureza:98%Forma y color:SolidPeso molecular:490.55Nisevokitug
CAS:Nisevokitug (anti-TGF-β mAb) neutralizes TGF-β and is being studied for its ability to modulate the immunosuppressive tumor microenvironment.Pureza:95%Forma y color:LiquidPeso molecular:143.51 kDaDilpacimab
CAS:Dilpacimab (ABT165) is a dual-variable antibody that targets DLL4 and VEGF pathways, showing potential in cancer research by blocking angiogenesis and Notch.Pureza:95% - 97.7% (SDS-PAGE); 95.6% (SEC-HPLC)Forma y color:LiquidLivmoniplimab
CAS:Livmoniplimab (ABBV-151; ARGX-115) is a humanised monoclonal antibody targeting LRRC32 (GARP)/TGFβ1, which blocks TGFβ1 release mediated by LRRC32Pureza:95%Forma y color:LiquidPeso molecular:~150 kDaGinisortamab
CAS:Ginisortamab (UCB6114) is a fully humanized monoclonal antibody targeting Gremlin-1, IC50=8.2 nM and 9 nM against human and mouse Gremlin-1, respectively.Pureza:95% - 96.0% (SDS-PAGE); 97.0% (SEC-HPLC)Forma y color:LiquidPeso molecular:147.55 kDaTarextumab
CAS:Tarextumab is an anti-Notch2/3 mAb, a promising candidate for breast, lung, ovarian, and pancreatic cancers.Pureza:95%Forma y color:LiquidPeso molecular:~150 kDaTrevogrumab
CAS:Trevogrumab is a human monoclonal antibody that inhibits myostatin (GDF8) to promote muscle growth, and is under research for treating age-related muscle loss (sarcopenia).Pureza:95% - 97.6% (SDS-PAGE); 95.9% (SEC-HPLC)Forma y color:LiquidPeso molecular:144.02 kDaMetelimumab
CAS:Metelimumab (CAT-192) is a humanised monoclonal antibody targeting TGFβ1, which can be used to study diffuse systemic sclerosis (d-SSc).Pureza:95%Forma y color:LiquidPeso molecular:~150 kDa(3S,4S)-Tofacitinib
CAS:(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.Fórmula:C16H20N6OPureza:98%Forma y color:SolidPeso molecular:312.37TEAD-IN-2
CAS:TEAD-IN-2 is a potent and bifunctional TEAD inhibitor to induce TEAD protein degradation via the ubiquitination pathway, with anticancer potential.Fórmula:C16H18BrF3N2OForma y color:SolidPeso molecular:391.23SD-1029
CAS:SD-1029 is a JAK2 inhibitor and a novel Stat3 activation inhibitor that inhibits Stat3 phosphorylation and JAK-STAT signaling.Fórmula:C25H32Br2Cl2N2O3Forma y color:SolidPeso molecular:639.25γ-Secretase modulator 11
CAS:5-{8-[(3,4'-Difluoro[1,1'-biphenyl]-4-yl)methoxy]-2-methylimidazo[1,2-a]pyridin-3-yl}-N-methylpyridine-2-carboxamide (1o) exhibited high in vitro potency andFórmula:C28H22F2N4O2Forma y color:SolidPeso molecular:484.5JA310
CAS:JA310 is a highly selective inhibitor of the MST3 kinase, demonstrating significant cellular potency with an EC50 value of 106 nM [1].Fórmula:C17H19N7OForma y color:SolidPeso molecular:337.38CP-690550A
CAS:Cp-690550a is a novel JAK3 inhibitor, which is used to treat rheumatoid arthritis, graft rejection, psoriasis, and other immune-mediated diseases.Fórmula:C15H21N5O2Forma y color:SolidPeso molecular:303.36GDC-4379
CAS:GDC-4379 is a JAK1 inhibitor that can be used to study asthma.Fórmula:C21H18ClF2N7O3Forma y color:SolidPeso molecular:489.86SYK/JAK-IN-1
CAS:SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.Fórmula:C24H26N8O3Forma y color:SolidPeso molecular:474.52
