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Células madre y Derivados

Células madre y Derivados

Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.

Subcategorías de "Células madre y Derivados"

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Se han encontrado 693 productos de "Células madre y Derivados"

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  • YAP-TEAD-IN-2
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    YAP-TEAD-IN-2

    CAS:
    <p>YAP-TEAD-IN-2 (compound 6) serves as a potent inhibitor of the YAP-TEAD protein-protein interaction (PPI), demonstrating an inhibitory concentration 50 (IC50)</p>
    Fórmula:C25H24ClFN2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:470.92

    Ref: TM-T72888

  • Tubulin/JAK2-IN-1
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    Tubulin/JAK2-IN-1

    CAS:
    <p>Tubulin/JAK2-IN-1 (compound 7g) serves as a potent dual inhibitor targeting both Janus kinase 2 (JAK2) and microtubules, demonstrating significant</p>
    Fórmula:C22H20N6O3
    Forma y color:Solid
    Peso molecular:416.43

    Ref: TM-T80921

  • QL-1200186
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    QL-1200186

    CAS:
    <p>QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-γ (IFNγ) production following</p>
    Fórmula:C26H27N7O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:485.54

    Ref: TM-T81331

  • JAK kinase-IN-1
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    JAK kinase-IN-1

    CAS:
    <p>JAK kinase-IN-1 (Example 1) functions as a potent inhibitor targeting the JAK family, which includes TYK2, JAK1, JAK2, and JAK3, with IC50 values of 4.2 nM, 32</p>
    Fórmula:C17H19F2N7OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:407.44

    Ref: TM-T79807

  • Yhhu-3792 hydrochloride
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    Yhhu-3792 hydrochloride

    CAS:
    <p>Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].</p>
    Fórmula:C24H25ClN4O2
    Forma y color:Solid
    Peso molecular:436.93

    Ref: TM-T84890

  • Casein kinase 1δ-IN-4
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    Casein kinase 1δ-IN-4

    CAS:
    <p>"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."</p>
    Fórmula:C16H12N6S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:320.37

    Ref: TM-T79127

  • STAT3-IN-B9
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    STAT3-IN-B9

    CAS:
    <p>STAT3-IN-B9 (B9) is an inhibitor of abnormal STAT3 activation and inhibits the proliferation of tumor cells including MDA-MB-468, MDA-MB-231, and DU145.</p>
    Fórmula:C20H13NO5S
    Pureza:98.19%
    Forma y color:Solid
    Peso molecular:379.39

    Ref: TM-T28865

  • LX7101
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    LX7101

    CAS:
    LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).
    Fórmula:C23H29N7O3
    Pureza:99.08%
    Forma y color:Solid
    Peso molecular:451.52

    Ref: TM-T15798

  • Myristoyl tetrapeptide-12
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    Myristoyl tetrapeptide-12

    CAS:
    <p>Myristoyl Tetrapeptide-12 activates SMAD2 and facilitates the association of SMAD3 with DNA, promoting eyelash hair growth [1] [2].</p>
    Fórmula:C32H63N7O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:625.89

    Ref: TM-T80628

  • ROCK-IN-7
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    ROCK-IN-7

    CAS:
    <p>ROCK-IN-7 (compound 9) serves as a ROCK kinase inhibitor and is utilized in the investigation of ocular conditions, including glaucoma and retinal diseases [1].</p>
    Fórmula:C17H17N3O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:327.4

    Ref: TM-T79080

  • BRD5648
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    BRD5648

    CAS:
    <p>BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705.</p>
    Fórmula:C20H23N3O
    Pureza:99.89%
    Forma y color:Solid
    Peso molecular:321.42

    Ref: TM-T10608

  • JAK-IN-26
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    JAK-IN-26

    CAS:
    <p>JAK-IN-26 (compound 2) is an orally active inhibitor of the Janus kinase (JAK) enzyme with favorable pharmacokinetic properties, exhibiting potency in</p>
    Fórmula:C22H24N6O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:420.46

    Ref: TM-T78189

  • inS3-54A18
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    inS3-54A18

    CAS:
    <p>inS3-54A18 is an effective inhibitor of STAT3. inS3-54A18 has anticancer effects.</p>
    Fórmula:C23H16ClNO2
    Pureza:99.68%
    Forma y color:Solid
    Peso molecular:373.83

    Ref: TM-T15582

  • FM-479
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    FM-479

    CAS:
    <p>FM-479, a structural analog of FM-381, lacks inhibition of JAK3/kinases within 100-300 nM, serving as FM-381's negative control.</p>
    Fórmula:C25H26N6O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:442.523

    Ref: TM-T22333

  • Casein kinase 1δ-IN-5
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    Casein kinase 1δ-IN-5

    CAS:
    <p>Casein kinase 1δ-IN-5 is a potent and selective CK-1δ inhibitor, exhibiting an IC50 of 47 nM, and demonstrates neuroprotective and anti-inflammatory effects in</p>
    Fórmula:C16H11F3N2OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:336.33

    Ref: TM-T79154

  • JW 67
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    JW 67

    CAS:
    <p>JW 67 is an inhibitor of canonical Wnt pathway signaling.</p>
    Fórmula:C21H18N2O6
    Pureza:99.02%
    Forma y color:Solid
    Peso molecular:394.38

    Ref: TM-T22884

  • A 1070722
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    A 1070722

    CAS:
    <p>A 1070722: potent GSK-3 inhibitor, Ki = 0.6 nM for both α/β isoforms, crosses BBB, potential brain GSK-3 PET radiotracer.</p>
    Fórmula:C17H13F3N4O2
    Pureza:99.9%
    Forma y color:Solid
    Peso molecular:362.31

    Ref: TM-T10202

  • JAK-IN-31
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    JAK-IN-31

    CAS:
    <p>JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 µM for JAK1, ≤0.01 µM for JAK2, 0.01-0.1 µM for JAK3, and ≤0.01 µM for Tyk2,</p>
    Fórmula:C21H19N7O2S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:465.55

    Ref: TM-T79882

  • 3,7-DMF
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    3,7-DMF

    CAS:
    3,7-Dimethylfumarate (3,7-DMF) serves as an oral inhibitor of transforming growth factor-beta 1 (TGF-β1)-mediated hepatic stellate cell (HSC) activation.
    Fórmula:C17H14O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:282.29

    Ref: TM-T79603

  • ROCK2-IN-2
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    ROCK2-IN-2

    CAS:
    <p>ROCK2-IN-2 is a selective inhibitor of ROCK2 (IC50 of &lt;1 μM).</p>
    Fórmula:C18H12N6OS
    Pureza:99.65%
    Forma y color:Solid
    Peso molecular:360.39

    Ref: TM-T12747