Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1488 productos de "Autofagia"
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IKK 16 hydrochloride
CAS:IKK 16 hydrochloride, a potent IKK1/2 and LRRK2 inhibitor, IC50s: 40-200 nM and 50 nM respectively.Fórmula:C28H30ClN5OSForma y color:SolidPeso molecular:520.09Pazopanib-d6
CAS:Pazopanib-d6 is a deuterated compound of Pazopanib.Fórmula:C21H17D6N7O2SPeso molecular:443.56Venetoclax-d8
CAS:Venetoclax-d8 (ABT-199-d8) is a deuterated form of Venetoclax, a potent, selective, and orally active Bcl-2 inhibitor that induces autophagy and apoptosis.Fórmula:C45H42D8ClN7O7SForma y color:SolidPeso molecular:876.49Peptide R TFA
<p>Peptide R (TFA) is a synthetic and specific CXCR4 antagonist. It demonstrates excellent tumor stroma remodeling capabilities and is applicable in research on solid tumors, such as glioblastoma.</p>Fórmula:C39H57N13O8S2·xC2HF3O2Forma y color:SolidPeso molecular:900.08 (free base)Brivanib
CAS:Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold againstFórmula:C19H19FN4O3Pureza:98.87%Forma y color:SolidPeso molecular:370.38Cediranib maleate
CAS:Cediranib maleate (AZD2171 maleate) is a VEGFR2 inhibitor that inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit.Fórmula:C29H31FN4O7Forma y color:SolidPeso molecular:566.58Resveratrol analog 1
CAS:Resveratrol analog 1 is a natural product analog of resveratrol, which has more significant anti-leukemic activity than resveratrol.Fórmula:C14H11FO2Pureza:98.42%Forma y color:SolidPeso molecular:230.23Rupatadine
CAS:Rupatadine (UR-12592, rupatadine) is a potent and orally available dual antagonist of PAF and histamine H1 receptors ,allergic and anti-inflammatory.Fórmula:C26H26ClN3Pureza:99.87%Forma y color:SolidPeso molecular:415.96Silibinin-d3
Silibinin-d3 is the deuterium-labelled compound of silibinin, used for isotope tracing. Silibinin inhibit cancer cell proliferation and migration.Fórmula:C25H22O10Forma y color:SolidPeso molecular:485.46Megestrol Acetate-d3
CAS:Megestrol Acetate-d3 is a deuterated compound of Megestrol Acetate. Megestrol Acetate has a CAS number of 595-33-5. Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia.Fórmula:C24H29D3O4Forma y color:SolidPeso molecular:387.53Afatinib D6
CAS:Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.Fórmula:C24H25ClFN5O3Forma y color:SolidPeso molecular:491.98Dexamethasone-d5
CAS:<p>Dexamethasone-d5 is a deuterated compound of Dexamethasone.</p>Fórmula:C22H24D5FO5Forma y color:SolidPeso molecular:397.49Pyrazinamide-d3
CAS:Pyrazinamide-d3 is a deuterated compound of Pyrazinamide. Pyrazinamide has a CAS number of 98-96-4. Pyrazinamide, an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.Fórmula:C5D3H2N3OForma y color:SolidPeso molecular:126.13V-9302 hydrochloride
CAS:V-9302 hydrochloride is a competitive transmembrane glutamine flux antagonist that selectively targets the amino acid transporter ASCT2/SLC1A5.Fórmula:C34H39ClN2O4Pureza:97.31%Forma y color:SolidPeso molecular:575.14Thiacloprid
CAS:Thiacloprid: insecticide targeting insect nAChRs, IC50 - Drosophila: 2.7 nM, Mouse α4β2 nAChRs: 860 nM.Fórmula:C10H9ClN4SPureza:98.66% - 99.95%Forma y color:Yellowish Crystalline PowderPeso molecular:252.72Isorhapontigenin
CAS:Isorhapontigenin: a methoxylated stilbenoid isomer of rhapontigenin, similar to resveratrol, present in Gnetum spp. and Aiphanes aculeata seeds.Fórmula:C15H14O4Pureza:98.49% - 99.85%Forma y color:Off White Crystals PowerPeso molecular:258.27Valproic Acid
CAS:Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.Fórmula:C8H16O2Pureza:97.78% - 99%Forma y color:Colourless To Pale Yellow Liquid ViscousPeso molecular:144.21Ginkgolide K
CAS:Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.Fórmula:C20H22O9Pureza:99.44% - 99.72%Forma y color:SolidPeso molecular:406.38PF-04457845
CAS:PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).Fórmula:C23H20F3N5O2Pureza:>99.99%Forma y color:SolidPeso molecular:455.43Ginsenoside F2
CAS:Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.Fórmula:C42H72O13Pureza:99.04% - 99.3%Forma y color:SolidPeso molecular:785.01
