Src
Los inhibidores de Src son compuestos que se dirigen a las quinasas de la familia Src, que están involucradas en diversos procesos celulares, como el crecimiento, la diferenciación y la angiogénesis. Las quinasas Src desempeñan un papel crucial en las vías de señalización que promueven la formación de nuevos vasos sanguíneos en los tumores. Inhibir Src puede interrumpir estas vías, reduciendo así la angiogénesis y el crecimiento tumoral. Los inhibidores de Src se utilizan ampliamente en la investigación del cáncer y en el desarrollo terapéutico. En CymitQuimica, ofrecemos una selección completa de inhibidores de Src de alta calidad para apoyar su investigación en oncología, señalización celular y angiogénesis.
Se han encontrado 78 productos de "Src"
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β-Hydroxyisovalerylshikonin
CAS:<p>Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor</p>Fórmula:C21H24O7Pureza:98.16%Forma y color:SolidPeso molecular:388.41Pyridostatin TFA
CAS:<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Forma y color:SolidPeso molecular:938.71Pyridostatin
CAS:<p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>Fórmula:C31H32N8O5Pureza:98%Forma y color:SolidPeso molecular:596.64AD80
CAS:<p>AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.</p>Fórmula:C22H19F4N7OPureza:99.49% - 99.75%Forma y color:SolidPeso molecular:473.43Tolimidone
CAS:<p>Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.</p>Fórmula:C11H10N2O2Pureza:99.85% - 99.85%Forma y color:SolidPeso molecular:202.21eCF506
CAS:<p>eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)</p>Fórmula:C26H38N8O3Pureza:97.85% - 98.16%Forma y color:SolidPeso molecular:510.63Rebastinib
CAS:<p>DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,</p>Fórmula:C30H28FN7O3Pureza:99.53% - 99.79%Forma y color:SolidPeso molecular:553.59UM-164
CAS:<p>UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.</p>Fórmula:C30H31F3N8O3SPureza:98.72% - 99.52%Forma y color:SolidPeso molecular:640.68Saracatinib
CAS:<p>Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.</p>Fórmula:C27H32ClN5O5Pureza:98% - 99.63%Forma y color:SolidPeso molecular:542.031-Naphthyl PP1
CAS:<p>1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)</p>Fórmula:C19H19N5Pureza:99.85%Forma y color:White Cyrstalline SolidPeso molecular:317.39Src Inhibitor 1
CAS:<p>Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor.</p>Fórmula:C22H19N3O3Pureza:99.68% - >99.99%Forma y color:SolidPeso molecular:373.4Ponatinib
CAS:<p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>Fórmula:C29H27F3N6OPureza:98% - 99.60%Forma y color:SolidPeso molecular:532.56PI3K-IN-1
CAS:<p>PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.</p>Fórmula:C31H29N5O6SPureza:97.03% - 98%Forma y color:SolidPeso molecular:599.66MNS
CAS:<p>MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.</p>Fórmula:C9H7NO4Pureza:98.53%Forma y color:Yellow PowderPeso molecular:193.16lavendustin C
CAS:<p>lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.</p>Fórmula:C14H13NO5Pureza:98.06%Forma y color:Yellow To Tan PowderPeso molecular:275.26PP1
CAS:<p>PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.</p>Fórmula:C16H19N5Pureza:99% - 99.88%Forma y color:Off-White To Grey SolidPeso molecular:281.36WH-4-023
CAS:<p>WH-4-023 (Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor. It also potently inhibits SIK.</p>Fórmula:C32H36N6O4Pureza:98% - 99.75%Forma y color:SolidPeso molecular:568.671-NM-PP1
CAS:<p>1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.</p>Fórmula:C20H21N5Pureza:98% - 98.93%Forma y color:White Cyrstalline SolidPeso molecular:331.41Masitinib mesylate
CAS:<p>Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;</p>Fórmula:C29H34N6O4S2Pureza:97.67% - 98.44%Forma y color:SolidPeso molecular:594.75KX1-004
CAS:<p>KX1-004, a potential protective drug for NIHL, is an effective small molecule inhibitor of Src-PTK.</p>Fórmula:C16H13FN2O2Pureza:99.39% - ≥95%Forma y color:SolidPeso molecular:284.29
