Receptor de endotelina
Los receptores de endotelina son GPCR que median los efectos de las endotelinas, péptidos vasoconstrictores potentes que desempeñan un papel significativo en la regulación del tono vascular, el control de la presión arterial y la proliferación celular. Los antagonistas de los receptores de endotelina se utilizan en el tratamiento de afecciones como la hipertensión arterial pulmonar y la insuficiencia cardíaca. Estos receptores también son objetivos importantes en la investigación sobre enfermedades cardiovasculares y cáncer. En CymitQuimica, ofrecemos una selección de moduladores de receptores de endotelina de alta calidad para apoyar su investigación en biología cardiovascular, oncología y fisiología vascular.
Se han encontrado 87 productos para "Receptor de endotelina".
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Aprocitentan
CAS:Aprocitentan (ACT-132577) is ETA and ETB antagonist .Fórmula:C16H14Br2N6O4SPureza:97.35%Forma y color:White SolidPeso molecular:546.19Ref: TM-T7817
1mg55,00€5mg110,00€1mL*10mM (DMSO)135,00€10mg166,00€25mg295,00€50mg416,00€100mg622,00€200mg840,00€Macitentan
CAS:Macitentan (ACT-064992) is an endothelin receptor antagonist that is used in the therapy of pulmonary arterial hypertension (PAH).Fórmula:C19H20Br2N6O4SPureza:98% - >99.99%Forma y color:White SolidPeso molecular:588.27Atrasentan
CAS:Atrasentan (ABT-627) is an endothelin receptor antagonist that can inhibit the activity of ETA.Cost-effective and quality-assured.Fórmula:C29H38N2O6Pureza:97.65% - 99.08%Forma y color:SolidPeso molecular:510.62Ref: TM-TQ0259
1mg46,00€5mg90,00€1mL*10mM (DMSO)101,00€10mg130,00€25mg250,00€50mg356,00€100mg580,00€200mg798,00€Atrasentan sodium
CAS:Atrasentan (ABT-627) is an oral ETA receptor blocker with potential cancer-fighting properties, inhibiting angiogenesis and tumor growth.Fórmula:C29H37N2NaO6Forma y color:SolidPeso molecular:532.61RO 46-8443
CAS:RO 46-8443: First non-peptide ETB receptor antagonist, >2000-fold ETB selectivity in binding and function.Fórmula:C31H35N3O8SPureza:98.77% - 99.77%Forma y color:White SolidPeso molecular:609.69Sitaxsentan sodium
CAS:Sitaxsentan sodium (TBC11251 sodium salt) is a highly selective antagonist of endothelin A receptors.Fórmula:C18H14ClN2O6S2·NaPureza:99% - 99.19%Forma y color:Red SolidPeso molecular:476.89Bosentan (hydrate)
CAS:Bosentan hydrate (Ro 47-0203) is a competitive and dual antagonist of endothelin-1 at the endothelin-A (ET-A) and endothelin-B (ET-B) receptors.Fórmula:C27H29N5O6S·H2OPureza:99.31% - 99.86%Forma y color:SolidPeso molecular:569.63Ambrisentan sodium
CAS:Ambrosentan (BSF 208075) sodium is a selective and oral effective antagonist of ET type A receptor ( ETAR ).Fórmula:C22H21N2NaO4Forma y color:SolidPeso molecular:400.41Sparsentan
CAS:Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM,Fórmula:C32H40N4O5SPureza:97.94% - 99.88%Forma y color:White SolidPeso molecular:592.75Ref: TM-T5355
2mg37,00€5mg55,00€1mL*10mM (DMSO)73,00€10mg89,00€25mg161,00€50mg245,00€100mg360,00€200mg512,00€BMS 182874 hydrochloride
CAS:BMS 182874 hydrochloride is a nonpeptide endothelin (El) receptor antagonist.Fórmula:C17H20ClN3O3SPureza:97.01%Forma y color:Yellow SolidPeso molecular:381.88Ref: TM-T21790
1mg77,00€2mg92,00€5mg140,00€1mL*10mM (DMSO)146,00€10mg205,00€25mg343,00€50mg477,00€100mg665,00€200mg897,00€BQ-788 sodium salt
CAS:BQ-788 sodium salt is a potent selective endothelin receptor B antagonist inhibiting endothelin-1 binding at nanomolar levels.Fórmula:C34H51N5NaO7Pureza:98.11%Forma y color:SolidPeso molecular:664.80Endothelin-2 (49-69), human
CAS:Endothelin-2 (49-69), human (Human endothelin-2) is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.Fórmula:C115H160N26O32S4Pureza:98.26%Forma y color:White SolidPeso molecular:2546.92Nebentan potassium
CAS:Nebentan potassium (YM598) is an ETA receptor antagonist that inhibits pulmonary arterial hypertension and is used in the study of neurologic diseases.Fórmula:C24H20KN5O5SPureza:99.42%Forma y color:SolidPeso molecular:529.61Ref: TM-T36008
1mg52,00€2mg77,00€5mg111,00€1mL*10mM (DMSO)133,00€10mg177,00€25mg313,00€50mg502,00€100mg680,00€200mg888,00€Atrial natriuretic factor (1-28) (rat) TFA
Atrial natriuretic factor (1-28) (rat) TFA is the main circulating ANP form in rats, inhibiting Ang II-stimulated endothelin-1 secretion.Fórmula:C130H206N45F3O41S2Pureza:99.85%Forma y color:SolidPeso molecular:3176.43Zibotentan
CAS:Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.Fórmula:C19H16N6O4SPureza:97.00% - 97.02%Forma y color:White SolidPeso molecular:424.43Sulfatroxazole
CAS:Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of the ETA receptor with an IC50 of 0.26 μM.Fórmula:C11H13N3O3SForma y color:SolidPeso molecular:267.3WS 009A
CAS:WS 009A is an antagonist of the endothelin receptor.Fórmula:C24H25NO10SPureza:98%Forma y color:SolidPeso molecular:519.52PD-159020
CAS:PD-159020 is a non-selective antagonist of ETA/ETB(hETA and hETB with IC50s of 30 and 50 nM , respectively).Fórmula:C32H25NO8Pureza:98%Forma y color:SolidPeso molecular:551.54Aminaftone
CAS:Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.Fórmula:C18H15NO4Pureza:96.31% - 97.57%Forma y color:SolidPeso molecular:309.32Avosentan
CAS:Avosentan（Ro 67-0565; SPP-301） is a potent endothelin receptor (ETA) antagonist.Cost-effective and quality-assured.Fórmula:C23H21N5O5SPureza:98.31% - 99.90%Forma y color:SolidPeso molecular:479.51
