Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1431 productos de "Autofagia"
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Nesolicaftor
CAS:<p>Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.</p>Fórmula:C18H18N4O4Pureza:99.79%Forma y color:SolidPeso molecular:354.36UBCS039
CAS:<p>UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)</p>Fórmula:C16H13N3Pureza:98.31%Forma y color:SolidPeso molecular:247.29Ataluren
CAS:<p>Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.</p>Fórmula:C15H9FN2O3Pureza:99.16% - 99.84%Forma y color:SolidPeso molecular:284.24SRT 1720
CAS:<p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.</p>Fórmula:C25H23N7OSPureza:98.84%Forma y color:SolidPeso molecular:469.56BAY 11-7082
CAS:BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).Fórmula:C10H9NO2SPureza:98% - 99.92%Forma y color:SolidPeso molecular:207.25L-779450
CAS:L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively.Fórmula:C20H14ClN3OPureza:≥95%Forma y color:SolidPeso molecular:347.8Gemcitabine hydrochloride
CAS:Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Fórmula:C9H11F2N3O4·HClPureza:99.28% - 99.98%Forma y color:White Crystalline Granular OdorlessPeso molecular:299.66Vps34-PIK-III
CAS:<p>Vps34-PIK-III (VPS34-IN2), a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and results in the stabilization of autophagy substrates.</p>Fórmula:C17H17N7Pureza:98.39% - 98.43%Forma y color:SolidPeso molecular:319.36Rottlerin
CAS:<p>Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.</p>Fórmula:C30H28O8Pureza:97.41% - 99.44%Forma y color:Orange To Brown PowderPeso molecular:516.54Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Fórmula:C18H19N3O3S·HClPureza:99.63% - 99.79%Forma y color:SolidPeso molecular:393.89Olaparib
CAS:<p>View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.</p>Fórmula:C24H23FN4O3Pureza:98% - >99.99%Forma y color:SolidPeso molecular:434.46BL-918
CAS:<p>BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.</p>Fórmula:C23H15F8N3OSPureza:99.4% - 99.89%Forma y color:SolidPeso molecular:533.44TPEN
CAS:<p>TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.</p>Fórmula:C26H28N6Pureza:98% - 99.72%Forma y color:White Crystalline PowderPeso molecular:424.54RSVA405
CAS:<p>RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor</p>Fórmula:C17H20N4O2Pureza:99.30%Forma y color:SolidPeso molecular:312.37Sevelamer hydrochloride
CAS:<p>Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption</p>Fórmula:(C3H7N·C3H5ClO·HCl)xPureza:98%Forma y color:SolidPeso molecular:186.08Cucurbitacin B
CAS:<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Fórmula:C32H46O8Pureza:97.1% - 99.33%Forma y color:SolidPeso molecular:558.7Zebularine
CAS:<p>Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.</p>Fórmula:C9H12N2O5Pureza:99.04% - >99.99%Forma y color:SolidPeso molecular:228.2Degrasyn
CAS:<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Fórmula:C19H18BrN3OPureza:98.32% - 99.98%Forma y color:SolidPeso molecular:384.27Cryptotanshinone
CAS:<p>Cryptotanshinone: STAT3 inhibitor, IC50 4.6 μM; blocks STAT3 Tyr705 phosphorylation, minor effect on Ser727, no impact on STAT1/5.</p>Fórmula:C19H20O3Pureza:97.94% - ≥95%Forma y color:Orange Needle CrystalPeso molecular:296.36Idarubicin hydrochloride
CAS:Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).Fórmula:C26H27NO9·HClPureza:98.91% - 99.96%Forma y color:SolidPeso molecular:533.95
