Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1459 productos de "Autofagia"
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TAK-779
CAS:<p>TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).</p>Fórmula:C33H39ClN2O2Pureza:99.21%Forma y color:SolidPeso molecular:531.13Polyphyllin I
CAS:<p>Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,</p>Fórmula:C44H70O16Pureza:98% - 99.5%Forma y color:SolidPeso molecular:855.02JMS-17-2
CAS:<p>JMS-17-2 is a potent and selective antagonist of CX3CR1( IC50 : 0.32 nM).</p>Fórmula:C25H26ClN3OPureza:98.7% - 99.44%Forma y color:SolidPeso molecular:419.95TC14012 acetate
TC14012 acetate is a serum-stable derivative of T140 which is a selective and peptidomimetic CXCR4 antagonist with an IC50 of 19.3 nM.Fórmula:C92H144N34O21S2Pureza:98.33% - 99.71%Forma y color:SolidPeso molecular:2126.47MSX-130
CAS:<p>MSX-130 is CXCR4 Antagonist.</p>Fórmula:C36H26N4Pureza:99.19%Forma y color:SolidPeso molecular:514.62SRT3109
CAS:SRT3109 is a CXCR2 ligand used in the treatment of chemokine mediated diseases and conditions.Fórmula:C18H23F2N5O4S2Pureza:99.65% - 99.92%Forma y color:SolidPeso molecular:475.53Plerixafor
CAS:<p>Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.</p>Fórmula:C28H54N8Pureza:99.17% - >99.99%Forma y color:SolidPeso molecular:502.78AZD-5069
CAS:<p>AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).</p>Fórmula:C18H22F2N4O5S2Pureza:98.38% - 98.63%Forma y color:SolidPeso molecular:476.52Plerixafor octahydrochloride
CAS:<p>Plerixafor octahydrochloride mobilizes HSCs by blocking SDF-1alpha/CXCR4 interaction, facilitating their release into circulation.</p>Fórmula:C28H62Cl8N8Pureza:98.01% - 99.79%Forma y color:SolidPeso molecular:794.46SX-682
CAS:SX-682 is an orally available allosteric inhibitor of CXCR1 and CXCR2.Cost-effective and quality-assured.Fórmula:C19H14BF4N3O4SPureza:98.19% - 99.61%Forma y color:SolidPeso molecular:467.2Isobavachalcone
CAS:<p>Isobavachalcone (Corylifolinin) is a chalcone constituent of Angelica keiskei, has potent anti-inflammatory activity, possible can ameliorate neuronal injury in</p>Fórmula:C20H20O4Pureza:98% - 99.76%Forma y color:SolidPeso molecular:324.37HG-10-102-01
CAS:<p>HG-10-102-01 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 of 20.3 nM).</p>Fórmula:C17H20ClN5O3Pureza:99.59%Forma y color:SolidPeso molecular:377.83Lucanthone
CAS:<p>Lucanthone (Lucanthonum) is an inhibitor of Apurinic endonuclease-1 (APE-1).</p>Fórmula:C20H24N2OSPureza:99.92%Forma y color:Yellow Crystals From Alcohol SolidPeso molecular:340.48Pennogenin 3-O-β-chacotrioside
CAS:<p>Pennogenin 3-O-beta-chacotrioside from Paris polyphylla fights colorectal cancer, boosting autophagy proteins LC3 and Beclin-1.</p>Fórmula:C45H72O17Pureza:99.69% - 99.77%Forma y color:SolidPeso molecular:885.04RITA
CAS:<p>RITA (NSC-652287) forms DNA-DNA/protein cross-links without DNA breaks; disrupts p53/Mdm2 like nutlin-3.</p>Fórmula:C14H12O3S2Pureza:98.49% - 99.55%Forma y color:SolidPeso molecular:292.374EGI-1
CAS:<p>4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).</p>Fórmula:C18H12Cl2N4O4SPureza:96.8% - 99.12%Forma y color:SolidPeso molecular:451.28Bortezomib
CAS:Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.Fórmula:C19H25BN4O4Pureza:97.79% - >99.99%Forma y color:Yellow SolidPeso molecular:384.24CZC-25146 hydrochloride
CAS:<p>CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.</p>Fórmula:C22H26ClFN6O4SPureza:98.76%Forma y color:SolidPeso molecular:525Danshensu
CAS:<p>Danshensu (Dan shen suan A) is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.</p>Fórmula:C9H10O5Pureza:98.4% - 99.74%Forma y color:SolidPeso molecular:198.17SKF-96365 hydrochloride
CAS:SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFórmula:C22H27ClN2O3Pureza:99.47% - 99.92%Forma y color:SolidPeso molecular:402.91
