Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1428 productos de "Autofagia"
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K67
CAS:<p>K67 competitively inhibits the interaction between Nrf2-ETGE and Keap1 and can be used to study cancer.</p>Fórmula:C29H30N2O7S2Pureza:98.43%Forma y color:SolidPeso molecular:582.69ABTL-0812
CAS:<p>ABTL-0812 induces endoplasmic reticulum (ER) stress-mediated autophagy, and with anti-cancer activity.</p>Fórmula:C18H32O3Forma y color:SolidPeso molecular:296.44FC131
CAS:<p>CXCR4 antagonist</p>Fórmula:C36H47N11O6Pureza:98%Forma y color:SolidPeso molecular:729.83AGN 205728
CAS:<p>AGN 205728 is a potent and selective RARγ antagonist (Ki: 3 nM; IC95: 0.6 nM) and has no inhibition on RARα and RARβ.</p>Fórmula:C29H27NO3Pureza:98%Forma y color:SolidPeso molecular:437.53SR12418
CAS:<p>SR12418 is a specific synthetic ligand for REV-ERBα (IC50 = 68 nM) and REV-ERBβ (IC50 = 119 nM) in TR-FRET assays. inhibits IL-17A expression in EL4 cells.</p>Fórmula:C31H30FNO3Pureza:99.96%Forma y color:SolidPeso molecular:483.57GSK3-IN-3
CAS:<p>GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy.</p>Fórmula:C24H35N3O4Pureza:99.37%Forma y color:SolidPeso molecular:429.55Glaucocalyxin B
CAS:<p>Glaucocalyxin B is a diterpenoid isolated from Rabdosia japonica with anticancer and antitumor activity. It decreases the growth of HL-60 cells (IC50: 5.86 μM).</p>Fórmula:C22H30O5Pureza:99.13% - 99.35%Forma y color:SolidPeso molecular:374.47AMDE-1
CAS:<p>AMDE-1, an autophagy modulator, triggers Atg5-dependent autophagy, recruits Atg16, and induces LC3 lipidation.</p>Fórmula:C18H8ClF6N3Pureza:90%Forma y color:SolidPeso molecular:415.72(-)-Talarozole
CAS:<p>(-)-Talarozole is a potent retinoic acid metabolism inhibitor.</p>Fórmula:C21H23N5SForma y color:SolidPeso molecular:377.51(Rac)-AZD 6482
CAS:<p>(Rac)-AZD 6482 is the racemate of AZD 6482. AZD 6482 is a potent and selective inhibitor of p110β (IC50 of 0.69 nM).</p>Fórmula:C22H24N4O4Forma y color:SolidPeso molecular:408.45Evogliptin tartrate
CAS:<p>Evogliptin tartrate: Oral DPP-4 inhibitor, may treat atherosclerosis and diabetes.</p>Fórmula:C23H32F3N3O9Forma y color:SolidPeso molecular:551.51AMG 487 (S-enantiomer)
CAS:<p>AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist.</p>Fórmula:C32H28F3N5O4Pureza:98%Forma y color:SolidPeso molecular:603.59FAAH inhibitor 1
CAS:<p>FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.</p>Fórmula:C24H23N3O3S3Pureza:99.6%Forma y color:SolidPeso molecular:497.65VUF10132
CAS:<p>VUF10132 is a full inverse CXCR3 N3.35A agonist.</p>Fórmula:C19H13BrCl4N2O2Pureza:98%Forma y color:SolidPeso molecular:523.03(R)-Hydroxychloroquine
CAS:<p>(R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine is an agent of synthetic antimalarial.</p>Fórmula:C18H26ClN3OPureza:98%Forma y color:SolidPeso molecular:335.87CCT128930
CAS:<p>'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'</p>Fórmula:C18H20ClN5Pureza:99.07% - 99.18%Forma y color:SolidPeso molecular:341.84eIF4A3-IN-2
CAS:<p>eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.</p>Fórmula:C25H19Br2ClN4O2Pureza:98%Forma y color:SolidPeso molecular:602.71FKBP51F67V-selective antagonist Ligand2
CAS:<p>FKBP51F67V-selective antagonist Ligand2 (example 3-3), a potent ligand, selectively binds to the FKBP51 F67V variant, with no affinity for wild-type FKBP51 or</p>Fórmula:C43H56N2O10Pureza:98%Forma y color:SolidPeso molecular:760.91MDK-6983
CAS:<p>MDK-6983 (MDK-6983) is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.</p>Fórmula:C22H18Cl2N2O3Pureza:99.68%Forma y color:SolidPeso molecular:429.3AL 8697
CAS:<p>AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.</p>Fórmula:C21H21F3N4OPureza:99.55% - 99.89%Forma y color:SolidPeso molecular:402.41
