c-Fms
Los inhibidores de c-Fms se dirigen al receptor del factor estimulante de colonias-1 (c-Fms), una tirosina quinasa involucrada en la regulación de los macrófagos y otras células inmunitarias. La señalización de c-Fms juega un papel en la proliferación, diferenciación y supervivencia de estas células. La desregulación de c-Fms está asociada con enfermedades como el cáncer, condiciones inflamatorias y osteoporosis. En CymitQuimica, ofrecemos inhibidores de c-Fms para apoyar su investigación en inmunología, oncología y enfermedades inflamatorias.
Se han encontrado 117 productos para "c-Fms".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
AZD7507
CAS:AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.Fórmula:C23H27FN6O3Pureza:99.55% - 99.78%Forma y color:SolidPeso molecular:454.5Ref: TM-T14380
1mg50,00€5mg110,00€1mL*10mM (DMSO)127,00€10mg161,00€25mg289,00€50mg419,00€100mg583,00€200mg787,00€GW2580
CAS:GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.Fórmula:C20H22N4O3Pureza:99.48% - >99.99%Forma y color:Yellow SolidPeso molecular:366.41Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Fórmula:C24H24N4O5SPureza:98.97% - 99.88%Forma y color:SolidPeso molecular:480.54Ref: TM-T4315
1mg44,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg145,00€25mg268,00€50mg439,00€100mg700,00€200mg954,00€PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Fórmula:C22H25N7O2Pureza:97.58% - 99.94%Forma y color:Yellow SolidPeso molecular:419.48PLX5622
CAS:PLX5622 is a selective, orally active and blood-brain barrier permeable CSF1R inhibitor. PLX5622 induces elimination of microglia. Cost effective and quality assured.Fórmula:C21H19F2N5OPureza:98% - 99.97%Forma y color:SolidPeso molecular:395.41Ref: TM-T7100
1mg43,00€1mL*10mM (DMSO)77,00€5mg81,00€10mg118,00€25mg230,00€50mg385,00€100mg502,00€200mg710,00€29g11.700,00€GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Fórmula:C21H23N7O2S·HClPureza:99.87%Forma y color:SolidPeso molecular:473.98Edicotinib HCl
CAS:Edicotinib (JNJ-40346527), an oral CSF1R inhibitor, may block FMS autophosphorylation, impeding tumor cell growth.Fórmula:C27H36ClN5O2Forma y color:SolidPeso molecular:498.07PRN1371
CAS:PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).Fórmula:C26H30Cl2N6O4Pureza:98.65%Forma y color:SolidPeso molecular:561.46Ref: TM-TQ0015
1mg77,00€2mg100,00€5mg166,00€1mL*10mM (DMSO)200,00€10mg289,00€25mg492,00€50mg710,00€100mg973,00€Seralutinib
CAS:Seralutinib (GB002) is an inhibitor of inhaled PDGFRα and PDGFRβ. It is used in the study for pulmonary arterial hypertension.Fórmula:C27H27N5O3Pureza:99.09%Forma y color:SolidPeso molecular:469.54Ref: TM-T8900
1mg47,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)92,00€10mg137,00€25mg236,00€50mg313,00€100mg497,00€Nampt-IN-1
CAS:Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.Fórmula:C20H25N3O5SPureza:99.28% - 99.4%Forma y color:SolidPeso molecular:419.49Ref: TM-T4376
1mg37,00€2mg49,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg130,00€25mg245,00€50mg409,00€100mg605,00€Vimseltinib
CAS:Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).Fórmula:C23H25N7O2Pureza:99.05% - 99.57%Forma y color:SolidPeso molecular:431.49Ref: TM-T10652
1mg87,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg295,00€25mg505,00€50mg690,00€100mg888,00€Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFórmula:C21H18FN5OPureza:98% - 98.24%Forma y color:White SolidPeso molecular:375.4Ref: TM-T2514
5mg48,00€1mL*10mM (DMSO)50,00€10mg80,00€25mg119,00€50mg178,00€100mg259,00€200mg477,00€500mg772,00€Sotuletinib
CAS:Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.Fórmula:C20H22N4O3SPureza:97.43% - 99.82%Forma y color:Yellow SolidPeso molecular:398.48Ref: TM-T6119
1mg34,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg105,00€25mg163,00€50mg205,00€100mg358,00€500mg822,00€Pexidartinib
CAS:Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFórmula:C20H15ClF3N5Pureza:98.34% - 99.45%Forma y color:White SolidPeso molecular:417.81Ref: TM-T2115
1kgA consultar5mg46,00€1mL*10mM (DMSO)49,00€10mg58,00€25mg90,00€50mg114,00€100mg145,00€200mg192,00€500mg333,00€7g2.815,00€OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Fórmula:C22H16F3N3O2SPureza:99.67%Forma y color:White SolidPeso molecular:443.44Anumigilimab
CAS:Anumigilimab (CSL-324) is a fully human therapeutic anti-G-CSFR antibody with potential anti-tumor activity for the study of inflammation.Pureza:95.75% (SEC-HPLC) - 98.43% (SEC-HPLC)Forma y color:Transparent LiquidPeso molecular:143.86 kDaCerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Fórmula:C20H28ClN7O3SPureza:99.85%Forma y color:SolidPeso molecular:482Lenzilumab
CAS:Lenzilumab (KB 003) is a humanized GM-CSF neutralizing antibody for the study of COVID-19.Pureza:98.9% (SDS-PAGE); 98.5% (SEC-HPLC) - 98.9% (SDS-PAGE); 98.5% (SEC-HPLC)Forma y color:Transparent LiquidPeso molecular:146.81 kDaPLX5622 in AIN-76A Diet (1200 ppm)
Application: Used in rodent models such as mice to achieve stable administration of PLX5622 through continuous feeding. This product is currently available for purchase only within the United States.Forma y color:Green SolidPLX3397 in AIN-76A Diet (290 ppm)
Application: Used in rodent models, such as mice, to achieve stable administration of PLX3397 through continuous feeding. This product is currently available for purchase only within the United States.
