Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1427 productos de "Autofagia"
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Hesperadin
CAS:<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Fórmula:C29H32N4O3SPureza:98.04% - 99.44%Forma y color:SolidPeso molecular:516.65Metformin
CAS:<p>Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.</p>Fórmula:C4H11N5Pureza:99.77% - >99.99%Forma y color:SolidPeso molecular:129.16Indomethacin farnesil
CAS:<p>Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug.</p>Fórmula:C34H40ClNO4Pureza:97.29%Forma y color:SolidPeso molecular:562.14SB 202190
CAS:<p>SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.</p>Fórmula:C20H14FN3OPureza:98% - 99.84%Forma y color:Pale YellowPeso molecular:331.34CaMKII-IN-1
CAS:<p>CaMKII-IN-1 is a potent and highly selective inhibitor of CaMKII (IC50 = 63 nM).</p>Fórmula:C29H30ClN5O2SPureza:99.69%Forma y color:SolidPeso molecular:548.1Dihydromyricetin
CAS:<p>Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.</p>Fórmula:C15H12O8Pureza:96.68% - 98.229%Forma y color:SolidPeso molecular:320.25MHY1485
CAS:<p>MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, thereby inhibiting autophagy. Cost-effective and quality-assured.</p>Fórmula:C17H21N7O4Pureza:97.74% - >99.99%Forma y color:SolidPeso molecular:387.39(-)-Epicatechin gallate
CAS:<p>(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.</p>Fórmula:C22H18O10Pureza:99.16% - 99.93%Forma y color:SolidPeso molecular:442.371-Monomyristin
CAS:<p>1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial</p>Fórmula:C17H34O4Pureza:99.58%Forma y color:SolidPeso molecular:302.45Icariin
CAS:<p>Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.</p>Fórmula:C33H40O15Pureza:97.82% - 98.3%Forma y color:SolidPeso molecular:676.66Nocodazole
CAS:<p>Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.</p>Fórmula:C14H11N3O3SPureza:98% - 99.91%Forma y color:Physical Description White Powder (Ntp 1992)Peso molecular:301.32CFTR(inh)-172
CAS:<p>CFTR(inh)-172 (CFTR Inhibitor-172) is a voltage-independent, selective CFTR inhibitor.</p>Fórmula:C18H10F3NO3S2Pureza:98% - 99.72%Forma y color:SolidPeso molecular:409.4ULK-101
CAS:<p>ULK-101 is a potent and selective ULK1 inhibitor ( IC50s: 8.3/30 nM for ULK1/ULK2). It can suppress autophagy.</p>Fórmula:C22H16F4N4OSPureza:97.55% - 99.94%Forma y color:SolidPeso molecular:460.45Sertaconazole nitrate
CAS:<p>Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.</p>Fórmula:C20H15Cl3N2OS·HNO3Pureza:98.66% - 99.65%Forma y color:SolidPeso molecular:500.78Syringin
CAS:<p>Syringin (eleutheroside-b) is a compound with antitumor, antiproliferative, immunomodulatory and platelet aggregation inhibiting effects.</p>Fórmula:C17H24O9Pureza:98.89% - 99.56%Forma y color:SolidPeso molecular:372.37PATULIN
CAS:<p>Patulin (Claviform) is a mycotoxin produced by a variety of molds commonly found in rotting apples, including Aspergillus and Penicillium.</p>Fórmula:C7H6O4Pureza:99.91% - 99.98%Forma y color:Compact Prisms Or Thick Plates From Ether Or Chloroform White CrystallinePeso molecular:154.12Purmorphamine
CAS:<p>Purmorphamine (Shh Signaling Antagonist VI), which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo.</p>Fórmula:C31H32N6O2Pureza:97.19% - 99.48%Forma y color:Light Tan SolidPeso molecular:520.62Regorafenib monohydrate
CAS:<p>Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine</p>Fórmula:C21H17ClF4N4O4Pureza:99.69%Forma y color:SolidPeso molecular:500.83Genipin
CAS:<p>Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.</p>Fórmula:C11H14O5Pureza:99.09% - 99.21%Forma y color:SolidPeso molecular:226.23VER-155008
CAS:<p>VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively.</p>Fórmula:C25H23Cl2N7O4Pureza:97.03% - 99.55%Forma y color:SolidPeso molecular:556.4
