Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1430 productos de "Autofagia"
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HA15
CAS:<p>HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.</p>Fórmula:C23H22N4O3S2Pureza:99.77% - 99.86%Forma y color:SolidPeso molecular:466.58Dimethyl fumarate
CAS:<p>Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.</p>Fórmula:C6H8O4Pureza:90.51% - >99.99%Forma y color:White To Off-White Powder White Crystalline PowderPeso molecular:144.13ISRIB (trans-isomer)
CAS:<p>ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.</p>Fórmula:C22H24Cl2N2O4Pureza:97.86% - 99.27%Forma y color:SolidPeso molecular:451.34Salubrinal
CAS:<p>Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).</p>Fórmula:C21H17Cl3N4OSPureza:97.25% - >99.99%Forma y color:SolidPeso molecular:479.81Binimetinib
CAS:<p>Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C17H15BrF2N4O3Pureza:98.03% - >99.99%Forma y color:SolidPeso molecular:441.23Reparixin
CAS:<p>Reparixin inhibits CXCR1 (IC50=1 nM) strongly, CXCR2 weakly (IC50=100 nM), and it's a CXCL8 receptor blocker.</p>Fórmula:C14H21NO3SPureza:98% - 99.89%Forma y color:SolidPeso molecular:283.39Daurisoline
CAS:<p>Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.</p>Fórmula:C37H42N2O6Pureza:98% - 99.96%Forma y color:Light Yellow PowderPeso molecular:610.74Bigelovin
CAS:<p>Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.</p>Fórmula:C17H20O5Pureza:99.61% - 99.72%Forma y color:SolidPeso molecular:304.34Britannin
CAS:<p>Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.</p>Fórmula:C19H26O7Pureza:98% - 99.98%Forma y color:SolidPeso molecular:366.41Verteporfin
CAS:<p>Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.</p>Fórmula:C41H42N4O8Pureza:95.37% - 99.82%Forma y color:Dark Green To Black SolidPeso molecular:718.79Ralimetinib dimesylate
CAS:<p>Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.</p>Fórmula:C24H29FN6·2CH4O3SPureza:98% - 99.38%Forma y color:SolidPeso molecular:612.74Hydroxyprogesterone caproate
CAS:<p>Hydroxyprogesterone caproate (Delalutin) is a synthetic progestin that activates progesterone receptors and inhibits ovulation.</p>Fórmula:C27H40O4Pureza:99.70%Forma y color:White Or Almost White Crystalline PowerPeso molecular:428.60Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Fórmula:C10H7N3O4SPureza:98.89% - 99.28%Forma y color:SolidPeso molecular:265.25Bardoxolone Methyl
CAS:<p>Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-</p>Fórmula:C32H43NO4Pureza:97.81% - 99.09%Forma y color:SolidPeso molecular:505.69BMS-582949 hydrochloride
CAS:<p>The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).</p>Fórmula:C22H27ClN6O2Pureza:97.57% - 98.75%Forma y color:SolidPeso molecular:442.95Tazarotene
CAS:<p>Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.</p>Fórmula:C21H21NO2SPureza:97.01% - 99.14%Forma y color:White SolidPeso molecular:351.46Deguelin
CAS:<p>Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.</p>Fórmula:C23H22O6Pureza:96.39% - 99.29%Forma y color:SolidPeso molecular:394.42BIA 10-2474
CAS:<p>BIA 10-2474 is a long-acting reversible inhibitor of FAAH that increases levels of the neurotransmitter anandamide in the nervous system.</p>Fórmula:C16H20N4O2Pureza:99.27%Forma y color:SolidPeso molecular:300.36Chenodeoxycholic Acid sodium salt
CAS:Chenodeoxycholic Acid sodium salt (CDCA sodium salt) is a bile acid in humans that activates the nuclear receptor FXR, rescues axonal degeneration of induced pluripotent stem cell-derived neurons in patients with spastic paraplegia type 5 and cerebral xanthomatosis, and can be used to study pancreatic necrosis.Fórmula:C24H39NaO4Pureza:99.68% - 99.72%Forma y color:SolidPeso molecular:414.55Meloxicam
CAS:<p>Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.</p>Fórmula:C14H13N3O4S2Pureza:97.09% - 99.60%Forma y color:Light Yellow SolidPeso molecular:351.40
