Células madre y Derivados
Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.
Subcategorías de "Células madre y Derivados"
- Gamma-secretasa(61 productos)
- Hedgehog / Smoothened(49 productos)
- Hippo pathway(7 productos)
- JAK(243 productos)
- Porcupine (Puerco espín)(9 productos)
- ROCK(62 productos)
- STAT(98 productos)
- Células madre(198 productos)
- TGF-beta / Smad(59 productos)
- Wnt / beta-catenina(59 productos)
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Se han encontrado 480 productos de "Células madre y Derivados"
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Fresolimumab
CAS:Fresolimumab (GC1008) is a human monoclonal antibody targeting active TGFβ1, TGFβ2, TGFβ3, studied for cancer and focal segmental glomerulosclerosis.Pureza:> 95% - > 95%Forma y color:LiquidPeso molecular:144.4 kDaAxltide
CAS:Axltide mimics mouse Insulin receptor substrate 1, amino acids 979-989 with sequence KKSRGDYMTMQIG.Fórmula:C63H107N19O20S2Pureza:98%Forma y color:SolidPeso molecular:1514.77YAP-TEAD-IN-1 acetate
YAP-TEAD-IN-1 acetate is an effective and competitive inhibitor of YAP–TEAD interaction with an IC50 of 25 nM.Fórmula:C95H148ClN23O23S2Pureza:98.11% - 99.57%Forma y color:SoildPeso molecular:2079.92HAT-SIL-TG-1&AT
HAT-SIL-TG-1&AT: a hypoxia-activated JAK inhibitor that curbs HEL cell growth & STAT3/5 phosphorylation in tumors.Fórmula:C60H69N17O11SForma y color:SolidPeso molecular:1236.36STX-0119
CAS:STX-0119 is a selective, orally active STAT3 dimerization inhibitor. STX-0119 inhibits STAT3 transcription with an IC50 of 74 μM.
Fórmula:C22H14N4O3Pureza:99.61%Forma y color:SolidPeso molecular:382.37PSEN1-IN-2
PSEN1-IN-2 (Compound 13K) is a potent inhibitor of both PSEN1-APH1A and PSEN1-APH1B complexes, exhibiting IC50 values of 6.9 nM and 2.4 nM, respectively.Fórmula:C20H18ClFN2O3SForma y color:SolidPeso molecular:420.88Disitertide acetate
Disitertide acetate: a TGF-β1 and PI3K blocker, promotes apoptosis; inhibits receptor interaction.Fórmula:C70H113N17O24S2Pureza:95.11%Forma y color:SoildPeso molecular:1640.88PSEN1-IN-1
PSEN1-IN-1 (Compound (+)-13b) functions as an inhibitor of PSEN1, displaying potent inhibition of the PSEN1-APH1A and PSEN1-APH1B complexes with respective IC50Fórmula:C20H19ClF3NO3SForma y color:SolidPeso molecular:445.88PROTAC TYK2 degradation agent1
CAS:PROTAC TYK2 Agent1 selectively degrades TYK2, with a 14 nM DC50, for autoimmune research.Fórmula:C55H69N13O7SPureza:98%Forma y color:SolidPeso molecular:1056.28SAHM1
CAS:Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.Fórmula:C94H162N36O23SPureza:98%Forma y color:SolidPeso molecular:2196.58Tyrosine Kinase Inhibitor Library
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase relatedForma y color:Odour SolidRef: TM-L2200
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarKinase Inhibitor Library
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Forma y color:Odour SolidRef: TM-L1600
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarPovorcitinib phosphate
CAS:Povorcitinib phosphate is a selective JAK1 inhibitor and can be used in studies about the treatment of cutaneous lupus erythematosus and Lichen planus.Fórmula:C23H25F5N7O5PPureza:99.57%Forma y color:SolidPeso molecular:605.45Ref: TM-T39113L
1mg46,00€5mg96,00€1mL*10mM (DMSO)128,00€10mg145,00€25mg236,00€50mg339,00€100mg460,00€200mg622,00€SJ988497
CAS:SJ988497: PROTAC JAK2 degrader, inhibits CRLF2r cell growth, degrades GSPT1, combines Ruxolitinib, linker, Pomalidomide; researched for ALL.Fórmula:C36H36N10O5Forma y color:SolidPeso molecular:688.74Super-TDU (1-31) (TFA)
Super-TDU (1-31) TFA, a peptide, inhibits YAP-TEAD; it has strong anti-tumor effects in gastric cancer models.Fórmula:C141H218N40O48·C2HF3O2Forma y color:SolidPeso molecular:3355.5SJ10542
CAS:SJ10542: potent JAK2/3-targeting PG-PROTAC; DC50s: JAK2 - 14 nM, JAK3 - 11 nM, JAK2-fusion ALL - 24 nM; CRBN recruiter.Fórmula:C41H46N12O5SForma y color:SolidPeso molecular:818.95γ-Secretase modulator 10
CAS:γ-Secretase modulator 10 is a novel γ-secretase modulator.Fórmula:C25H23F3N4O2Forma y color:SolidPeso molecular:468.48WDR5 ligand 2
CAS:WDR5ligand 2 is a ligand for WDR5 and can be utilized in the synthesis of PROTAC WDR5degrader 1.Fórmula:C29H31F3N4O4Forma y color:SolidPeso molecular:556.576Epigenetics Compound Library
Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for newForma y color:Odour SolidRef: TM-L1200
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarHC-258
CAS:HC-258 is a direct TEAD inhibitor covalent Cys380, and reduces the transcriptional levels and inhibits the migration of CTGF, CYR61, AXL and NF2 MDA-MB-231.Fórmula:C20H24N2O2Forma y color:SolidPeso molecular:324.42
