Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1428 productos de "Autofagia"
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Sulfosuccinimidyl oleate
CAS:<p>Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells.</p>Fórmula:C22H37NO7SPureza:98%Forma y color:SolidPeso molecular:459.6Ipsalazide
CAS:<p>Ipsalazide is a novel salicylazosulfapyridine analog for the treatment of inflammatory bowel disease.</p>Fórmula:C16H11N3Na2O6Pureza:99.43%Forma y color:SolidPeso molecular:387.25FR 167653 free base
CAS:<p>FR 167653 is an oral p38 MAPK inhibitor for inflammation, trauma, ischemia relief; it suppresses TNF-α, IL-1β.</p>Fórmula:C24H18FN5O2Pureza:98%Forma y color:SolidPeso molecular:427.43ROC-325
CAS:<p>ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.</p>Fórmula:C28H27ClN4OSPureza:99.26%Forma y color:SolidPeso molecular:503.06Xantocillin
CAS:<p>Xanthocillin is a marine agent. Xanthocillin also induces autophagy through inhibition of the MEK/ERK pathway.</p>Fórmula:C18H12N2O2Pureza:98%Forma y color:SolidPeso molecular:288.3AMD 3465
CAS:<p>AMD 3465 (GENZ-644494) blocks CXCR4, hinders X4 HIV replication (IC50: 1-10 nM), ineffective against R5 viruses, IC50: 0.75 nM (12G5 mAb), 18 nM (CXCL12AF647).</p>Fórmula:C24H38N6Pureza:98%Forma y color:SolidPeso molecular:410.60Olacaftor
CAS:<p>Olacaftor, also known as VX-440, is a protein modulator of cystic fibrosis transmembrane regulator (CFTR).</p>Fórmula:C29H34FN3O4SForma y color:SolidPeso molecular:539.66GPP78
CAS:<p>GPP78: Strong Nampt inhibitor, IC50 3.0 nM, depletes NAD. Kills SH-SY5Y cells, IC50 3.8 nM via autophagy. Anti-cancer and anti-inflammatory.</p>Fórmula:C27H29N5OPureza:98%Forma y color:SolidPeso molecular:439.55CXCR4 antagonist 5
CAS:<p>CXCR4 antagonist with IC50 of 8.8 nM, inhibits CXCL12-induced calcium increase and chemotaxis, with good safety and minimal CYP, hERG impact.</p>Fórmula:C21H30N6Forma y color:SolidPeso molecular:366.5RNF5 inhibitor inh-02
CAS:<p>RNF5 inhibitor inh-02 is a selective inhibitor of the ubiquitin ligase RNF5/RMA1, which can significantly rescue F508del-CFTR cystic fibrosis (CF).</p>Fórmula:C23H20N4SPureza:99.23%Forma y color:SolidPeso molecular:384.5Ivacaftor hydrate
CAS:<p>Ivacaftor hydrate is an orally bioavailable CFTR potentiator. It also is used for cystic fibrosis treatment.</p>Fórmula:C24H30N2O4Pureza:98%Forma y color:SolidPeso molecular:410.514Amsacrine
CAS:<p>Amsacrine (AMSA) (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells.</p>Fórmula:C21H19N3O3SPureza:99.2%Forma y color:Yellow Crystalline Powder SolidPeso molecular:393.46Autophagy inducer 3
CAS:<p>Autophagy Inducer 3 triggers selective cancer cell death via autophagy, sparing healthy cells.</p>Fórmula:C24H43NO2Forma y color:SolidPeso molecular:377.6Omeprazole Sodium
CAS:<p>Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.</p>Fórmula:C17H18N3NaO3SPureza:99.84%Forma y color:Clear In WaterPeso molecular:367.4AZ10397767
CAS:<p>AZ10397767: Potent CXCR2 blocker (IC50=1nM); lowers neutrophil infiltration in tumors in vitro/in vivo.</p>Fórmula:C15H14ClFN4O2S2Forma y color:SolidPeso molecular:400.88DK-1-49
CAS:<p>DK-1-49 is an autophagonizer. It causes accumulation of autophagy-associated LC3-II and enhanced levels of autophagosomes and acidic vacuoles.</p>Fórmula:C28H31N5O3S2Pureza:98%Forma y color:SolidPeso molecular:549.71CUR5g
CAS:<p>CUR5g is an autophagy inhibitor that inhibits migration and colony formation in A549 cells.</p>Fórmula:C22H20N2O2Pureza:98.92%Forma y color:SolidPeso molecular:344.41SR-17398
CAS:<p>SR-17398 is an inhibitor of Unc-51-Like Kinase 1 (ULK1) (IC50 = 22.4 uM).</p>Fórmula:C14H18N4OPureza:98%Forma y color:SolidPeso molecular:258.32SRT3190
CAS:<p>SRT3190 is an antagonist of CXCR2.</p>Fórmula:C18H23F2N5O4S2Pureza:98%Forma y color:SolidPeso molecular:475.53SCH 546738
CAS:<p>SCH 546738 is an orally available, selective and potent CXCR3 antagonist that attenuates the development of autoimmune diseases and delays graft rejection.</p>Fórmula:C23H31Cl2N7OPureza:98.67%Forma y color:SolidPeso molecular:492.45
