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Autofagia

Autofagia

Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.

Se han encontrado 1428 productos de "Autofagia"

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  • LYN-1604

    CAS:
    <p>LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>
    Fórmula:C33H43Cl2N3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:584.62
  • SR9009

    CAS:
    <p>SR9009, a REV-ERB agonist, modulates genes and circadian rhythms, reducing fat mass and improving metabolism in obese mice.</p>
    Fórmula:C20H24ClN3O4S
    Pureza:99.94% - >99.99%
    Forma y color:Solid
    Peso molecular:437.94
  • NL-1

    CAS:
    <p>NL-1 is a mitoNEET inhibitor with antileukemic effect.</p>
    Fórmula:C18H25NO3S
    Pureza:98.64%
    Forma y color:Solid
    Peso molecular:335.46
  • JH-II-127

    CAS:
    <p>JH-II-127 is an oral LRRK2 inhibitor with IC50s: 6.6 nM (WT), 2.2 nM (G2019S), 47.7 nM (A2016T).</p>
    Fórmula:C19H21ClN6O3
    Pureza:98.32%
    Forma y color:Solid
    Peso molecular:416.86
  • Kaempferol

    CAS:
    <p>Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.</p>
    Fórmula:C15H10O6
    Pureza:98% - 99.41%
    Forma y color:Yellow Needles From Alcohol And Water Solid
    Peso molecular:286.24
  • Ruxolitinib

    CAS:
    <p>Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.</p>
    Fórmula:C17H18N6
    Pureza:99.4% - >99.99%
    Forma y color:Solid
    Peso molecular:306.36
  • DPN

    CAS:
    <p>DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .</p>
    Fórmula:C15H13NO2
    Pureza:99.01%
    Forma y color:Off-White Solid
    Peso molecular:239.27
  • Silibinin

    CAS:
    <p>Silibinin, main component in milk thistle, offers liver protection and shows anti-cancer potential in various human cells.</p>
    Fórmula:C25H22O10
    Pureza:97.98% - 98.37%
    Forma y color:Solid
    Peso molecular:482.44
  • Nutlin-3a

    CAS:
    <p>Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.</p>
    Fórmula:C30H30Cl2N4O4
    Pureza:95.62% - 99.71%
    Forma y color:Solid
    Peso molecular:581.49
  • FIPI

    CAS:
    <p>FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.</p>
    Fórmula:C23H24FN5O2
    Pureza:97.21% - 98.68%
    Forma y color:Solid
    Peso molecular:421.47
  • Quercitrin

    CAS:
    <p>Quercitrin (3-rhamnosyl quercetin) is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities.</p>
    Fórmula:C21H20O11
    Pureza:98.89% - 99.66%
    Forma y color:Yellow Crystals From Dil Methanol Or Ethanol Solid
    Peso molecular:448.38
  • Quisinostat dihydrochloride

    CAS:
    <p>Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性,高效的 pan-HDAC 抑制剂,具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。</p>
    Fórmula:C21H28Cl2N6O2
    Pureza:97.13%
    Forma y color:Solid
    Peso molecular:467.39
  • Tozasertib

    CAS:
    <p>Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).</p>
    Fórmula:C23H28N8OS
    Pureza:99.99%
    Forma y color:Solid
    Peso molecular:464.59
  • Regorafenib Hydrochloride

    CAS:
    <p>Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.</p>
    Fórmula:C21H16Cl2F4N4O3
    Pureza:99.56%
    Forma y color:Solid
    Peso molecular:519.28
  • 3-Bromopyruvic acid

    CAS:
    <p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>
    Fórmula:C3H3BrO3
    Pureza:95% - 99.644%
    Forma y color:White To Pale Yellow Crystalline Powder
    Peso molecular:166.96
  • Aloe emodin

    CAS:
    <p>Aloe emodin (Rhabarberone) is an interferon-inducing agent, for JEV (IC50=1 μg/mL) and EV71(IC50=0.33 μg/mL ).</p>
    Fórmula:C15H10O5
    Pureza:97.00%
    Forma y color:Orange Solid
    Peso molecular:270.24
  • Fangchinoline

    CAS:
    <p>Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.</p>
    Fórmula:C37H40N2O6
    Pureza:99.86% - >99.99%
    Forma y color:Solid
    Peso molecular:608.72
  • AZD 6482

    CAS:
    <p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values ​​of 0.69nM and 10nM.Cost-effective and quality-assured.</p>
    Fórmula:C22H24N4O4
    Pureza:99.79% - 99.95%
    Forma y color:Solid
    Peso molecular:408.45
  • Dioscin

    CAS:
    <p>Dioscin (Collettiside III) is a saponin with antitumor activities.</p>
    Fórmula:C45H72O16
    Pureza:99.85% - 99.87%
    Forma y color:Solid
    Peso molecular:869.04
  • GLPG1837

    CAS:
    <p>GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.</p>
    Fórmula:C16H20N4O3S
    Pureza:99.64% - 99.91%
    Forma y color:Solid
    Peso molecular:348.42
  • GSK343

    CAS:
    <p>GSK343, a specific and effective EZH2 inhibitor (IC50=4 nM), exhibits 60 fold specificity activity against EZH1, and &gt;1000 fold specificity activity against</p>
    Fórmula:C31H39N7O2
    Pureza:98% - 99.9%
    Forma y color:Solid
    Peso molecular:541.69
  • Neflamapimod

    CAS:
    <p>Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.</p>
    Fórmula:C19H9Cl2F2N3OS
    Pureza:97.88% - 99.75%
    Forma y color:Solid
    Peso molecular:436.26
  • Turofexorate Isopropyl

    CAS:
    <p>Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM</p>
    Fórmula:C25H24F2N2O3
    Pureza:98.55% - 99.73%
    Forma y color:Solid
    Peso molecular:438.47
  • LYN-1604 dihydrochloride

    CAS:
    <p>LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>
    Fórmula:C33H45Cl4N3O2
    Pureza:98.95% - 99.92%
    Forma y color:Solid
    Peso molecular:657.54
  • Salvianolic acid B

    CAS:
    <p>Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia miltiorrhiza extract with antiplatelet aggregation and antithrombotic effects.</p>
    Fórmula:C36H30O16
    Pureza:99.75% - 99.86%
    Forma y color:Yellow Solid
    Peso molecular:718.61
  • SGI-1776

    CAS:
    <p>SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.</p>
    Fórmula:C20H22F3N5O
    Pureza:99.3% - >99.99%
    Forma y color:Solid
    Peso molecular:405.42
  • OSU-T315

    CAS:
    <p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>
    Fórmula:C30H30F3N5O
    Pureza:98.69%
    Forma y color:Solid
    Peso molecular:533.59
  • Milciclib

    CAS:
    <p>Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. In Phase 2 trials.</p>
    Fórmula:C25H32N8O
    Pureza:99.28%
    Forma y color:Solid
    Peso molecular:460.57
  • STF-62247

    CAS:
    <p>STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.</p>
    Fórmula:C15H13N3S
    Pureza:99.6% - 99.67%
    Forma y color:Solid
    Peso molecular:267.35
  • Fenretinide

    CAS:
    <p>Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.</p>
    Fórmula:C26H33NO2
    Pureza:98% - 99.68%
    Forma y color:Yellow Powder
    Peso molecular:391.55
  • CD437

    CAS:
    <p>CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.</p>
    Fórmula:C27H26O3
    Pureza:98.92% - 99.63%
    Forma y color:Solid
    Peso molecular:398.49
  • Ixazomib

    CAS:
    <p>Ixazomib (MLN2238) is a boron-based peptide proteasome inhibitor targeting β5 site (IC50: 3.4 nM), also affecting β1 and β2 sites.</p>
    Fórmula:C14H19BCl2N2O4
    Pureza:98% - 98.92%
    Forma y color:Solid
    Peso molecular:361.03
  • FERULIC ACID METHYL ESTER

    CAS:
    <p>FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.</p>
    Fórmula:C11H12O4
    Pureza:99.66% - 99.95%
    Forma y color:Solid
    Peso molecular:208.21
  • SBE13 Hydrochloride

    CAS:
    <p>SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.</p>
    Fórmula:C24H28Cl2N2O4
    Pureza:99.00% - ≥95%
    Forma y color:Solid
    Peso molecular:479.4
  • Oxyphenisatin acetate

    CAS:
    <p>Oxyphenisatin acetate inhibits the growth of the breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468.</p>
    Fórmula:C24H19NO5
    Pureza:98% - 99.35%
    Forma y color:Solid
    Peso molecular:401.41
  • LRRK2-IN-1

    CAS:
    <p>LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.</p>
    Fórmula:C31H38N8O3
    Pureza:98% - 98.82%
    Forma y color:Solid
    Peso molecular:570.69
  • Tenovin-6 Hydrochloride

    CAS:
    <p>Tenovin-6 HCl: Inhibits SIRT1 (21µM), SIRT2 (10µM), HDAC8; potent p53 activator.</p>
    Fórmula:C25H35ClN4O2S
    Pureza:99.36%
    Forma y color:Solid
    Peso molecular:491.09
  • Daphnetin

    CAS:
    <p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>
    Fórmula:C9H6O4
    Pureza:97.47% - 99.8%
    Forma y color:Solid
    Peso molecular:178.14
  • H-89 dihydrochloride

    CAS:
    <p>H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).</p>
    Fórmula:C20H20BrN3O2S·2HCl
    Pureza:98.22% - >99.99%
    Forma y color:Solid
    Peso molecular:519.28
  • PD98059

    CAS:
    <p>PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.</p>
    Fórmula:C16H13NO3
    Pureza:98.63% - >99.99%
    Forma y color:Yellow Solid
    Peso molecular:267.28
  • ML327

    CAS:
    <p>ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).</p>
    Fórmula:C19H18N4O4
    Pureza:98.47%
    Forma y color:Solid
    Peso molecular:366.37
  • YM-201636

    CAS:
    <p>YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.</p>
    Fórmula:C25H21N7O3
    Pureza:93.28% - 98.3%
    Forma y color:Solid
    Peso molecular:467.48
  • Sitagliptin phosphate

    CAS:
    <p>Sitagliptin phosphate (MK-0431 phosphate) is a dipeptidyl peptidase-4 (DPP4) inhibitor.</p>
    Fórmula:C16H18F6N5O5P
    Pureza:99.72% - 99.91%
    Forma y color:White Solid
    Peso molecular:505.31
  • Doramapimod

    CAS:
    Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.
    Fórmula:C31H37N5O3
    Pureza:97.14% - 98.80%
    Forma y color:Solid
    Peso molecular:527.66
  • KN-92 phosphate

    CAS:
    <p>KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93.</p>
    Fórmula:C24H28ClN2O7PS
    Pureza:99.86%
    Forma y color:Solid
    Peso molecular:554.98
  • Veliparib dihydrochloride

    CAS:
    <p>Veliparib dihydrochloride (ABT-888 dihydrochloride) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively.</p>
    Fórmula:C13H18Cl2N4O
    Pureza:98% - 99.81%
    Forma y color:Solid
    Peso molecular:317.21
  • Wortmannin

    CAS:
    <p>Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible.</p>
    Fórmula:C23H24O8
    Pureza:95.84% - 99.76%
    Forma y color:White Solid
    Peso molecular:428.43
  • Ambroxol hydrochloride

    CAS:
    <p>Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract.</p>
    Fórmula:C13H18Br2N2O·HCl
    Pureza:99.70%
    Forma y color:White To Yellowish Crystalline Powder
    Peso molecular:414.56
  • CFTR corrector 2

    CAS:
    <p>CFTR corrector 2 (FDL169) is a novel and potent CFTR corrector for treating cystic fibrosis (CF) patients who carry the F508del mutation.</p>
    Fórmula:C27H23FN4O4
    Pureza:99.66%
    Forma y color:Solid
    Peso molecular:486.49
  • ZLN005

    CAS:
    <p>ZLN005 is an effective and tissue-specific transcriptional activator of PGC-1α.</p>
    Fórmula:C17H18N2
    Pureza:98.59% - >99.99%
    Forma y color:Solid
    Peso molecular:250.34
  • TWS119

    CAS:
    <p>TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiation</p>
    Fórmula:C18H14N4O2
    Pureza:98.14% - 99.63%
    Forma y color:Solid
    Peso molecular:318.33
  • Rutin hydrate

    CAS:
    <p>Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.</p>
    Fórmula:C27H32O17
    Pureza:97.23%
    Forma y color:Solid
    Peso molecular:628.53
  • Crizotinib hydrochloride

    CAS:
    <p>Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)</p>
    Fórmula:C21H23Cl3FN5O
    Pureza:98.73% - 98.87%
    Forma y color:Solid
    Peso molecular:486.8
  • Danusertib

    CAS:
    <p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>
    Fórmula:C26H30N6O3
    Pureza:97.88% - 98.79%
    Forma y color:White Powder
    Peso molecular:474.55
  • 3-Methyladenine

    CAS:
    <p>3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM).</p>
    Fórmula:C6H7N5
    Pureza:98.02% - 99.65%
    Forma y color:Solid
    Peso molecular:149.15
  • WYC-209

    CAS:
    <p>WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).</p>
    Fórmula:C20H20N2O3S
    Pureza:99.77%
    Forma y color:Solid
    Peso molecular:368.45
  • Salirasib

    CAS:
    <p>Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.</p>
    Fórmula:C22H30O2S
    Pureza:99.45%
    Forma y color:Solid
    Peso molecular:358.54
  • MRT67307 HCl (1190378-57-4(free base))


    MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).
    Fórmula:C26H37ClN6O2
    Pureza:98.19%
    Forma y color:Solid
    Peso molecular:501.07
  • Afatinib Dimaleate

    CAS:
    <p>Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.</p>
    Fórmula:C32H33ClFN5O11
    Pureza:98.11% - 99.87%
    Forma y color:Solid
    Peso molecular:718.08
  • Liensinine diperchlorate

    CAS:
    <p>Liensinine Diperchlorate is an isoquinoline alkaloid extracted from the embryonic seeds of the sacred lotus.</p>
    Fórmula:C37H44Cl2N2O14
    Pureza:99.8% - ≥95%
    Forma y color:Solid
    Peso molecular:811.67
  • TA-02

    CAS:
    <p>TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.</p>
    Fórmula:C20H13F2N3
    Pureza:99.35% - 99.79%
    Forma y color:Solid
    Peso molecular:333.33
  • Sepantronium bromide

    CAS:
    <p>Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.</p>
    Fórmula:C20H19BrN4O3
    Pureza:99.68% - 99.85%
    Forma y color:Solid
    Peso molecular:443.26
  • LY294002

    CAS:
    <p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>
    Fórmula:C19H17NO3
    Pureza:98% - 99.96%
    Forma y color:Pale Yellow Solid
    Peso molecular:307.34
  • Bafilomycin A1

    CAS:
    <p>Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.</p>
    Fórmula:C35H58O9
    Pureza:95.87% - 99.36%
    Forma y color:Solid
    Peso molecular:622.83
  • PFI-1

    CAS:
    <p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>
    Fórmula:C16H17N3O4S
    Pureza:98.74% - 99.19%
    Forma y color:Solid
    Peso molecular:347.39
  • Belinostat

    CAS:
    <p>Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.</p>
    Fórmula:C15H14N2O4S
    Pureza:99.75% - >99.99%
    Forma y color:Solid
    Peso molecular:318.35
  • 3'-Hydroxypterostilbene

    CAS:
    <p>3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.</p>
    Fórmula:C16H16O4
    Pureza:98.25% - 99.19%
    Forma y color:Solid
    Peso molecular:272.3
  • BIIB021

    CAS:
    <p>BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).</p>
    Fórmula:C14H15ClN6O
    Pureza:98% - 99.82%
    Forma y color:Solid
    Peso molecular:318.76
  • Quisinostat

    CAS:
    <p>Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.</p>
    Fórmula:C21H26N6O2
    Pureza:96.01% - ≥98%
    Forma y color:Solid
    Peso molecular:394.47
  • Sapanisertib

    CAS:
    <p>Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.</p>
    Fórmula:C15H15N7O
    Pureza:99.19% - >99.99%
    Forma y color:Solid
    Peso molecular:309.33
  • Isodeoxyelephantopin

    CAS:
    <p>Isodeoxyelephantopin can inhibit the growth of various tumor cells.</p>
    Fórmula:C19H20O6
    Pureza:99.88%
    Forma y color:Solid
    Peso molecular:344.36
  • Veliparib

    CAS:
    <p>Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.</p>
    Fórmula:C13H16N4O
    Pureza:98.66% - 99%
    Forma y color:Solid
    Peso molecular:244.29
  • Pyriproxyfen

    CAS:
    <p>Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.</p>
    Fórmula:C20H19NO3
    Pureza:99.83%
    Forma y color:Solid Compact
    Peso molecular:321.37
  • Flavopiridol hydrochloride

    CAS:
    <p>Flavopiridol hydrochloride (MDL 107826A), an inhibitor of cyclin-dependent kinase, is a synthetic N-methylpiperidinyl chlorophenyl flavone compound.</p>
    Fórmula:C21H21Cl2NO5
    Pureza:98.87% - 99.88%
    Forma y color:Solid
    Peso molecular:438.3
  • Orthanilamide

    CAS:
    <p>Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.</p>
    Fórmula:C6H8N2O2S
    Pureza:99.72% - 99.96%
    Forma y color:White To Pale Cream Crystalline Powder Or Crystals
    Peso molecular:172.2
  • AGN 193109

    CAS:
    <p>AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).</p>
    Fórmula:C28H24O2
    Pureza:99.87% - 99.89%
    Forma y color:Solid
    Peso molecular:392.49
  • MPP+ iodide

    CAS:
    <p>MPP+ iodide, a neurotoxin byproduct, mimics Parkinson's by killing substantia nigra neurons and affecting neuron transporters, inducing cell death.</p>
    Fórmula:C12H12IN
    Pureza:99.49% - 99.96%
    Forma y color:Solid
    Peso molecular:297.13
  • Genistein

    CAS:
    <p>Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.</p>
    Fórmula:C15H10O5
    Pureza:98.22% - 99.64%
    Forma y color:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether Solid
    Peso molecular:270.24
  • (1E,6E)-Bis(demethoxy)curcumin

    CAS:
    <p>(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.</p>
    Fórmula:C19H16O4
    Pureza:97.45%
    Forma y color:Solid
    Peso molecular:308.33
  • GSK2578215A

    CAS:
    <p>GSK2578215A is a potent and selective LRRK2 kinase inhibitor.</p>
    Fórmula:C24H18FN3O2
    Pureza:99.57% - 99.94%
    Forma y color:Solid
    Peso molecular:399.42
  • Imatinib

    CAS:
    <p>Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kit</p>
    Fórmula:C29H31N7O
    Pureza:99.42% - 99.94%
    Forma y color:Off White Powder
    Peso molecular:493.6
  • Demethoxycurcumin

    CAS:
    <p>Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.</p>
    Fórmula:C20H18O5
    Pureza:94.54% - 99.86%
    Forma y color:Solid
    Peso molecular:338.35
  • Aloperine

    CAS:
    <p>Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.</p>
    Fórmula:C15H24N2
    Pureza:98% - 99.88%
    Forma y color:Yellow Crystalline Powder
    Peso molecular:232.36
  • Arglabin

    CAS:
    <p>Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.</p>
    Fórmula:C15H18O3
    Pureza:98.97% - 99.62%
    Forma y color:Solid
    Peso molecular:246.3
  • Bilobalide

    CAS:
    <p>Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.</p>
    Fórmula:C15H18O8
    Pureza:98.81% - 99.92%
    Forma y color:White Solid
    Peso molecular:326.3
  • Apocynin

    CAS:
    <p>Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).</p>
    Fórmula:C9H10O3
    Pureza:99.71% - 99.98%
    Forma y color:Yellowish To Brown Powder
    Peso molecular:166.17
  • HA15

    CAS:
    <p>HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.</p>
    Fórmula:C23H22N4O3S2
    Pureza:99.77% - 99.86%
    Forma y color:Solid
    Peso molecular:466.58
  • Tomatidine

    CAS:
    <p>Tomatidine serves as an anti-inflammatory agent by inhibiting NF-κB and JNK signaling pathways.</p>
    Fórmula:C27H45NO2
    Pureza:99.94% - 99.98%
    Forma y color:Solid
    Peso molecular:415.65
  • ISRIB (trans-isomer)

    CAS:
    <p>ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.</p>
    Fórmula:C22H24Cl2N2O4
    Pureza:97.86% - 99.27%
    Forma y color:Solid
    Peso molecular:451.34
  • Binimetinib

    CAS:
    <p>Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity. Cost-effective and quality-assured.</p>
    Fórmula:C17H15BrF2N4O3
    Pureza:98.03% - >99.99%
    Forma y color:Solid
    Peso molecular:441.23
  • Reparixin

    CAS:
    <p>Reparixin inhibits CXCR1 (IC50=1 nM) strongly, CXCR2 weakly (IC50=100 nM), and it's a CXCL8 receptor blocker.</p>
    Fórmula:C14H21NO3S
    Pureza:98% - 99.89%
    Forma y color:Solid
    Peso molecular:283.39
  • GNE-7915

    CAS:
    <p>GNE-7915 is a highly potent, selective and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor.</p>
    Fórmula:C19H21F4N5O3
    Pureza:98% - ≥95%
    Forma y color:Solid
    Peso molecular:443.4
  • Daurisoline

    CAS:
    <p>Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.</p>
    Fórmula:C37H42N2O6
    Pureza:98% - 99.96%
    Forma y color:Light Yellow Powder
    Peso molecular:610.74
  • Bigelovin

    CAS:
    <p>Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.</p>
    Fórmula:C17H20O5
    Pureza:99.61% - 99.72%
    Forma y color:Solid
    Peso molecular:304.34
  • Britannin

    CAS:
    <p>Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.</p>
    Fórmula:C19H26O7
    Pureza:98% - 99.98%
    Forma y color:Solid
    Peso molecular:366.41
  • Verteporfin

    CAS:
    <p>Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.</p>
    Fórmula:C41H42N4O8
    Pureza:95.37% - 99.82%
    Forma y color:Dark Green To Black Solid
    Peso molecular:718.79
  • Ralimetinib dimesylate

    CAS:
    <p>Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.</p>
    Fórmula:C24H29FN6·2CH4O3S
    Pureza:98% - 99.38%
    Forma y color:Solid
    Peso molecular:612.74
  • Hydroxyprogesterone caproate

    CAS:
    <p>Hydroxyprogesterone caproate (Delalutin) is a synthetic progestin that activates progesterone receptors and inhibits ovulation.</p>
    Fórmula:C27H40O4
    Pureza:99.70%
    Forma y color:White Or Almost White Crystalline Power
    Peso molecular:428.60
  • Tizoxanide

    CAS:
    <p>Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.</p>
    Fórmula:C10H7N3O4S
    Pureza:98.89% - 99.28%
    Forma y color:Solid
    Peso molecular:265.25
  • Bardoxolone Methyl

    CAS:
    <p>Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-</p>
    Fórmula:C32H43NO4
    Pureza:97.81% - 99.09%
    Forma y color:Solid
    Peso molecular:505.69