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Células madre y Derivados

Células madre y Derivados

Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.

Subcategorías de "Células madre y Derivados"

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Se han encontrado 692 productos de "Células madre y Derivados"

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  • TK4g
    Targetmol
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    TK4g

    CAS:
    <p>TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) &amp; 15.80 nM (JAK3); promising for lymphoid diseases &amp; leukemia research.</p>
    Fórmula:C19H19N3O4S
    Forma y color:Solid
    Peso molecular:385.44

    Ref: TM-T61698

  • γ-Secretase modulator 4
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    γ-Secretase modulator 4

    CAS:
    <p>γ-Secretase modulator 4 is a potent γ-secretase modulator, reduces the Aβ42 level with IC50s of 0.017 μM and 0.014 μM in mouse and human, respectively.</p>
    Fórmula:C23H19FN4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:402.42

    Ref: TM-T11361

  • tCFA15
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    tCFA15

    CAS:
    tCFA15: A trimethylated long-chain fatty alcohol with a 15-carbon side chain; may regulate Notch signaling and neuron differentiation.
    Fórmula:C24H44O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:364.61

    Ref: TM-T13917

  • γ-secretase modulator 2
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    γ-secretase modulator 2

    CAS:
    <p>Gamma-secretase modulator 2 selectively targets Alzheimer's by reducing Aβ(1-42), aiding in prevention and treatment.</p>
    Fórmula:C25H22F4N6O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:514.47

    Ref: TM-T11359

  • JAK-IN-18
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    JAK-IN-18

    CAS:
    <p>"JAK-IN-18: potent JAK inhibitor for eye, skin, respiratory disease research (WO2018204238A1, comp 1)."</p>
    Fórmula:C27H28F2N6O3
    Forma y color:Solid
    Peso molecular:522.55

    Ref: TM-T63658

  • LY-411575 isomer 1
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    LY-411575 isomer 1

    CAS:
    <p>LY-411575 isomer 1 is a potent γ-secretase inhibitor. LY-411575 isomer 1 is an isomer of LY411575.</p>
    Fórmula:C26H23F2N3O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:479.48

    Ref: TM-T11903

  • JAK3-IN-12
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    JAK3-IN-12

    CAS:
    <p>JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.</p>
    Fórmula:C19H19N5O4S
    Forma y color:Solid
    Peso molecular:413.45

    Ref: TM-T62114

  • ELN318463
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    ELN318463

    CAS:
    <p>ELN 318463 selectively inhibits γ-secretase; EC50: 12 nM (PS1), 656 nM (PS2); 51x more selective for PS1; targets APP.</p>
    Fórmula:C19H20BrClN2O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:471.8

    Ref: TM-T11178

  • Tyk2-IN-5
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    Tyk2-IN-5

    CAS:
    Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).
    Fórmula:C21H19FN8O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:434.43

    Ref: TM-T13234

  • JAK-IN-14
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    JAK-IN-14

    CAS:
    <p>JAK-IN-14 (compound 16) is a specific JAK1 inhibitor. It prevents JAK1 phosphorylation by binding to the active site of JAK in immune, inflammation and cancer.</p>
    Fórmula:C19H15FN4O
    Pureza:98.27%
    Forma y color:Solid
    Peso molecular:334.35

    Ref: TM-T9764

  • OICR-0547
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    OICR-0547

    CAS:
    <p>OICR-0547 is an inactive derivative of OICR-9429 and is commonly used as a negative control for OICR-9429.</p>
    Fórmula:C28H29F3N4O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:542.55

    Ref: TM-T12290

  • EP009
    Targetmol
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    EP009

    CAS:
    <p>EP009, a novel, selective, and orally active inhibitor of JAK3, induces therapeutic response in T-cell malignancies.</p>
    Fórmula:C14H24O2
    Forma y color:Solid
    Peso molecular:224.34

    Ref: TM-T27274

  • Tyk2-IN-7
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    Tyk2-IN-7

    CAS:
    Tyk2-IN-7 is an inhibitor of TYK2 JH2, binds to the TYK2 JH2 domain (IC50: 0.00053 μM; Ki.app: 0.00007 μM).
    Fórmula:C18H15D3N6O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:401.46

    Ref: TM-T13235

  • 3F8
    Targetmol
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    3F8

    CAS:
    <p>3F8 is a selective GSK-3β inhibitor that can be used as a new tool and potential therapeutic candidate compound for GSK3-related diseases, and can be used in</p>
    Fórmula:C15H14N2O4
    Pureza:98.14% - 98.25%
    Forma y color:Solid
    Peso molecular:286.28

    Ref: TM-T22180

  • MS-1020
    Targetmol
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    MS-1020

    CAS:
    MS-1020 inhibits JAK3/STAT3, blocks active JAK3, suppresses JAK3/STAT5 signaling, and targets STAT3 in certain cells.
    Fórmula:C21H18N2O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:346.38

    Ref: TM-T28113

  • 1,2,3,4,5,6-Hexabromocyclohexane
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    1,2,3,4,5,6-Hexabromocyclohexane

    CAS:
    <p>Inhibits JAK2 autophosphorylation; non-cytotoxic at 100μM; 1μM reduces activity by 50%, 50μM nearly abolishes it.</p>
    Fórmula:C6H6Br6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:557.54

    Ref: TM-T22462

  • INCB16562
    Targetmol
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    INCB16562

    CAS:
    <p>INCB16562: oral JAK1/2 inhibitor, halts IL-6/STAT3 in myeloma cells, boosts drug efficacy, stunts myeloma in mice.</p>
    Fórmula:C19H11Cl2N5
    Forma y color:Solid
    Peso molecular:380.23

    Ref: TM-T68306

  • JAK3-IN-9
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    JAK3-IN-9

    CAS:
    <p>JAK3-IN-9, potent JAK3 inhibitor, IC50 of 1.7 nM, highly selective, low toxicity, orally bioavailable, shows anti-arthritis activity.</p>
    Fórmula:C17H23N5O4S
    Forma y color:Solid
    Peso molecular:393.46

    Ref: TM-T61814

  • RR-11a analog
    Targetmol
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    RR-11a analog

    CAS:
    <p>RR-11a (aza-peptide) inhibits asparaginyl endopeptidase: IC50 - 4.5 nM (T. Vaginalis, I. ricinus), 31 nM (S. mansoni).</p>
    Fórmula:C22H29N5O8
    Pureza:98.80%
    Forma y color:Solid
    Peso molecular:491.49

    Ref: TM-T12770

  • TGFβRI-IN-1
    Targetmol
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    TGFβRI-IN-1

    CAS:
    <p>TGFβRI-IN-1 is an oral active and selective inhibitor of TGFβ receptor type I (TGFβRI) kinase(IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII,</p>
    Fórmula:C20H14D3N5O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:362.4

    Ref: TM-T13137