Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1430 productos de "Autofagia"
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yangonin
CAS:<p>Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.</p>Fórmula:C15H14O4Pureza:98.82% - 99.55%Forma y color:Pale Yellow PowderPeso molecular:258.27Torkinib
CAS:<p>Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).</p>Fórmula:C16H16N6OPureza:99.11%Forma y color:SolidPeso molecular:308.34CCT007093
CAS:<p>CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).</p>Fórmula:C15H12OS2Pureza:98% - 99.88%Forma y color:SolidPeso molecular:272.39Resatorvid
CAS:<p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>Fórmula:C15H17ClFNO4SPureza:99.31% - >99.99%Forma y color:SolidPeso molecular:361.82Fulvestrant
CAS:<p>Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30.</p>Fórmula:C32H47F5O3SPureza:99.1% - >99.99%Forma y color:White PowderPeso molecular:606.77Flavopiridol hydrochloride
CAS:<p>Flavopiridol hydrochloride (MDL 107826A), an inhibitor of cyclin-dependent kinase, is a synthetic N-methylpiperidinyl chlorophenyl flavone compound.</p>Fórmula:C21H21Cl2NO5Pureza:98.87% - 99.88%Forma y color:SolidPeso molecular:438.3Orthanilamide
CAS:Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.Fórmula:C6H8N2O2SPureza:99.72% - 99.96%Forma y color:White To Pale Cream Crystalline Powder Or CrystalsPeso molecular:172.2AGN 193109
CAS:<p>AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).</p>Fórmula:C28H24O2Pureza:99.87% - 99.89%Forma y color:SolidPeso molecular:392.49MPP+ iodide
CAS:<p>MPP+ iodide, a neurotoxin byproduct, mimics Parkinson's by killing substantia nigra neurons and affecting neuron transporters, inducing cell death.</p>Fórmula:C12H12INPureza:99.49% - 99.96%Forma y color:SolidPeso molecular:297.13Telaglenastat
CAS:<p>Telaglenastat (CB 839) (IC50 of 24 nM), an effective, specific, and oral inhibitor, which is bioavailable glutaminase, for recombinant human GAC.</p>Fórmula:C26H24F3N7O3SPureza:97.57% - 99.89%Forma y color:SolidPeso molecular:571.57GSK2578215A
CAS:GSK2578215A is a potent and selective LRRK2 kinase inhibitor.Fórmula:C24H18FN3O2Pureza:99.57% - 99.94%Forma y color:SolidPeso molecular:399.42Imatinib
CAS:<p>Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kit</p>Fórmula:C29H31N7OPureza:99.42% - 99.94%Forma y color:Off White PowderPeso molecular:493.6Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Fórmula:C19H23NO4Pureza:99.02% - 99.73%Forma y color:White PowderPeso molecular:329.39Demethoxycurcumin
CAS:<p>Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.</p>Fórmula:C20H18O5Pureza:94.54% - 99.86%Forma y color:SolidPeso molecular:338.35Ginkgolide K
CAS:<p>Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.</p>Fórmula:C20H22O9Pureza:99.44% - 99.72%Forma y color:SolidPeso molecular:406.38Aloperine
CAS:<p>Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.</p>Fórmula:C15H24N2Pureza:98% - 99.88%Forma y color:Yellow Crystalline PowderPeso molecular:232.36Arglabin
CAS:<p>Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.</p>Fórmula:C15H18O3Pureza:98.97% - 99.62%Forma y color:SolidPeso molecular:246.3Bilobalide
CAS:<p>Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.</p>Fórmula:C15H18O8Pureza:98.81% - 99.92%Forma y color:White SolidPeso molecular:326.3Clematichinenoside AR
CAS:<p>Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.</p>Fórmula:C82H134O43Pureza:99.04% - 99.69%Forma y color:SolidPeso molecular:1807.92Apocynin
CAS:<p>Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).</p>Fórmula:C9H10O3Pureza:99.71% - 99.98%Forma y color:Yellowish To Brown PowderPeso molecular:166.17
