Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1529 productos para "Autofagia".
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TRAF6 peptide TFA
TRAF6 peptide TFA, a specific inhibitor of the TRAF6-p62 interaction, significantly inhibits NGF-dependent ubiquitination of TrkA.Fórmula:C145H238N34O44·xC2HF3O2Pureza:98%Forma y color:SolidPeso molecular:3161.64 (free acid)Rosuvastatin-D3 Sodium
CAS:Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).Fórmula:C22H24D3FN3NaO6SPureza:98%Forma y color:SolidPeso molecular:506.54Loperamide-D6 hydrochloride
CAS:Loperamide D6 HCl: Deuterium-enriched opioid for diarrhea.Fórmula:C29H34Cl2N2O2Pureza:98%Forma y color:SolidPeso molecular:519.54Loperamide hydrochloride (Standard)
CAS:Loperamide hydrochloride (Standard) is the standard substance of Loperamide hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.Fórmula:C29H34Cl2N2O2Peso molecular:513.50Wortmannin (Standard)
CAS:Wortmannin (Standard) is the standard substance of Wortmannin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible. Wortmannin is also an inhibitor of PlK1 and PlK3 (IC50=5.8/48 nM) that blocks autophagy.Fórmula:C23H24O8Peso molecular:428.43Ezetimibe-D4
CAS:Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activationFórmula:C24H21F2NO3Pureza:98%Forma y color:SolidPeso molecular:413.45Nitrendipine (Standard)
CAS:Nitrendipine (Standard) is the standard substance of Nitrendipine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nitrendipine (BAY-E-5009) is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.Fórmula:C18H20N2O6Peso molecular:360.36Imiquimod (Standard)
CAS:Imiquimod (Standard) is the standard substance of Imiquimod, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Imiquimod (R 837) is an immune response modifier and a toll-like receptor 7 (TLR7) agonist with antiviral and antitumor effects. It is used in the study of external genital warts, perianal warts, cancer, and COVID-19, and is commonly employed to induce psoriasis models.Fórmula:C14H16N4Peso molecular:240.30Pemetrexed disodium heptahydrate
CAS:Pemetrexed disodium heptahydrate (LY231514) is an antifolate that inhibits TS, DHFR and GARFT, inhibits precursor purine and pyrimidine nucleotides.Fórmula:C20H33N5Na2O13Pureza:99.78%Forma y color:White SolidPeso molecular:597.49Rapalink-1
CAS:Rapalink-1 is an mTOR inhibitor that inhibits the mTORC1-4E-BP1 pathway in mice.Fórmula:C91H138N12O24Pureza:98%Forma y color:White ViscousPeso molecular:1784.14BI-9627 hydrochloride
CAS:BI-9627 hydrochloride is a potent NHE1 inhibitor (IC₅₀ 6 nM, 31 nM), highly selective over NHE2, inactive on NHE3, regulating pH and autophagy.Fórmula:C16H20ClF3N4O2Pureza:99.91%Forma y color:White SolidPeso molecular:392.8Erlotinib-D6 hydrochloride
CAS:Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.Fórmula:C22H24ClN3O4Pureza:98%Forma y color:SolidPeso molecular:435.93PS372424 hydrochloride
CAS:PS372424 hydrochloride,CXCR3 agonist. Anti-inflammatory. Inhibits T-cell migration.Fórmula:C33H45ClN6O4Pureza:95.03%Forma y color:Transparent ViscousPeso molecular:625.2Ponatinib-D8
CAS:Ponatinib D8 is a deuterium-enriched, oral multi-kinase inhibitor (Abl, PDGFRα, VEGFR2, FGFR1, Src; IC50s: 0.37-5.4 nM).Fórmula:C29H27F3N6OPureza:98%Forma y color:SolidPeso molecular:540.61Guanidine hydrochloride (Standard)
CAS:Guanidine hydrochloride (Standard) is the standard substance of Guanidine hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Guanidine hydrochloride (Aminoformamidine Hydrochloride) is a strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant.Fórmula:CH6ClN3Forma y color:SolidPeso molecular:95.53Clotrimazole (Standard)
CAS:Clotrimazole (Standard) is the standard substance of Clotrimazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Clotrimazole (FB 5097), an imidazole derivative with a broad spectrum of antimycotic activity, inhibits biosynthesis of the sterol ergostol.Fórmula:C22H17ClN2Forma y color:SolidPeso molecular:344.84Atorvastatin hemicalcium salt (Standard)
CAS:Atorvastatin hemicalcium salt (Standard) is the standard substance of Atorvastatin hemicalcium salt, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an HMG-CoA reductase inhibitor with oral activity. Atorvastatin hemicalcium salt is used to lower cholesterol.Fórmula:C33H34FN2O5CaForma y color:SolidPeso molecular:577.67Colistin sulfate (Standard)
CAS:Colistin sulfate (Standard) is the standard substance of Colistin sulfate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.Forma y color:SolidRegorafenib-D3
CAS:Regorafenib D3 is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor inhibitor of tyrosine kinase.Fórmula:C21H15ClF4N4O3Pureza:98%Forma y color:SolidPeso molecular:485.83Anti-LRRK2 Antibody (1C773)
Anti-LRRK2 Antibody (1C773) is an antibody targeting LRRK2. Anti-LRRK2 Antibody (1C773) can be used in ELISA, IHC.Forma y color:Odour Liquid
