Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1424 productos de "Autofagia"
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Hydroxyurea
CAS:<p>Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.</p>Fórmula:CH4N2O2Pureza:99.85% - 99.92%Forma y color:SolidPeso molecular:76.05Glibenclamide
CAS:<p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>Fórmula:C23H28ClN3O5SPureza:99.05% - 99.75%Forma y color:SolidPeso molecular:494.00Spironolactone
CAS:<p>Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.</p>Fórmula:C24H32O4SPureza:99.87%Forma y color:White PowderPeso molecular:416.57BIX 02565
CAS:<p>BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).</p>Fórmula:C26H30N6O2Pureza:97.44% - 99.7%Forma y color:SolidPeso molecular:458.56Erlotinib
CAS:<p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Fórmula:C22H23N3O4Pureza:98.19% - 99.98%Forma y color:White To Off-White PowderPeso molecular:393.44Lapatinib ditosylate monohydrate
CAS:<p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>Fórmula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPureza:98% - 99.41%Forma y color:Colourless To Light-Yellow CrystalPeso molecular:943.47Raloxifene hydrochloride
CAS:<p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>Fórmula:C28H28ClNO4SPureza:98% - 99.97%Forma y color:Light Yellow SolidPeso molecular:510.044Dexamethasone acetate
CAS:<p>Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.</p>Fórmula:C24H31FO6Pureza:99.22% - 99.65%Forma y color:White Or Almost White Crystalline PowderPeso molecular:434.50Oxaliplatin
CAS:<p>Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.</p>Fórmula:C8H14N2O4PtPureza:97% - 99.93%Forma y color:SolidPeso molecular:397.29Sunitinib Malate
CAS:<p>Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.</p>Fórmula:C26H33FN4O7Pureza:98% - 99.26%Forma y color:SolidPeso molecular:532.56Chenodeoxycholic acid
CAS:<p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>Fórmula:C24H40O4Pureza:99.70% - 99.93%Forma y color:White - Almost White Solid PowderPeso molecular:392.57Avermectin B1
CAS:<p>Avermectin B1 is served as anthelmintic and insecticide.</p>Fórmula:C48H72O14Pureza:mixture - mixtureForma y color:White PowderPeso molecular:873.09Reserpine
CAS:<p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>Fórmula:C33H40N2O9Pureza:98.85% - 99.81%Forma y color:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Peso molecular:608.68Dexamethasone
CAS:<p>Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.</p>Fórmula:C22H29FO5Pureza:98% - 99.91%Forma y color:Crystals From Ether (Ntp 1992)Peso molecular:392.46Thalidomide
CAS:<p>Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.</p>Fórmula:C13H10N2O4Pureza:98.88% - 99.88%Forma y color:White SolidPeso molecular:258.23Doxazosin mesylate
CAS:<p>Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.</p>Fórmula:C24H29N5O8SPureza:99.92%Forma y color:White To Off-White Crystalline PowderPeso molecular:547.58Fluvastatin sodium
CAS:<p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>Fórmula:C24H25FNNaO4Pureza:98.54% - 99.56%Forma y color:Light Yellow Solid PowderPeso molecular:433.45Pictilisib dimethanesulfonate
CAS:<p>Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and</p>Fórmula:C25H35N7O9S4Pureza:99.63%Forma y color:SolidPeso molecular:705.85Doxorubicin hydrochloride
CAS:<p>Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).</p>Fórmula:C27H29NO11·HClPureza:98% - 99.52%Forma y color:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecular:579.99Colistin sulfate
CAS:<p>Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.</p>Fórmula:C53H100N16O17SPureza:98%Forma y color:PowderPeso molecular:1253.51
