Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1428 productos de "Autofagia"
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NVP-AEW541
CAS:<p>NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based</p>Fórmula:C27H29N5OPureza:98.7% - 99.86%Forma y color:SolidPeso molecular:439.55Oxyresveratrol
CAS:<p>1.</p>Fórmula:C14H12O4Pureza:98.09% - 99.69%Forma y color:Yellow SolidPeso molecular:244.24CX546
CAS:<p>CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.</p>Fórmula:C14H17NO3Pureza:99.75%Forma y color:SolidPeso molecular:247.29BX795
CAS:<p>BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.</p>Fórmula:C23H26IN7O2SPureza:98% - 99.57%Forma y color:SolidPeso molecular:591.47SMER28
CAS:<p>SMER28 triggers autophagy in cells without mTOR, blocking amyloid beta buildup.</p>Fórmula:C11H10BrN3Pureza:99.94% - >99.99%Forma y color:SolidPeso molecular:264.12ZSTK474
CAS:<p>PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potential</p>Fórmula:C19H21F2N7O2Pureza:98.29% - 99.95%Forma y color:White PowderPeso molecular:417.41GW 4064
CAS:<p>GW 4064 is an effective farnesoid X receptor (FXR) agonist (EC50 =65 nM).</p>Fórmula:C28H22Cl3NO4Pureza:98% - 99.94%Forma y color:SolidPeso molecular:542.84Afatinib
CAS:<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Fórmula:C24H25ClFN5O3Pureza:98.56% - 99.9%Forma y color:Off-White SolidPeso molecular:485.94Mirdametinib
CAS:<p>Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity.</p>Fórmula:C16H14F3IN2O4Pureza:99.11% - 99.63%Forma y color:White PowderPeso molecular:482.19GSK621
CAS:<p>GSK621 is a specific and potent AMPK activator.</p>Fórmula:C26H20ClN3O5Pureza:97.02% - 97.05%Forma y color:SolidPeso molecular:489.91Tenovin-1
CAS:<p>Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.</p>Fórmula:C20H23N3O2SPureza:99.33%Forma y color:SolidPeso molecular:369.48Cyclovirobuxine D
CAS:<p>Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.</p>Fórmula:C26H46N2OPureza:97.78% - 98%Forma y color:SolidPeso molecular:402.665-Aminolevulinic acid hydrochloride
CAS:<p>5-Aminolevulinic acid hydrochloride (5-ALA) serves as an intermediate in the body's heme biosynthesis and is the universal precursor of tetrapyrroles.</p>Fórmula:C5H10ClNO3Pureza:98% - 99.97%Forma y color:White To Pale Yellow Crystals OrPeso molecular:167.59Idelalisib
CAS:<p>Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM).</p>Fórmula:C22H18FN7OPureza:98% - 99.39%Forma y color:SolidPeso molecular:415.42Ulipristal acetate
CAS:Ulipristal acetate (CDB-2914) is an oral selective progesterone modulator used for emergency contraception and suppressing uterine growths.Fórmula:C30H37NO4Pureza:98.83% - 99.94%Forma y color:SolidPeso molecular:475.62Azithromycin
CAS:<p>Azithromycin (CP 62993) is a macrolide antibiotic that primarily targets the 50S subunit of bacterial ribosomes. High-Quality, Low-Cost!</p>Fórmula:C38H72N2O12Pureza:99.9% - 99.97%Forma y color:White To Off-White Solid CrystallinePeso molecular:748.98Carfilzomib
CAS:<p>Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.</p>Fórmula:C40H57N5O7Pureza:99.6% - 99.84%Forma y color:SolidPeso molecular:719.91UM-164
CAS:<p>UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.</p>Fórmula:C30H31F3N8O3SPureza:98.72% - 99.52%Forma y color:SolidPeso molecular:640.68Nidufexor
CAS:<p>Nidufexor is an agonist for the farnesoid X receptor (FXR).</p>Fórmula:C27H22ClN3O4Pureza:98.67%Forma y color:SolidPeso molecular:487.93E-64
CAS:<p>E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.</p>Fórmula:C15H27N5O5Pureza:98% - 99.95%Forma y color:White SolidPeso molecular:357.41
