Receptor del factor de crecimiento de fibroblastos (FGFR)
Los inhibidores de FGFR (receptores del factor de crecimiento de fibroblastos) son terapias dirigidas que bloquean la actividad de los FGFR, los cuales están involucrados en la proliferación celular, diferenciación y angiogénesis. La señalización de FGFR contribuye a la formación de nuevos vasos sanguíneos en los tumores, promoviendo su crecimiento y supervivencia. Inhibir FGFR puede, por lo tanto, reducir la angiogénesis y la progresión tumoral. En CymitQuimica, ofrecemos una gama de inhibidores de FGFR de alta calidad para apoyar su investigación en cáncer, biología del desarrollo y angiogénesis.
Se han encontrado 185 productos para "Receptor del factor de crecimiento de fibroblastos (FGFR)".
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Regorafenib
CAS:Fórmula:C21H15ClF4N4O3Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:482.82PD-161570
CAS:Fórmula:C26H35Cl2N7OPureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:532.51Methyl 1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylate
CAS:Fórmula:C21H19NO5Pureza:>95.0%(HPLC)(qNMR)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:365.39Nintedanib
CAS:Fórmula:C31H33N5O4Pureza:>95.0%(HPLC)(T)Forma y color:White to Yellow to Yellow green powder to crystalPeso molecular:539.64PD 173074
CAS:Fórmula:C28H41N7O3Pureza:>95.0%(HPLC)Forma y color:White to Yellow to Orange powder to crystalPeso molecular:523.682-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
CAS:Fórmula:C21H15ClF4N4O3Pureza:98%Forma y color:SolidPeso molecular:482.8154Ref: IN-DA00ICN3
100gA consultar10mg28,00€50mg43,00€100mg52,00€250mg65,00€500mg94,00€1g124,00€5g283,00€10g583,00€50g615,00€2,5-Dihydroxybenzoic acid
CAS:2,5-Dihydroxybenzoic acid (Gentisic acid) is an active metabolite of salicylic acid degradation with a broad spectrum of biological activity.Fórmula:C7H6O4Pureza:99.63%Forma y color:White SolidPeso molecular:154.1201Pemigatinib
CAS:Pemigatinib (INCB054828) is an orally active, selective inhibitor of FGFR(IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively).Fórmula:C24H27F2N5O4Pureza:99.57% - 99.95%Forma y color:White SolidPeso molecular:487.5Lenvatinib
CAS:Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Fórmula:C21H19ClN4O4Pureza:98.46% - 99.96%Forma y color:White SolidPeso molecular:426.85Lucitanib
CAS:Lucitanib (E-3810) is a VEGFR/FGFR inhibitor targeting VEGFR1-3 and FGFR1-2 with IC50s 7-82.5 nM.Fórmula:C26H25N3O4Pureza:97.33%Forma y color:SolidPeso molecular:443.49Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD
CAS:Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist.Fórmula:C26H32N4O8Pureza:99.83% - >99.99%Forma y color:SolidPeso molecular:528.55Formononetin
CAS:Formononetin (Flavosil) is an O-methylated isoflavone and a phytoestrogen from the root of Astragalus membranaceus.Fórmula:C16H12O4Pureza:97.39% - 99.94%Forma y color:SolidPeso molecular:268.2641Gunagratinib
CAS:Gunagratinib (ICP-192) is a pan-FGFR inhibitor, useful in research on FGFR-related diseases.Fórmula:C22H25N5O4Pureza:99.68%Forma y color:SolidPeso molecular:423.47Ref: TM-T39682
1mg69,00€5mg147,00€1mL*10mM (DMSO)164,00€10mg224,00€25mg358,00€50mg512,00€100mg707,00€Ferulic Acid
CAS:Ferulic Acid (Coniferic acid) is a highly abundant phenolic phytochemical and a organic compound found in the Ferula assafoetida L. or Ligusticum chuanxiong.Fórmula:C10H10O4Pureza:99.72%Forma y color:SolidPeso molecular:194.184FGFR1/DDR2 inhibitor 1
CAS:FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108Fórmula:C28H22F3N5OPureza:99.43%Forma y color:White SolidPeso molecular:501.5Ref: TM-T11279
1mg96,00€5mg205,00€1mL*10mM (DMSO)227,00€10mg334,00€25mg550,00€50mg760,00€100mg1.108,00€Amlexanox
CAS:Amlexanox (AA673) treats ulcers by blocking leukotrienes, histamine, reducing inflammation, pain, and healing time.Fórmula:C16H14N2O4Pureza:99.67% - ≥95%Forma y color:SolidPeso molecular:298.29Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Fórmula:C21H23N7O2SPureza:98.78% - 99.85%Forma y color:SolidPeso molecular:437.518LC-MB12
CAS:LC-MB12 is a PROTAC FGFR2 compound that degrades FGFR2 and can be used to study gastric cancer.Fórmula:C43H44Cl2N10O8Pureza:99.16%Forma y color:SolidPeso molecular:899.78FGFR1/VEGFR2-IN-1
FGFR1/VEGFR2-IN-1 (compound 2b) is an inhibitor of both FGFR1 and VEGFR2, applicable in cancer research [1].Fórmula:C26H27N4O6PPureza:98%Forma y color:SolidPeso molecular:522.49
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