Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1428 productos de "Autofagia"
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Isosorbide Mononitrate
CAS:<p>Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.</p>Fórmula:C6H9NO6Pureza:98.16%Forma y color:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionPeso molecular:191.14Quizartinib
CAS:<p>Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.</p>Fórmula:C29H32N6O4SPureza:98% - 99.42%Forma y color:SolidPeso molecular:560.67Cediranib
CAS:<p>Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.</p>Fórmula:C25H27FN4O3Pureza:97.21% - 99.94%Forma y color:SolidPeso molecular:450.51STO-609
CAS:<p>STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.</p>Fórmula:C19H10N2O3Pureza:97.14% - 98.8%Forma y color:SolidPeso molecular:314.29Tanespimycin
CAS:<p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>Fórmula:C31H43N3O8Pureza:99.07% - 99.83%Forma y color:Dark Purple SolidPeso molecular:585.69Embelin
CAS:<p>Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).</p>Fórmula:C17H26O4Pureza:97.07% - 99.88%Forma y color:SolidPeso molecular:294.39Dynasore
CAS:<p>Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.</p>Fórmula:C18H14N2O4Pureza:95.85% - 99.22%Forma y color:SolidPeso molecular:322.31GNE-9605
CAS:<p>GNE-9605 is a highly effective, specifical, and brain-penetrant LRRK2 inhibitor (IC50: 19 nM).</p>Fórmula:C17H20ClF4N7OPureza:98.55% - 98.75%Forma y color:SolidPeso molecular:449.83NH125
CAS:<p>NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.</p>Fórmula:C27H45IN2Pureza:98.60%Forma y color:SolidPeso molecular:524.56Sertindole
CAS:<p>Sertindole, atypical antipsychotic, targets D2, 5-HT1D, 5-HT2A, 5-HT2C receptors (Kds: 2.7, 20, 0.14, 6 nM).</p>Fórmula:C24H26ClFN4OPureza:99.87% - 99.92%Forma y color:Off-White To Pale Yellow SolidPeso molecular:440.94QX77
CAS:<p>QX77 is a chaperone-mediated autophagy (CMA) activator.</p>Fórmula:C16H13ClN2O2Pureza:98.21%Forma y color:SolidPeso molecular:300.74Zoledronic Acid
CAS:<p>Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐，能抑制破骨细胞的分化和凋亡，具有高效的抗骨质再吸收活性，也有抗癌作用。</p>Fórmula:C5H10N2O7P2Pureza:98% - 99.93%Forma y color:White Crystalline PowderPeso molecular:272.09VO-Ohpic trihydrate
CAS:<p>VO-Ohpic trihydrate (VO-Ohpic) is a potent inhibitor of PTEN (phosphatase and tensin homolog) with IC50 of 35 nM.</p>Fórmula:C12H9N2O8V·3H2O·HPureza:>99.99%Forma y color:SolidPeso molecular:415.2BGT226
CAS:<p>BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.</p>Fórmula:C28H25F3N6O2Pureza:95.74% - 99.51%Forma y color:SolidPeso molecular:534.53UNBS5162
CAS:<p>UNBS5162 (UNBS-5162) is a novel naphthalimide that decreases CXCL chemokine expression in experimental prostate cancers.</p>Fórmula:C17H18N4O3Pureza:98.37% - 99.97%Forma y color:SolidPeso molecular:326.35Vinorelbine ditartrate
CAS:<p>Vinorelbine ditartrate (KW-2307) is a natural alkaloid and an anti-mitotic agent. Vinorelbine ditartrate has anti-tumor activity. Cost-effective and quality-assured.</p>Fórmula:C45H54N4O8·2C4H6O6Pureza:98% - 99.86%Forma y color:White To Off-White Crystalline PowderPeso molecular:1079.11PX-478
CAS:<p>PX-478 is a HIF-1α inhibitor with selectivity, oral activity, and blood-brain barrier permeability.</p>Fórmula:C13H20Cl4N2O3Pureza:97% - 99.79%Forma y color:SolidPeso molecular:394.12Schisandrin
CAS:<p>Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.</p>Fórmula:C24H32O7Pureza:98.97% - 99.32%Forma y color:White PowderPeso molecular:432.51MRT68921 HCl
CAS:<p>MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM, respectively).</p>Fórmula:C25H34N6O·HClPureza:99.86% - 99.98%Forma y color:SolidPeso molecular:471.04Rotenone
CAS:<p>Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.</p>Fórmula:C23H22O6Pureza:89.58% - 99.88%Forma y color:Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Peso molecular:394.42
