Receptor de endotelina
Los receptores de endotelina son GPCR que median los efectos de las endotelinas, péptidos vasoconstrictores potentes que desempeñan un papel significativo en la regulación del tono vascular, el control de la presión arterial y la proliferación celular. Los antagonistas de los receptores de endotelina se utilizan en el tratamiento de afecciones como la hipertensión arterial pulmonar y la insuficiencia cardíaca. Estos receptores también son objetivos importantes en la investigación sobre enfermedades cardiovasculares y cáncer. En CymitQuimica, ofrecemos una selección de moduladores de receptores de endotelina de alta calidad para apoyar su investigación en biología cardiovascular, oncología y fisiología vascular.
Se han encontrado 85 productos para "Receptor de endotelina".
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IRL-3630
CAS:IRL 3460 is an enantiomer.Fórmula:C31H40N4O6SPureza:98%Forma y color:SolidPeso molecular:596.74Atrial Natriuretic Peptide (ANP) (1-28), rat
CAS:Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.Fórmula:C128H205N45O39S2Pureza:98%Forma y color:SolidPeso molecular:3062.41ACT-373898
CAS:ACT-373898 is a metabolite of the endothelin (ET) receptor type A (ETA) and ETBdual antagonist macitentan .1Fórmula:C15H17BrN4O5SForma y color:SolidPeso molecular:445.29[Lys4] Sarafotoxin S6c
CAS:[Lys4] Sarafotoxin S6c: potent partial endothelin receptor agonist; causes pig coronary contraction, EC50=1.5 nM.Fórmula:C105H153N27O36S5Forma y color:SolidPeso molecular:2529.82[Asn18] Endothelin-1, human
CAS:[Asn18] Endothelin-1, human, a peptide, represents a predominant isoform of Endothelin, significantly contributing to the regulation of vascular function [1].Fórmula:C109H164N26O31S5Forma y color:SolidPeso molecular:2494.96Atrial natriuretic peptide (3-28) (human)
CAS:Atrial natriuretic peptide (3-28) (human) (ANP (3-28) (human)), a peptide hormone produced by the atrial myocardium, plays a critical role in the regulation ofFórmula:C118H187N43O36S3Pureza:98%Forma y color:SolidPeso molecular:2880.21IRL-1038
CAS:ETB endothelin receptor antagonistFórmula:C68H92N14O15S2Pureza:98%Forma y color:SolidPeso molecular:1409.67Sarafotoxin S6b
CAS:non-selective endothelin receptor agonistFórmula:C110H163N27O34S5Pureza:98%Forma y color:SolidPeso molecular:2567.96Sarafotoxin S6c
CAS:Highly selective ETB endothelin receptor agonist (Ki values are 0.29 and 28000 nM at ETB and ETA receptors respectively).Fórmula:C103H147N27O37S5Pureza:98%Forma y color:SolidPeso molecular:2516PD 142893
CAS:PD 142893 is a functional endothelin-stimulated vasoconstriction antagonist.Fórmula:C50H65N7O10Pureza:98%Forma y color:SolidPeso molecular:924.09BQ-3020 ammonium
BQ-3020 ammonium, a selective endothelin receptor (ET B receptor) agonist, demonstrates inhibition of [125 I] ET-1 binding to ET B receptors with an IC50 of 0.2Fórmula:C96H140N20O25S·xNH3Pureza:98%Forma y color:SolidPeso molecular:2006.32 (free base)IRL-1620
CAS:IRL-1620 is an effective and selective agonist of endothelin receptor type B (ETB) (Ki: 16 pM).Fórmula:C86H117N17O27Pureza:98%Forma y color:SolidPeso molecular:1820.974Sarafotoxin S6a
CAS:Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.Fórmula:C105H156N28O34S5Pureza:98%Forma y color:SolidPeso molecular:2514.85Endothelin-3 (Rat,Human) (TFA)
Endothelin-3 (Rat, Human) (TFA) is a 21-amino acid vasoactive peptide of endothelial origi, an agonist for the endothelin receptor type B (EDNRB).Fórmula:C123H169F3N26O35S4·xC2HF3O2Pureza:98%Forma y color:White SolidPeso molecular:2757.07 (free base)Macitentan
CAS:Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).Fórmula:C19H20Br2N6O4SPureza:98% - >99.99%Forma y color:White SolidPeso molecular:588.27BQ-123
CAS:BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.Fórmula:C31H42N6O7Pureza:98.36% - 99.22%Forma y color:White SolidPeso molecular:610.7Darusentan
CAS:Darusentan (Lu-135252) is a potent inhibitor of endothelin signaling and function in both large and small arteriesFórmula:C22H22N2O6Pureza:98.72%Forma y color:White SolidPeso molecular:410.43Ref: TM-T5458
2mg43,00€5mg65,00€1mL*10mM (DMSO)67,00€10mg100,00€25mg173,00€50mg288,00€100mg414,00€200mg583,00€BQ-788 sodium salt
CAS:BQ-788 sodium salt is a potent and selective antagonist of ETB receptor(ETB receptors with an IC50 of 1.2 nM in human Girrardi heart cells).Fórmula:C34H51N5NaO7Pureza:98.11%Forma y color:SolidPeso molecular:664.8Aprocitentan
CAS:Aprocitentan (ACT-132577) is ETA and ETB antagonist .Fórmula:C16H14Br2N6O4SPureza:99.17%Forma y color:White SolidPeso molecular:546.19Ref: TM-T7817
1mg55,00€5mg110,00€1mL*10mM (DMSO)135,00€10mg166,00€25mg295,00€50mg416,00€100mg622,00€200mg840,00€Ambrisentan sodium
CAS:Ambrosentan (BSF 208075) sodium is a selective and oral effective antagonist of ET type A receptor ( ETAR ).Fórmula:C22H21N2NaO4Forma y color:SolidPeso molecular:400.41
![[Lys4] Sarafotoxin S6c](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76302.webp&w=3840&q=75)
![[Asn18] Endothelin-1, human](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76329.webp&w=3840&q=75)
