c-Fms
Los inhibidores de c-Fms se dirigen al receptor del factor estimulante de colonias-1 (c-Fms), una tirosina quinasa involucrada en la regulación de los macrófagos y otras células inmunitarias. La señalización de c-Fms juega un papel en la proliferación, diferenciación y supervivencia de estas células. La desregulación de c-Fms está asociada con enfermedades como el cáncer, condiciones inflamatorias y osteoporosis. En CymitQuimica, ofrecemos inhibidores de c-Fms para apoyar su investigación en inmunología, oncología y enfermedades inflamatorias.
Se han encontrado 117 productos para "c-Fms".
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Namilumab
CAS:Namilumab (AMG203) is a humanised IgG1 monoclonal antibody that neutralises GM-CSF. rheumatoid arthritis and active axial spondyloarthritis.Pureza:95%Forma y color:Transparent LiquidPeso molecular:~150 kDaCabiralizumab
CAS:Cabiralizumab is an anti-CSF1R monoclonal antibody that enhances T cell infiltration, inhibits osteoclasts, and is used in RA and immune-oncology research.Pureza:98.2% (SDS-PAGE); 98.1% (SEC-HPLC) - 98.2% (SDS-PAGE); 98.1% (SEC-HPLC)Forma y color:Transparent LiquidPeso molecular:146.30 kDaTrabikibart
CAS:Trabikibart (CSL311) is a human βc-specific antibody inhibiting IL-3, GM-CSF and IL-5, regulating eosinophil survival in chronic inflammatory disease research.Pureza:95% - 95.6% (SDS-PAGE); 99.3% (SEC-HPLC)Forma y color:Transparent LiquidPeso molecular:144.64 kDaAnti-Mouse GM-CSF Antibody (MP1-22E9)
Anti-Mouse GM-CSF Antibody (MP1-22E9) neutralizes GM-CSF, used in cancer, infection and inflammation research.Pureza:95% - 99.9% (SDS-PAGE); 99.8% (SEC-HPLC)Forma y color:Transparent LiquidPeso molecular:142.44 kDaAnti-Human GM-CSF Antibody (BVD2-21C11)
Anti-Human GM-CSF Antibody (BVD2-21C11) targets human GM-CSF for life science research.Pureza:95% - 98.6% (SDS-PAGE); 97.0% (SEC-HPLC)Peso molecular:143.10 kDaCSF1R-IN-19
CAS:CSF1R-IN-19 is a robust inhibitor of CSF1R that influences the exchange of inflammatory factors between TAMs and glioma cells. It holds potential for cancer research [1].Fórmula:C20H27N7OForma y color:SolidPeso molecular:381.47CSF1R-IN-14
CAS:CSF1R-IN-14, an isoindolinone derivative, powerfully inhibits CSF1R, with potential in cancer research. See WO2019134662A1, compound 1.Fórmula:C23H22F3N5OForma y color:SolidPeso molecular:441.45CSF1R-IN-9
CAS:CSF1R-IN-9 (Compound 46) is a CSF-1R inhibitor (IC50: 0.028 μM).Fórmula:C26H26N4O2Forma y color:SolidPeso molecular:426.51CSF1R-IN-7
CAS:CSF1R-IN-7 is a highly selective CSF-1R inhibitor with good brain penetration for treatment of diseases associated with microglia-mediated neuroinflammation.Fórmula:C22H22N6O3Pureza:99.41% - 99.93%Forma y color:SolidPeso molecular:418.45CSF1R-IN-12
CAS:CSF1R-IN-12 is a CSF1R inhibitor for cancer-related disease research.Fórmula:C21H17F3N4OForma y color:Brown SolidPeso molecular:398.38ABD-295
CAS:ABD-295, a biphenylsulfide derivative, inhibits osteoclasts and prevents bone loss in vitro and in vivo.Fórmula:C17H19F2NO3SPureza:98%Forma y color:SolidPeso molecular:355.4AMG-820
AMG-820 is a human antibody targeting CSF-1R, inhibiting the binding of ligands CSF1 and IL34, and preventing subsequent ligand-induced receptor activation. For AMG-820's isotype control, refer to [Human IgG2 kappa, Isotype Control].Forma y color:Odour LiquidLeustroducsin C
CAS:Leustroducsin C is an inducer of colony-stimulating factors CSF extracted from Streptomyces platensis SANK 60191.Fórmula:C34H56NO10PForma y color:SolidPeso molecular:669.78CSF1R-IN-10
CAS:CSF1R-IN-10 (Compound 48) is a CSF-1R inhibitor (IC50: 0.005 μM).Fórmula:C25H22N4O3Forma y color:SolidPeso molecular:426.47CSF1R-IN-8
CAS:CSF1R-IN-8 (Compound 22) is a CSF-1R inhibitor (IC50: 0.012 μM).Fórmula:C24H22N4O4Forma y color:SolidPeso molecular:430.46PD-360324
PD-360324 is a human monoclonal antibody (mAb) that targets CSF1/M-CSF. It can be utilized in research related to skin lupus, pulmonary sarcoidosis, and rheumatoid arthritis.Forma y color:Odour LiquidCSF1R-IN-13
CAS:CSF1R-IN-13: potent cancer research CSF1R inhibitor impacting cell growth regulation.Fórmula:C21H20N4O3Forma y color:SolidPeso molecular:376.41Sotuletinib dihydrochloride
CAS:Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable inhibitor specifically targeting CSF1-R with an IC50 of 1 nM.Fórmula:C20H24Cl2N4O3SPureza:98%Forma y color:SolidPeso molecular:471.4IACS-9439
CAS:IACS-9439 is a potent, selective, and orally active inhibitor of CSF1R, exhibiting a K(i) of 1 nM.Fórmula:C23H26ClN7O3SPureza:98%Forma y color:SolidPeso molecular:516.02c-Fms-IN-1
CAS:c-Fms-IN-1 is an inhibitor of c-FMS kinase (IC50 = 0.8 nM).Fórmula:C22H27N5O2Pureza:99.94%Forma y color:Yellow SolidPeso molecular:393.48
