Receptor de endotelina
Los receptores de endotelina son GPCR que median los efectos de las endotelinas, péptidos vasoconstrictores potentes que desempeñan un papel significativo en la regulación del tono vascular, el control de la presión arterial y la proliferación celular. Los antagonistas de los receptores de endotelina se utilizan en el tratamiento de afecciones como la hipertensión arterial pulmonar y la insuficiencia cardíaca. Estos receptores también son objetivos importantes en la investigación sobre enfermedades cardiovasculares y cáncer. En CymitQuimica, ofrecemos una selección de moduladores de receptores de endotelina de alta calidad para apoyar su investigación en biología cardiovascular, oncología y fisiología vascular.
Se han encontrado 83 productos de "Receptor de endotelina"
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IRL-3630
CAS:<p>IRL 3460 is an enantiomer.</p>Fórmula:C31H40N4O6SPureza:98%Forma y color:SolidPeso molecular:596.74Atrial Natriuretic Peptide (ANP) (1-28), rat
CAS:Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.Fórmula:C128H205N45O39S2Pureza:98%Forma y color:SolidPeso molecular:3062.41Methylsolfonyl 25(S)-Δ7-dafachronic acid
Methylsulfonyl 25(S)-Δ7-dafachronic acid (compound 3) is a selective ssDAF-12 agonist with an IC50 value of 0.41 μM. It exhibits low cytotoxicity in HepG2 cells, with an IC50 value greater than 200 μM. Methylsulfonyl 25(S)-Δ7-dafachronic acid is applicable in the study of parasitic diseases.Fórmula:C28H45NO4SPeso molecular:491.30693[Lys4] Sarafotoxin S6c
CAS:[Lys4] Sarafotoxin S6c: potent partial endothelin receptor agonist; causes pig coronary contraction, EC50=1.5 nM.Fórmula:C105H153N27O36S5Forma y color:SolidPeso molecular:2529.82Endothelin-2 (49-69), human TFA
Endothelin-2 (49-69), human (TFA) is a 21-amino acid vasoactive peptide that binds to ET-RA and ET-RB.Fórmula:C117H161N26F3O34S4Pureza:98%Forma y color:SolidPeso molecular:2660.94SB234551
CAS:SB234551 is a selective antagonist of endothelin ETA receptor.Fórmula:C34H34N2O9Forma y color:SolidPeso molecular:614.64IRL-1038
CAS:<p>ETB endothelin receptor antagonist</p>Fórmula:C68H92N14O15S2Pureza:98%Forma y color:SolidPeso molecular:1409.67Sarafotoxin S6b
CAS:non-selective endothelin receptor agonistFórmula:C110H163N27O34S5Pureza:98%Forma y color:SolidPeso molecular:2567.96Sarafotoxin S6c
CAS:<p>Highly selective ETB endothelin receptor agonist (Ki values are 0.29 and 28000 nM at ETB and ETA receptors respectively).</p>Fórmula:C103H147N27O37S5Pureza:98%Forma y color:SolidPeso molecular:2516PD 142893
CAS:PD 142893 is a functional endothelin-stimulated vasoconstriction antagonist.Fórmula:C50H65N7O10Pureza:98%Forma y color:SolidPeso molecular:924.09Atrial natriuretic factor (1-28) (rat) TFA
ANP (1-28), rat (TFA) inhibits Ang II-induced endothelin-1 secretion; main circulating ANP form in rats.Fórmula:C130H206N45F3O41S2Pureza:98%Forma y color:SolidPeso molecular:3176.43Endothelin-3 (Rat,Human) (TFA)
Endothelin-3 (Rat, Human) (TFA) is a 21-amino acid vasoactive peptide of endothelial origi, an agonist for the endothelin receptor type B (EDNRB).Fórmula:C123H169F3N26O35S4·xC2HF3O2Pureza:98%Forma y color:SolidPeso molecular:2757.07 (free base)Macitentan
CAS:Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).Fórmula:C19H20Br2N6O4SPureza:98% - >99.99%Forma y color:SolidPeso molecular:588.27Bosentan (hydrate)
CAS:Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.Fórmula:C27H29N5O6S·H2OPureza:99.31% - 99.86%Forma y color:White PowderPeso molecular:569.63Darusentan
CAS:Darusentan (Lu-135252) is a potent inhibitor of endothelin signaling and function in both large and small arteriesFórmula:C22H22N2O6Pureza:98.72%Forma y color:SolidPeso molecular:410.43BQ-123
CAS:BQ-123 is a selective endothelin A receptor (ETA) antagonist with IC50 of 7.3 nM. Phase 2.Fórmula:C31H42N6O7Pureza:99.22% - ≥95%Forma y color:SolidPeso molecular:610.7BQ-788 sodium salt
CAS:BQ-788 sodium salt is a potent and selective antagonist of ETB receptor(ETB receptors with an IC50 of 1.2 nM in human Girrardi heart cells).Fórmula:C34H51N5NaO7Forma y color:SolidPeso molecular:664.8ANP(1-28) Acetate (human, porcine)
CAS:<p>Carperitide acetate: 28-amino acid hormone from human heart, counters cardiac injury/stretch, reduces endothelin-1.</p>Fórmula:C129H207N45O41S3Pureza:98.24%Forma y color:SolidPeso molecular:3140.5Ambrisentan sodium
CAS:Ambrosentan (BSF 208075) sodium is a selective and oral effective antagonist of ET type A receptor ( ETAR ).Fórmula:C22H21N2NaO4Forma y color:SolidPeso molecular:400.41Sitaxsentan sodium
CAS:Sitaxsentan sodium (TBC11251 sodium salt) is a highly selective antagonist of endothelin A receptors.Fórmula:C18H14ClN2O6S2·NaPureza:98.39% - 99.01%Forma y color:SolidPeso molecular:476.89
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